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Quoted phrase not found in phrase index: "Abnormal morphology of erythroid progenitor cell"
Page 1
Myelodysplastic syndromes with ring sideroblasts (MDS-RS) and MDS/myeloproliferative neoplasm with RS and thrombocytosis (MDS/MPN-RS-T) - "2021 update on diagnosis, risk-stratification, and management".
Patnaik MM, Tefferi A. Patnaik MM, et al. Am J Hematol. 2021 Mar 1;96(3):379-394. doi: 10.1002/ajh.26090. Epub 2021 Jan 28. Am J Hematol. 2021. PMID: 33428785 Free article. Review.
DISEASE OVERVIEW: Ring sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. ...TREATMENT: Anemia and iron overload are complications seen in both and are managed similar to lower risk MDS and MPN. Luspatercept, a firs …
DISEASE OVERVIEW: Ring sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. . …
Uncovering perturbations in human hematopoiesis associated with healthy aging and myeloid malignancies at single-cell resolution.
Ainciburu M, Ezponda T, Berastegui N, Alfonso-Pierola A, Vilas-Zornoza A, San Martin-Uriz P, Alignani D, Lamo-Espinosa J, San-Julian M, Jiménez-Solas T, Lopez F, Muntion S, Sanchez-Guijo F, Molero A, Montoro J, Serrano G, Diaz-Mazkiaran A, Lasaga M, Gomez-Cabrero D, Diez-Campelo M, Valcarcel D, Hernaez M, Romero JP, Prosper F. Ainciburu M, et al. Elife. 2023 Jan 11;12:e79363. doi: 10.7554/eLife.79363. Elife. 2023. PMID: 36629404 Free PMC article.
Early hematopoiesis is a continuous process in which hematopoietic stem and progenitor cells (HSPCs) gradually differentiate toward specific lineages. ...To address this, Ainciburu, Ezponda et al. used a technique called single-cell RNA sequencing to study th …
Early hematopoiesis is a continuous process in which hematopoietic stem and progenitor cells (HSPCs) gradually differentiate t …
Abnormal erythropoiesis and the pathophysiology of chronic anemia.
Koury MJ. Koury MJ. Blood Rev. 2014 Mar;28(2):49-66. doi: 10.1016/j.blre.2014.01.002. Epub 2014 Jan 23. Blood Rev. 2014. PMID: 24560123 Review.
When erythrocyte production rate of erythrocytes is less than the rate of loss, chronic anemia develops. Normal erythropoiesis and specific abnormalities of erythropoiesis that cause chronic anemia are considered during three periods of differentiation: a) multilineage and …
When erythrocyte production rate of erythrocytes is less than the rate of loss, chronic anemia develops. Normal erythropoiesis and specific …
How to approach chronic anemia.
Koury MJ, Rhodes M. Koury MJ, et al. Hematology Am Soc Hematol Educ Program. 2012;2012:183-90. doi: 10.1182/asheducation-2012.1.183. Hematology Am Soc Hematol Educ Program. 2012. PMID: 23233579 Review.
We present herein an approach to diagnosing the cause of chronic anemia based on a patient's history and complete blood cell count (CBC). Four patterns that are encountered frequently in CBCs associated with chronic anemias are considered: (1) anemia with abnormal p …
We present herein an approach to diagnosing the cause of chronic anemia based on a patient's history and complete blood cell count (C …
Anemia in alcoholics.
Savage D, Lindenbaum J. Savage D, et al. Medicine (Baltimore). 1986 Sep;65(5):322-38. doi: 10.1097/00005792-198609000-00005. Medicine (Baltimore). 1986. PMID: 3747828
Examination of the blood smear revealed siderocytes in one-third of patients with sideroblastic marrows and dimorphic erythrocyte morphology in the majority. Dimorphic blood smears, however, were neither sensitive nor specific for sideroblastic change. Serum iron concentra …
Examination of the blood smear revealed siderocytes in one-third of patients with sideroblastic marrows and dimorphic erythrocyte morphol …
Diagnosis and classification of erythrocytoses and thrombocytoses.
Pearson TC. Pearson TC. Baillieres Clin Haematol. 1998 Dec;11(4):695-720. doi: 10.1016/s0950-3536(98)80035-8. Baillieres Clin Haematol. 1998. PMID: 10640213 Review.
An erythrocytosis describes an increased peripheral blood packed cell volume (PCV) and is deemed to be absolute or apparent depending on whether or not the measured red cell mass (RCM) is above the reference range. ...This latter new group would be used for patients …
An erythrocytosis describes an increased peripheral blood packed cell volume (PCV) and is deemed to be absolute or apparent depending …
Ringed sideroblasts in β-thalassemia.
Cattivelli K, Campagna DR, Schmitz-Abe K, Heeney MM, Yaish HM, Caruso Brown AE, Kearney S, Walkovich K, Markianos K, Fleming MD, Neufeld EJ. Cattivelli K, et al. Pediatr Blood Cancer. 2017 May;64(5):10.1002/pbc.26324. doi: 10.1002/pbc.26324. Epub 2016 Nov 3. Pediatr Blood Cancer. 2017. PMID: 27808451 Free PMC article.
We describe a series of patients with beta-thalassemia whose diagnosis was delayed, required bone marrow examination in one affected member of each family, and revealed ringed sideroblasts, highlighting the association of this morphological finding with these disorders. Thus, in …
We describe a series of patients with beta-thalassemia whose diagnosis was delayed, required bone marrow examination in one affected member …
Congenital dyserythropoietic anemia type III.
Sandström H, Wahlin A. Sandström H, et al. Haematologica. 2000 Jul;85(7):753-7. Haematologica. 2000. PMID: 10897128 Review.
BACKGROUND AND OBJECTIVES: Congenital dyserythropoietic anemia type III (CDA-III) is a group of very rare disorders characterized by similar bone marrow morphology. ...STATE OF ART AND PERSPECTIVES: The clinical and laboratory manifestations of CDA-III indicate that …
BACKGROUND AND OBJECTIVES: Congenital dyserythropoietic anemia type III (CDA-III) is a group of very rare disorders characterized by …
Recent advances in the understanding of myelodysplastic syndromes with ring sideroblasts.
Malcovati L, Cazzola M. Malcovati L, et al. Br J Haematol. 2016 Sep;174(6):847-58. doi: 10.1111/bjh.14215. Epub 2016 Jul 8. Br J Haematol. 2016. PMID: 27391606 Free article. Review.
Experimental evidence has shown that mutant SF3B1 results in the abnormal splicing of several genes, primarily due to misrecognition of 3' splice sites. ...Patients with MDS carrying the SF3B1 mutation show a homogeneous disease phenotype characterized by isolated eryth …
Experimental evidence has shown that mutant SF3B1 results in the abnormal splicing of several genes, primarily due to misrecognition …
Membrane proteins in paroxysmal nocturnal haemoglobinuria.
Rotoli B, Bessler M, Alfinito F, del Vecchio L. Rotoli B, et al. Blood Rev. 1993 Jun;7(2):75-86. doi: 10.1016/s0268-960x(05)80017-7. Blood Rev. 1993. PMID: 8369662 Review.
A review of recent information on the abnormalities of the blood cell membrane in paroxysmal nocturnal haemoglobinuria (PNH) is presented, with a detailed analysis of biochemical and flow cytometry findings. ...Available data on in vitro culture of progenitor …
A review of recent information on the abnormalities of the blood cell membrane in paroxysmal nocturnal haemoglobinuria (PNH) i …
200 results