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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
1968 1
1969 4
1970 2
1971 3
1972 5
1973 7
1974 7
1975 5
1976 3
1977 4
1978 9
1979 6
1980 4
1981 2
1982 3
1983 6
1984 7
1985 4
1986 6
1987 4
1988 11
1989 8
1990 13
1991 17
1992 15
1993 18
1994 31
1995 37
1996 25
1997 60
1998 61
1999 65
2000 54
2001 66
2002 59
2003 78
2004 100
2005 104
2006 90
2007 105
2008 104
2009 116
2010 96
2011 112
2012 103
2013 113
2014 107
2015 94
2016 72
2017 71
2018 64
2019 70
2020 56
2021 38
2022 24
2023 26
2024 11

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2,122 results

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Quoted phrase not found in phrase index: "Abnormal forebrain morphology"
Page 1
Dystonia.
Balint B, Mencacci NE, Valente EM, Pisani A, Rothwell J, Jankovic J, Vidailhet M, Bhatia KP. Balint B, et al. Nat Rev Dis Primers. 2018 Sep 20;4(1):25. doi: 10.1038/s41572-018-0023-6. Nat Rev Dis Primers. 2018. PMID: 30237473 Review.
Dystonia is a neurological condition characterized by abnormal involuntary movements or postures owing to sustained or intermittent muscle contractions. ...The diagnosis of dystonia is largely based on clinical signs, and the diagnosis and aetiological definition of …
Dystonia is a neurological condition characterized by abnormal involuntary movements or postures owing to sustained or intermittent m …
Functional organization of the basal ganglia: therapeutic implications for Parkinson's disease.
Obeso JA, Rodríguez-Oroz MC, Benitez-Temino B, Blesa FJ, Guridi J, Marin C, Rodriguez M. Obeso JA, et al. Mov Disord. 2008;23 Suppl 3:S548-59. doi: 10.1002/mds.22062. Mov Disord. 2008. PMID: 18781672 Review.
Replacement therapy with standard levodopa creates a further imbalance, producing an abnormal pattern of neuronal discharge and synchronization of neuronal firing that sustain the "off" and "on with dyskinesia" states. ...
Replacement therapy with standard levodopa creates a further imbalance, producing an abnormal pattern of neuronal discharge and synch …
Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome.
Pinto B, Morelli G, Rastogi M, Savardi A, Fumagalli A, Petretto A, Bartolucci M, Varea E, Catelani T, Contestabile A, Perlini LE, Cancedda L. Pinto B, et al. Neuron. 2020 Dec 9;108(5):887-904.e12. doi: 10.1016/j.neuron.2020.09.010. Epub 2020 Oct 6. Neuron. 2020. PMID: 33027640 Free PMC article.
In the hippocampus of the Dp(16) mouse model of DS and DS individuals, we found activated microglia, as assessed by their morphology; activation markers; and, for DS mice, electrophysiological profile. ...
In the hippocampus of the Dp(16) mouse model of DS and DS individuals, we found activated microglia, as assessed by their morphology; …
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Kang Y, Zhou Y, Li Y, Han Y, Xu J, Niu W, Li Z, Liu S, Feng H, Huang W, Duan R, Xu T, Raj N, Zhang F, Dou J, Xu C, Wu H, Bassell GJ, Warren ST, Allen EG, Jin P, Wen Z. Kang Y, et al. Nat Neurosci. 2021 Oct;24(10):1377-1391. doi: 10.1038/s41593-021-00913-6. Epub 2021 Aug 19. Nat Neurosci. 2021. PMID: 34413513 Free PMC article.
Bulk and single-cell gene expression analyses of FXS forebrain organoids revealed that the loss of FMRP altered gene expression in a cell-type-specific manner. ...Collectively, our study revealed molecular, cellular and electrophysiological abnormalities associated …
Bulk and single-cell gene expression analyses of FXS forebrain organoids revealed that the loss of FMRP altered gene expression in a …
Neuronal oscillations in Parkinson's disease.
Witcher M, Moran R, Tatter SB, Laxton AW. Witcher M, et al. Front Biosci (Landmark Ed). 2014 Jun 1;19(8):1291-9. doi: 10.2741/4282. Front Biosci (Landmark Ed). 2014. PMID: 24896351 Free article. Review.
Unique oscillatory patterns are associated with specific motor abnormalities in PD. Therapies, such as dopaminergic medication and deep brain stimulation that disrupt these abnormal neuronal oscillatory patterns produce symptomatic improvement in PD patients. These …
Unique oscillatory patterns are associated with specific motor abnormalities in PD. Therapies, such as dopaminergic medication and de …
Antisense oligonucleotide therapeutic approach for Timothy syndrome.
Chen X, Birey F, Li MY, Revah O, Levy R, Thete MV, Reis N, Kaganovsky K, Onesto M, Sakai N, Hudacova Z, Hao J, Meng X, Nishino S, Huguenard J, Pașca SP. Chen X, et al. Nature. 2024 Apr;628(8009):818-825. doi: 10.1038/s41586-024-07310-6. Epub 2024 Apr 24. Nature. 2024. PMID: 38658687 Free PMC article.
We discovered that the ASO-mediated switch from exon 8A to 8 robustly rescued defects in patient-derived cortical organoids and migration in forebrain assembloids. Leveraging a transplantation platform previously developed(7), we found that a single intrathecal ASO adminis …
We discovered that the ASO-mediated switch from exon 8A to 8 robustly rescued defects in patient-derived cortical organoids and migration in …
Postoperative seizure and memory outcome of temporal lobe epilepsy with hippocampal sclerosis: A systematic review.
Li Y, Liu P, Lin Q, Zhou D, An D. Li Y, et al. Epilepsia. 2023 Nov;64(11):2845-2860. doi: 10.1111/epi.17757. Epub 2023 Sep 30. Epilepsia. 2023. PMID: 37611927 Review.
Seizure freedom and improved outcome (Engel 1 or ILAE class 1-2) 1 year after surgery were defined as the primary and secondary seizure outcome. A random-effects meta-analysis by DerSimonian and Laird method was performed to obtain pooled risk ratio (RRs) with 95% confiden …
Seizure freedom and improved outcome (Engel 1 or ILAE class 1-2) 1 year after surgery were defined as the primary and secondary seizure outc …
Diabetes insipidus following resection of pituitary tumors.
Schreckinger M, Szerlip N, Mittal S. Schreckinger M, et al. Clin Neurol Neurosurg. 2013 Feb;115(2):121-6. doi: 10.1016/j.clineuro.2012.08.009. Epub 2012 Aug 24. Clin Neurol Neurosurg. 2013. PMID: 22921808 Review.
The body's inability to concentrate urine leaves the patient dehydrated and leads to metabolic abnormalities that can be life threatening if not recognized and treated in a timely manner with an exogenous AVP analog. ...
The body's inability to concentrate urine leaves the patient dehydrated and leads to metabolic abnormalities that can be life threate …
Abnormalities of Cortical Morphology and Structural Covariance Network in Patients with Subacute Basal Ganglia Stroke.
Yan S, Zhang G, Zhou Y, Tian T, Qin Y, Wu D, Lu J, Zhang S, Liu WV, Zhu W. Yan S, et al. Acad Radiol. 2022 Mar;29 Suppl 3:S157-S165. doi: 10.1016/j.acra.2021.08.011. Epub 2021 Sep 21. Acad Radiol. 2022. PMID: 34556428
Changes of large-scale, cortical structural brain networks after basal ganglia stroke are less well reported. We, therefore, aim to explore the abnormalities of cortical morphology and structural network topology in patients with unilateral basal ganglia stroke duri …
Changes of large-scale, cortical structural brain networks after basal ganglia stroke are less well reported. We, therefore, aim to explore …
Adolescent menstrual irregularity.
Mansfield MJ, Emans SJ. Mansfield MJ, et al. J Reprod Med. 1984 Jun;29(6):399-410. J Reprod Med. 1984. PMID: 6379175 Review.
Causes of amenorrhea in adolescents are pregnancy, drugs and systemic diseases, hypothalamic and pituitary amenorrhea, "postpill" amenorrhea; hyperprolactinemia, androgen resistance, congenital anomalies of the genital tract, and androgen excess. Despite the large number o …
Causes of amenorrhea in adolescents are pregnancy, drugs and systemic diseases, hypothalamic and pituitary amenorrhea, "postpill" amenorrhea …
2,122 results