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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1970 1
1972 2
1973 3
1975 7
1976 7
1977 7
1978 3
1979 1
1980 4
1981 8
1982 2
1983 15
1984 7
1985 9
1986 10
1987 12
1988 6
1989 10
1990 9
1991 3
1992 6
1993 15
1994 8
1995 19
1996 16
1997 16
1998 17
1999 19
2000 8
2001 12
2002 9
2003 13
2004 7
2005 6
2006 5
2007 7
2008 11
2009 13
2010 14
2011 24
2012 22
2013 23
2014 22
2015 19
2016 17
2017 10
2018 14
2019 26
2020 26
2021 16
2022 17
2023 7
2024 7

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547 results

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Quoted phrase not found in phrase index: "Abnormal spleen physiology"
Page 1
Primary myelofibrosis: 2023 update on diagnosis, risk-stratification, and management.
Tefferi A. Tefferi A. Am J Hematol. 2023 May;98(5):801-821. doi: 10.1002/ajh.26857. Epub 2023 Feb 6. Am J Hematol. 2023. PMID: 36680511 Free article. Review.
Type 1/like CALR mutation is associated with superior survival. KARYOTYPE: Very high-risk abnormalities include -7, inv (3), i(17q), +21, +19, 12p- and 11q-. Favorable risk abnormalities include normal karyotype or isolated +9, 13q-, 20q-, 1q abnormalities an …
Type 1/like CALR mutation is associated with superior survival. KARYOTYPE: Very high-risk abnormalities include -7, inv (3), i(17q), …
The spleen-strengthening and liver-draining herbal formula treatment of non-alcoholic fatty liver disease by regulation of intestinal flora in clinical trial.
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M. Hui D, et al. Front Endocrinol (Lausanne). 2023 Jan 19;13:1107071. doi: 10.3389/fendo.2022.1107071. eCollection 2022. Front Endocrinol (Lausanne). 2023. PMID: 36743913 Free PMC article. Clinical Trial.
OBJECTIVE: As a metabolic disease, one important feature of non-alcoholic fatty liver disease (NAFLD) is the disturbance of the intestinal flora. Spleen-strengthening and liver-draining formula (SLF) is a formula formed according to the theory of "One Qi Circulation" (Qing …
OBJECTIVE: As a metabolic disease, one important feature of non-alcoholic fatty liver disease (NAFLD) is the disturbance of the intestinal f …
AMP-activated protein kinase α1 phosphorylates PHD2 to maintain systemic iron homeostasis.
Wang C, Zhang W, Xu W, Liu Z, Huang K. Wang C, et al. Clin Transl Med. 2022 May;12(5):e854. doi: 10.1002/ctm2.854. Clin Transl Med. 2022. PMID: 35538889 Free PMC article.
RESULTS: We found that mice with global deficiency of AMPKalpha1, but not AMPKalpha2, exhibited hypoferraemia as well as iron sequestration in the spleen and liver. Hepatocyte-specific, but not myeloid-specific, ablation of AMPKalpha1 also reduced serum iron levels in asso …
RESULTS: We found that mice with global deficiency of AMPKalpha1, but not AMPKalpha2, exhibited hypoferraemia as well as iron sequestration …
AA-amyloidosis in cats (Felis catus) housed in shelters.
Ferri F, Ferro S, Porporato F, Callegari C, Guglielmetti C, Mazza M, Ferrero M, Crinò C, Gallo E, Drigo M, Coppola LM, Gerardi G, Schulte TP, Ricagno S, Vogel M, Storni F, Bachmann MF, Vogt AC, Caminito S, Mazzini G, Lavatelli F, Palladini G, Merlini G, Zini E. Ferri F, et al. PLoS One. 2023 Mar 29;18(3):e0281822. doi: 10.1371/journal.pone.0281822. eCollection 2023. PLoS One. 2023. PMID: 36989207 Free PMC article.
Aims of the study were to determine AA-amyloidosis prevalence in dead shelter cats. Liver, kidney, spleen and bile were collected at death in cats from 3 shelters. AA-amyloidosis was scored. ...The duration of stay in the shelters was positively associated with a histologi …
Aims of the study were to determine AA-amyloidosis prevalence in dead shelter cats. Liver, kidney, spleen and bile were collected at …
Birth defect co-occurrence patterns in the Texas Birth Defects Registry.
Benjamin RH, Scheuerle AE, Scott DA, Navarro Sanchez ML, Langlois PH, Canfield MA, Northrup H, Schaaf CP, Ray JW, McLean SD, Chen H, Swartz MD, Lupo PJ, Agopian AJ. Benjamin RH, et al. Pediatr Res. 2022 Apr;91(5):1278-1285. doi: 10.1038/s41390-021-01629-w. Epub 2021 Jun 30. Pediatr Res. 2022. PMID: 34193968 Free PMC article.
This work complements prior work that has suggested etiologic connections between select defects (e.g., diaphragmatic hernia and heart and spleen anomalies; heart and spine defects). IMPACT: In this large-scale, population-based study of birth defect co-occurrence patterns …
This work complements prior work that has suggested etiologic connections between select defects (e.g., diaphragmatic hernia and heart and …
Platelet phenotype and function in the absence of splenic sequestration (Review).
Luu S, Woolley IJ, Andrews RK. Luu S, et al. Platelets. 2021 Jan 2;32(1):47-52. doi: 10.1080/09537104.2020.1732322. Epub 2020 Feb 27. Platelets. 2021. PMID: 32106750 Review.
The spleen, in addition to its role in immunity, plays key roles in erythrocyte maintenance and platelet sequestration. ...Following splenectomy, a thrombocytosis is commonly seen secondary to the loss of the ability to sequester platelets. Abnormal platelet quality …
The spleen, in addition to its role in immunity, plays key roles in erythrocyte maintenance and platelet sequestration. ...Following …
Clinical relevance of endpoints in clinical trials for acid sphingomyelinase deficiency enzyme replacement therapy.
Jones SA, McGovern M, Lidove O, Giugliani R, Mistry PK, Dionisi-Vici C, Munoz-Rojas MV, Nalysnyk L, Schecter AD, Wasserstein M. Jones SA, et al. Mol Genet Metab. 2020 Sep-Oct;131(1-2):116-123. doi: 10.1016/j.ymgme.2020.06.008. Epub 2020 Jun 24. Mol Genet Metab. 2020. PMID: 32616389 Free article. Review.
The degree of splenomegaly correlates with short stature, atherogenic lipid profile, and degree of abnormality of hematologic parameters, and thus may be considered a surrogate marker for bleeding risk, abnormal lipid profiles and possibly, liver fibrosis. ...CONCLU …
The degree of splenomegaly correlates with short stature, atherogenic lipid profile, and degree of abnormality of hematologic paramet …
Novel targets to cure primary myelofibrosis from studies on Gata1low mice.
Zingariello M, Martelli F, Verachi P, Bardelli C, Gobbo F, Mazzarini M, Migliaccio AR. Zingariello M, et al. IUBMB Life. 2020 Jan;72(1):131-141. doi: 10.1002/iub.2198. Epub 2019 Nov 21. IUBMB Life. 2020. PMID: 31749302 Free PMC article. Review.
These observations cross-validated Gata1(low) mice as a bona fide animal model for PMF and prompted the use of this model to identify abnormalities that might be targeted to cure the disease. We will summarize here data generated in Gata1(low) mice indicating that t …
These observations cross-validated Gata1(low) mice as a bona fide animal model for PMF and prompted the use of this model to identify …
Clinical and Molecular Diagnosis of Osteocraniostenosis in Fetuses and Newborns: Prenatal Ultrasound, Clinical, Radiological and Pathological Features.
Rosato S, Unger S, Campos-Xavier B, Caraffi SG, Beltrami L, Pollazzon M, Ivanovski I, Castori M, Bonasoni MP, Comitini G, Nikkels PGJ, Lindstrom K, Umandap C, Superti-Furga A, Garavelli L. Rosato S, et al. Genes (Basel). 2022 Jan 28;13(2):261. doi: 10.3390/genes13020261. Genes (Basel). 2022. PMID: 35205306 Free PMC article. Review.
We review the main diagnostic signs of OCS both before and after birth based on our observations and on the literature. We then review the current knowledge on the mutational spectrum of FAM111A associated with either OCS or KCS, including three novel variants, both from o …
We review the main diagnostic signs of OCS both before and after birth based on our observations and on the literature. We then revie …
Mastocytosis and fibrosis: role of cytokines.
Li CY, Baek JY. Li CY, et al. Int Arch Allergy Immunol. 2002 Feb;127(2):123-6. doi: 10.1159/000048182. Int Arch Allergy Immunol. 2002. PMID: 11919421 Review.
Mastocytosis is a rare stem cell disorder characterized by abnormal growth and accumulation of mast cells in one or more organ systems. Clinical heterogeneity is a hallmark of mastocytosis. Recent observations of activating mutations in c-kit may help to understand …
Mastocytosis is a rare stem cell disorder characterized by abnormal growth and accumulation of mast cells in one or more organ system …
547 results