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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1971 1
1972 1
1974 1
1975 2
1976 2
1977 1
1978 8
1979 3
1980 1
1981 1
1982 2
1984 1
1985 2
1986 2
1987 2
1988 4
1989 5
1990 4
1992 4
1993 3
1994 6
1995 2
1996 9
1997 10
1998 11
1999 12
2000 8
2001 9
2002 11
2003 11
2004 10
2005 10
2006 17
2007 15
2008 20
2009 19
2010 18
2011 12
2012 18
2013 19
2014 13
2015 12
2016 8
2017 21
2018 14
2019 13
2020 15
2021 5
2022 5
2023 2
2024 2

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375 results

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Quoted phrase not found in phrase index: "Abnormal optic nerve morphology"
Page 1
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.
Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO. Kass MA, et al. Arch Ophthalmol. 2002 Jun;120(6):701-13; discussion 829-30. doi: 10.1001/archopht.120.6.701. Arch Ophthalmol. 2002. PMID: 12049574 Clinical Trial.
There is no consensus on the efficacy of medical treatment in delaying or preventing the onset of POAG in individuals with elevated IOP. Therefore, we designed a randomized clinical trial, the Ocular Hypertension Treatment Study. ...MAIN OUTCOME MEASURES: The …
There is no consensus on the efficacy of medical treatment in delaying or preventing the onset of POAG in individuals with elevated IOP. The …
Pituitary incidentaloma.
Orija IB, Weil RJ, Hamrahian AH. Orija IB, et al. Best Pract Res Clin Endocrinol Metab. 2012 Feb;26(1):47-68. doi: 10.1016/j.beem.2011.07.003. Best Pract Res Clin Endocrinol Metab. 2012. PMID: 22305452 Review.
Pituitary incidentalomas (PIs) are commonly encountered in clinical practice. While most are microincidentalomas (<1 cm) and not functional, in some cases their identification may lead to discovery of unrecognized abnormalities such as pituitary hormonal deficien …
Pituitary incidentalomas (PIs) are commonly encountered in clinical practice. While most are microincidentalomas (<1 cm) and not f …
Gene therapy for inherited retinal and optic nerve degenerations.
Moore NA, Morral N, Ciulla TA, Bracha P. Moore NA, et al. Expert Opin Biol Ther. 2018 Jan;18(1):37-49. doi: 10.1080/14712598.2018.1389886. Epub 2017 Oct 23. Expert Opin Biol Ther. 2018. PMID: 29057663 Free article. Review.
INTRODUCTION: The eye is a target for investigational gene therapy due to the monogenic nature of many inherited retinal and optic nerve degenerations (IRD), its accessibility, tight blood-ocular barrier, the ability to non-invasively monitor for functional and anat …
INTRODUCTION: The eye is a target for investigational gene therapy due to the monogenic nature of many inherited retinal and optic
Optic nerve ultrasonography in the evaluation of the relationship between arachnoid cyst and headache.
Sarigecili E, Bilen S, Gokay SS, Ucar HKOC, Dilek O. Sarigecili E, et al. Childs Nerv Syst. 2022 Aug;38(8):1573-1579. doi: 10.1007/s00381-022-05535-2. Epub 2022 Apr 23. Childs Nerv Syst. 2022. PMID: 35460353
Demographic data of the patients, the onset of headache time, clinical severity, electroencephalography (EEG) findings, optic nerve sheath diameter (ONSD) measurements by ultrasonography, and the volume of arachnoid cyst on brain MRI were determined and compa …
Demographic data of the patients, the onset of headache time, clinical severity, electroencephalography (EEG) findings, optic
Radiation-induced optic neuropathy.
Danesh-Meyer HV. Danesh-Meyer HV. J Clin Neurosci. 2008 Feb;15(2):95-100. doi: 10.1016/j.jocn.2007.09.004. J Clin Neurosci. 2008. PMID: 18068989 Review.
Several factors are associated with a higher risk for developing RION or for RION occurring with lower total doses of radiation. These include age, pre-existing compression of the optic nerve and chiasm by tumour, concurrent chemotherapy or previous external beam ra …
Several factors are associated with a higher risk for developing RION or for RION occurring with lower total doses of radiation. These inclu …
Neurophysiological markers.
Leocani L, Comi G. Leocani L, et al. Neurol Sci. 2008 Sep;29 Suppl 2:S218-21. doi: 10.1007/s10072-008-0942-1. Neurol Sci. 2008. PMID: 18690497 Review.
Their usefulness in the assessment of disease activity is limited by the fact that, although they can also reveal clinically silent lesions, EPs abnormalities are present only if their corresponding pathway is involved. With this respect, EPs have been extensively replaced …
Their usefulness in the assessment of disease activity is limited by the fact that, although they can also reveal clinically silent lesions, …
Longitudinal Changes in Vision and Retinal Morphology in Wolfram Syndrome.
O'Bryhim BE, Samara A, Chen L, Hershey T, Tychsen L, Hoekel J. O'Bryhim BE, et al. Am J Ophthalmol. 2022 Nov;243:10-18. doi: 10.1016/j.ajo.2022.07.003. Epub 2022 Jul 16. Am J Ophthalmol. 2022. PMID: 35850251
PURPOSE: To report long-term ophthalmic findings in Wolfram syndrome, including rates of visual decline, macular thinning, retinal nerve fiber layer (RNFL) thinning, and outer plexiform layer (OPL) lamination. ...METHODS: A total of 38 participants were studied, who underw …
PURPOSE: To report long-term ophthalmic findings in Wolfram syndrome, including rates of visual decline, macular thinning, retinal nerve
GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models.
Gorgogietas V, Rajaei B, Heeyoung C, Santacreu BJ, Marín-Cañas S, Salpea P, Sawatani T, Musuaya A, Arroyo MN, Moreno-Castro C, Benabdallah K, Demarez C, Toivonen S, Cosentino C, Pachera N, Lytrivi M, Cai Y, Carnel L, Brown C, Urano F, Marchetti P, Gilon P, Eizirik DL, Cnop M, Igoillo-Esteve M. Gorgogietas V, et al. Diabetologia. 2023 Jul;66(7):1306-1321. doi: 10.1007/s00125-023-05905-8. Epub 2023 Mar 30. Diabetologia. 2023. PMID: 36995380 Free PMC article.
AIMS/HYPOTHESIS: Wolfram syndrome is a rare autosomal recessive disorder caused by pathogenic variants in the WFS1 gene. It is characterised by insulin-dependent diabetes mellitus, optic nerve atrophy, diabetes insipidus, hearing loss and neurodegeneration. ...
AIMS/HYPOTHESIS: Wolfram syndrome is a rare autosomal recessive disorder caused by pathogenic variants in the WFS1 gene. It is characterised …
Neurofibromatosis Type 1: Review and Update on Emerging Therapies.
Karaconji T, Whist E, Jamieson RV, Flaherty MP, Grigg JRB. Karaconji T, et al. Asia Pac J Ophthalmol (Phila). 2019 Jan-Feb;8(1):62-72. doi: 10.22608/APO.2018182. Epub 2018 Nov 2. Asia Pac J Ophthalmol (Phila). 2019. PMID: 30387339 Free article. Review.
Early diagnosis and management led by a multidisciplinary team remains the standard of care, particularly in the management of optic pathway glioma. Emerging concepts in the genetic patterns of this condition have led to the introduction of new treatment modalities that ta …
Early diagnosis and management led by a multidisciplinary team remains the standard of care, particularly in the management of optic
Neuro-ophthalmic deficits after head trauma.
Jacobs SM, Van Stavern GP. Jacobs SM, et al. Curr Neurol Neurosci Rep. 2013 Nov;13(11):389. doi: 10.1007/s11910-013-0389-5. Curr Neurol Neurosci Rep. 2013. PMID: 24027004 Review.
When assessing afferent pathway injuries, a stepwise approach to evaluating visual acuity, pupils, color perception, and visual fields is critical. Traumatic optic neuropathy is of especial importance and its management must be tailored on a case-by-case basis. Efferent pa …
When assessing afferent pathway injuries, a stepwise approach to evaluating visual acuity, pupils, color perception, and visual fields is cr …
375 results