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1978 3
1985 1
1986 1
1992 2
1996 1
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2012 1
2017 1
2018 1
2024 0

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14 results

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Page 1
Familial essential thrombocythemia.
Eyster ME, Saletan SL, Rabellino EM, Karanas A, McDonald TP, Locke LA, Luderer JR. Eyster ME, et al. Am J Med. 1986 Mar;80(3):497-502. doi: 10.1016/0002-9343(86)90727-8. Am J Med. 1986. PMID: 3953624
Primary or essential thrombocythemia is rarely observed in childhood, and familial occurrence has been reported only once. ...The propositus had a persistent elevation of the platelet count, splenomegaly, a normal hemoglobin level, a normal white blood cell count, and a
Primary or essential thrombocythemia is rarely observed in childhood, and familial occurrence has been reported only once. ...The pro …
Essential thrombocythemia in children.
Dror Y, Zipursky A, Blanchette VS. Dror Y, et al. J Pediatr Hematol Oncol. 1999 Sep-Oct;21(5):356-63. doi: 10.1097/00043426-199909000-00005. J Pediatr Hematol Oncol. 1999. PMID: 10524447 Review.
PATIENTS AND METHODS: The authors analyzed 36 children, ages 6 weeks to 18 years, by combining descriptions of 2 patients observed at their institution with 34 patients reported in the English medical literature. ...Common abnormalities included large platelets, increased …
PATIENTS AND METHODS: The authors analyzed 36 children, ages 6 weeks to 18 years, by combining descriptions of 2 patients observed at …
An update on pediatric bleeding disorders: bleeding scores, benign joint hypermobility, and platelet function testing in the evaluation of the child with bleeding symptoms.
O'Brien SH. O'Brien SH. Am J Hematol. 2012 May;87 Suppl 1:S40-4. doi: 10.1002/ajh.23157. Epub 2012 Mar 28. Am J Hematol. 2012. PMID: 22460356 Free article. Review.
We will then discuss the relationship between benign hypermobility syndromes and hemostasis, and the importance of including a Beighton Score in the physical examination of any child presenting with unusual bruising or bleeding. While prolonged bleeding times and abnorm
We will then discuss the relationship between benign hypermobility syndromes and hemostasis, and the importance of including a Beighton S
Glanzmann thrombasthenia in children from Argentina.
Sassetti B, Lajmanovich A, Vázquez A, Vizcarguénaga MI, Berthier R, Aversa L, Bustelo P, Kordich L. Sassetti B, et al. J Pediatr Hematol Oncol. 1996 Feb;18(1):23-8. doi: 10.1097/00043426-199602000-00005. J Pediatr Hematol Oncol. 1996. PMID: 8556365
The diagnosis must be considered in patients presenting with mucocutaneous bleeding, purpura, a normal platelet count, abnormal platelet aggregation, and a prolonged bleeding time. In most of the patients, the presence of small amounts of either GPIIb or GPII …
The diagnosis must be considered in patients presenting with mucocutaneous bleeding, purpura, a normal platelet count, abnormal pl
Effect of psoralen and ultraviolet A on platelet functioning: an in vitro and in vivo study.
Procaccini EM, Pandolfi G, Monfrecola G, Rotoli B. Procaccini EM, et al. Photodermatol Photoimmunol Photomed. 1992 Feb;9(1):4-7. Photodermatol Photoimmunol Photomed. 1992. PMID: 1390123
At basal conditions and following exposure to UVA light alone, no changes in the normal platelet aggregation patterns were observed. Exposure to UVA light of PRP containing 8-MOP also demonstrated no abnormality in the platelet aggregation patterns at 8-MOP concentrations …
At basal conditions and following exposure to UVA light alone, no changes in the normal platelet aggregation patterns were observed. …
Hemostatic defects in Thai adolescents with menorrhagia.
Hutspardol S, Sirachainan N, Soisamrong A, Atchararit N, O-Prasertsawat P, Chuansumrit A. Hutspardol S, et al. J Med Assoc Thai. 2010 Apr;93(4):436-42. J Med Assoc Thai. 2010. PMID: 20462086
In addition, the authors also found an abnormal platelet aggregation with adrenaline stimulant in 15 (75%) among 20 healthy female controls who had no history of bleeding diathesis. No significant difference infrequency of abnormal platelet a
In addition, the authors also found an abnormal platelet aggregation with adrenaline stimulant in 15 (75%) among 20 hea …
Molecular phenotype and bleeding risks of an inherited platelet disorder in a family with a RUNX1 frameshift mutation.
Badin MS, Iyer JK, Chong M, Graf L, Rivard GE, Waye JS, Paterson AD, Pare G, Hayward CPM. Badin MS, et al. Haemophilia. 2017 May;23(3):e204-e213. doi: 10.1111/hae.13169. Epub 2017 Feb 8. Haemophilia. 2017. PMID: 28181366
RESULTS: Among 12 index cases who had their exomes sequenced, one individual from a family with eight study participants had a c.583dup in RUNX1 that segregated with the disease and was predicted to cause a frameshift and RUNX1 haploinsufficiency. Unlike unaffected family …
RESULTS: Among 12 index cases who had their exomes sequenced, one individual from a family with eight study participants had a c.583dup in R …
Platelet dysfunction induced by parenteral carbenicillin and ticarcillin. Studies of the dose-response relationship and mechanism of action in dogs.
Johnson GJ, Rao GH, White JG. Johnson GJ, et al. Am J Pathol. 1978 Apr;91(1):85-106. Am J Pathol. 1978. PMID: 645824 Free PMC article.
Dose- and time-dependent platelet dysfunction was uniformly observed during the administration of CARB or TIC, 250 to 1000 mg/kg/24 hr. ...CARB and TIC infusions resulted in inhibition of 14C-serotonin release and slightly decreased platelet ADP, while serotonin, ATP, and …
Dose- and time-dependent platelet dysfunction was uniformly observed during the administration of CARB or TIC, 250 to 1000 mg/kg/24 h …
Abnormal platelet aggregation associated with fluoxetine therapy.
Alderman CP, Moritz CK, Ben-Tovim DI. Alderman CP, et al. Ann Pharmacother. 1992 Dec;26(12):1517-9. doi: 10.1177/106002809202601205. Ann Pharmacother. 1992. PMID: 1482806
CASE SUMMARY: A 49-year-old man developed a release-type defect in platelet aggregation during treatment with fluoxetine. Abnormal platelet aggregation was observed during platelet viability testing, in which adenosine diphosphate, epinephrine, ristoce …
CASE SUMMARY: A 49-year-old man developed a release-type defect in platelet aggregation during treatment with fluoxetine. Abnormal
Histone-Complexed DNA Fragments Levels are Associated with Coagulopathy, Endothelial Cell Damage, and Increased Mortality after Severe Pediatric Trauma.
Russell RT, Christiaans SC, Nice TR, Banks M, Mortellaro VE, Morgan C, Duhachek-Stapelman A, Lisco SJ, Kerby JD, Wagener BM, Chen MK, Pittet JF. Russell RT, et al. Shock. 2018 Jan;49(1):44-52. doi: 10.1097/SHK.0000000000000902. Shock. 2018. PMID: 28509684
We hypothesized that pediatric trauma patients with increased levels of histone-complexed DNA fragments (hcDNA) would have evidence of coagulopathy and endothelial damage that would be associated with poor outcomes. METHODS: We conducted a prospective observational study o …
We hypothesized that pediatric trauma patients with increased levels of histone-complexed DNA fragments (hcDNA) would have evidence of coagu …
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