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124 results

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Quoted phrase not found in phrase index: "Abnormal synovial membrane morphology"
Page 1
TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models.
Wu J, Feng Z, Chen L, Li Y, Bian H, Geng J, Zheng ZH, Fu X, Pei Z, Qin Y, Yang L, Zhao Y, Wang K, Chen R, He Q, Nan G, Jiang X, Chen ZN, Zhu P. Wu J, et al. Nat Commun. 2022 Feb 3;13(1):676. doi: 10.1038/s41467-021-27948-4. Nat Commun. 2022. PMID: 35115492 Free PMC article.
Ferroptosis is a nonapoptotic cell death process that requires cellular iron and the accumulation of lipid peroxides. In progressive rheumatoid arthritis (RA), synovial fibroblasts proliferate abnormally in the presence of reactive oxygen species (ROS) and elevated …
Ferroptosis is a nonapoptotic cell death process that requires cellular iron and the accumulation of lipid peroxides. In progressive rheumat …
Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis.
Wu X, Liu Y, Jin S, Wang M, Jiao Y, Yang B, Lu X, Ji X, Fei Y, Yang H, Zhao L, Chen H, Zhang Y, Li H, Lipsky PE, Tsokos GC, Bai F, Zhang X. Wu X, et al. Nat Commun. 2021 Aug 17;12(1):4977. doi: 10.1038/s41467-021-25246-7. Nat Commun. 2021. PMID: 34404786 Free PMC article.
Here we profile CD45(+) hematopoietic cells from peripheral blood or synovial tissues from both ACPA+ and ACPA- RA patients by single-cell RNA sequencing and identify subsets of immune cells that contribute to the pathogenesis of RA subtypes. We find several synovial …
Here we profile CD45(+) hematopoietic cells from peripheral blood or synovial tissues from both ACPA+ and ACPA- RA patients by single …
The cardiometabolic conditions of psoriatic disease.
Toussirot E, Gallais-Sérézal I, Aubin F. Toussirot E, et al. Front Immunol. 2022 Sep 8;13:970371. doi: 10.3389/fimmu.2022.970371. eCollection 2022. Front Immunol. 2022. PMID: 36159785 Free PMC article. Review.
Psoriasis (PsO) and psoriatic arthritis (PsA), together known as psoriatic disease (PsD), are immune-mediated diseases with a chronic and relapsing course that affect the skin, the joints or both. The pathophysiology of PsO is complex and involves abnormal expression of ke …
Psoriasis (PsO) and psoriatic arthritis (PsA), together known as psoriatic disease (PsD), are immune-mediated diseases with a chronic and re …
Rheumatoid arthritis: sequences.
Scutellari PN, Orzincolo C. Scutellari PN, et al. Eur J Radiol. 1998 May;27 Suppl 1:S31-8. doi: 10.1016/s0720-048x(98)00040-0. Eur J Radiol. 1998. PMID: 9652499
The earliest abnormalities consist in synovial proliferation, soft tissue swelling, and osteoporosis. ...Magnetic resonance applications include the assessment of disease activity: in particular, this technique may be the only tool differentiating synovial fl …
The earliest abnormalities consist in synovial proliferation, soft tissue swelling, and osteoporosis. ...Magnetic resonance ap …
Sonographic synovial vascularity of synovitis in rheumatoid arthritis.
Fukae J, Tanimura K, Atsumi T, Koike T. Fukae J, et al. Rheumatology (Oxford). 2014 Apr;53(4):586-91. doi: 10.1093/rheumatology/ket311. Epub 2013 Sep 18. Rheumatology (Oxford). 2014. PMID: 24049097 Review.
RA is a condition of multiple synovitis. Abnormal synovial vascularity (SV) is evident with the onset of joint inflammation. ...
RA is a condition of multiple synovitis. Abnormal synovial vascularity (SV) is evident with the onset of joint inflammation. . …
Etiology of osteoarthritis: genetics and synovial joint development.
Sandell LJ. Sandell LJ. Nat Rev Rheumatol. 2012 Jan 10;8(2):77-89. doi: 10.1038/nrrheum.2011.199. Nat Rev Rheumatol. 2012. PMID: 22231237 Review.
Data derived from genetic analyses and genome-wide screening of individuals with this disease have revealed a surprising trend: genes associated with OA tend to be related to the process of synovial joint development. Mutations in these genes might directly cause OA. ...Ea …
Data derived from genetic analyses and genome-wide screening of individuals with this disease have revealed a surprising trend: genes associ …
Inflammation in osteoarthritis: is it time to dampen the alarm(in) in this debilitating disease?
van den Bosch MHJ. van den Bosch MHJ. Clin Exp Immunol. 2019 Feb;195(2):153-166. doi: 10.1111/cei.13237. Epub 2018 Nov 28. Clin Exp Immunol. 2019. PMID: 30421798 Free PMC article. Review.
For a long time, OA was considered a non-inflammatory disease that was the result of 'wear-and-tear' and abnormal mechanics, and therefore many considered the term 'osteoarthritis' a misnomer. ...
For a long time, OA was considered a non-inflammatory disease that was the result of 'wear-and-tear' and abnormal mechanics, and ther …
Cynanchum komarovii extract for the treatment of rheumatoid arthritis by acting on synovial cells in vitro and in vivo.
Hao F, Tao L, Liu J, Ma Y, Zhang J, Wang W, Yan W, Wang B, Wang X, Chen X, Ma Y, Fan H, Zhao X, Wang Z, Bai C. Hao F, et al. J Ethnopharmacol. 2023 Dec 5;317:116825. doi: 10.1016/j.jep.2023.116825. Epub 2023 Jun 20. J Ethnopharmacol. 2023. PMID: 37348792
When administered at doses up to 1000 mg/kg, CK extract significantly improved synovial lesions, increased bone density, and decreased abnormally elevated immune organ index in CIA rats. CONCLUSIONS: CK has significant anti-RA activity, and its anti-RA mechanism of …
When administered at doses up to 1000 mg/kg, CK extract significantly improved synovial lesions, increased bone density, and decrease …
Etiopathogenesis of osteoarthritis.
Brandt KD, Dieppe P, Radin EL. Brandt KD, et al. Rheum Dis Clin North Am. 2008 Aug;34(3):531-59. doi: 10.1016/j.rdc.2008.05.011. Rheum Dis Clin North Am. 2008. PMID: 18687271 Review.
In this article, the authors posit that, because osteoarthritis (OA) involves all of the tissues of the synovial joint, the emphasis on the loss of cartilage, in particular, is misguided. ...Because the body's innate mechanisms for repairing the damaged tissues cannot be e …
In this article, the authors posit that, because osteoarthritis (OA) involves all of the tissues of the synovial joint, the emphasis …
Implants for cranioplasty.
Gladstone HB, McDermott MW, Cooke DD. Gladstone HB, et al. Otolaryngol Clin North Am. 1995 Apr;28(2):381-400. Otolaryngol Clin North Am. 1995. PMID: 7596618 Review.
Yet foreign materials can cause excessive inflammation, producing a synovial membrane at the interface between the host bone and cranioplasty construct, increasing the risk of infection. ...
Yet foreign materials can cause excessive inflammation, producing a synovial membrane at the interface between the host bone a …
124 results