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1977 1
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384 results

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Quoted phrase not found in phrase index: "Abnormality of redox activity"
Page 1
U-shaped association of uric acid to overall-cause mortality and its impact on clinical management of hyperuricemia.
Crawley WT, Jungels CG, Stenmark KR, Fini MA. Crawley WT, et al. Redox Biol. 2022 May;51:102271. doi: 10.1016/j.redox.2022.102271. Epub 2022 Feb 17. Redox Biol. 2022. PMID: 35228125 Free PMC article. Review.
More recently, research has also shifted to the impact of hypouricemia, with multiple studies showing the potentially damaging effects that can be caused by abnormally low levels of SUA. Along with these observations, recent inconclusive data from human studies evaluating …
More recently, research has also shifted to the impact of hypouricemia, with multiple studies showing the potentially damaging effects that …
Melatonin protects against environmental stress-induced fetal growth restriction via suppressing ROS-mediated GCN2/ATF4/BNIP3-dependent mitophagy in placental trophoblasts.
Zhu HL, Shi XT, Xu XF, Zhou GX, Xiong YW, Yi SJ, Liu WB, Dai LM, Cao XL, Xu DX, Wang H. Zhu HL, et al. Redox Biol. 2021 Apr;40:101854. doi: 10.1016/j.redox.2021.101854. Epub 2021 Jan 6. Redox Biol. 2021. PMID: 33454563 Free PMC article.
Simultaneously, Cd triggered BNIP3-dependent mitophagy in placental trophoblasts, as determined by the degradation of mitochondrial proteins, including HSP60 and COX IV, and the accumulation of puncta representing co-localization of TOM20 with LC3B or BNIP3 with LC3B. Based on ou …
Simultaneously, Cd triggered BNIP3-dependent mitophagy in placental trophoblasts, as determined by the degradation of mitochondrial proteins …
Vitamin neurotoxicity.
Snodgrass SR. Snodgrass SR. Mol Neurobiol. 1992 Spring;6(1):41-73. doi: 10.1007/BF02935566. Mol Neurobiol. 1992. PMID: 1463588 Review.
Because vitamin A and analogs enter the CNS better than most vitamins, and because retinoids have many effects on enzyme activity and gene expression, Vitamin A neurotoxicity is more likely than that of most, perhaps all other vitamins. ...
Because vitamin A and analogs enter the CNS better than most vitamins, and because retinoids have many effects on enzyme activity and …
Redox Implications of Extreme Task Performance: The Case in Driver Athletes.
Reid MB. Reid MB. Cells. 2022 Mar 5;11(5):899. doi: 10.3390/cells11050899. Cells. 2022. PMID: 35269521 Free PMC article. Review.
Redox homeostasis and redox-mediated signaling mechanisms are fundamental elements of human biology. ...This article analyzes the impact of redox mechanisms on extreme task performance. Such activities (a) require complex motor skills, (b) are p
Redox homeostasis and redox-mediated signaling mechanisms are fundamental elements of human biology. ...This article analyzes
Novel Insights Regarding Nitric Oxide and Cardiovascular Diseases.
Infante T, Costa D, Napoli C. Infante T, et al. Angiology. 2021 May;72(5):411-425. doi: 10.1177/0003319720979243. Epub 2021 Jan 22. Angiology. 2021. PMID: 33478246 Review.
Nitric oxide (NO) is a powerful mediator with biological activities such as vasodilation and prevention of vascular smooth muscle cell proliferation as well as functional regulation of cardiac cells. Thus, impaired production or reduced bioavailability of NO predisposes to …
Nitric oxide (NO) is a powerful mediator with biological activities such as vasodilation and prevention of vascular smooth muscle cel …
Glyoxalase 1 Modulation in Obesity and Diabetes.
Rabbani N, Thornalley PJ. Rabbani N, et al. Antioxid Redox Signal. 2019 Jan 20;30(3):354-374. doi: 10.1089/ars.2017.7424. Epub 2018 Jan 2. Antioxid Redox Signal. 2019. PMID: 29160087 Review.
New approaches are required, particularly those addressing mechanism-based risk factors for health decline and disease progression. Recent Advances: Dicarbonyl stress is the abnormal accumulation of reactive dicarbonyl metabolites such as methylglyoxal (MG) leading to cell …
New approaches are required, particularly those addressing mechanism-based risk factors for health decline and disease progression. Recent A …
Outlook of Ferroptosis-Targeted Lipid Peroxidation in Cardiovascular Disease.
Wu ZF, Liu XY, Deng NH, Ren Z, Jiang ZS. Wu ZF, et al. Curr Med Chem. 2023;30(31):3550-3561. doi: 10.2174/0929867330666221111162905. Curr Med Chem. 2023. PMID: 36372915 Review.
Alternatively, Fe(2+) and Fe(3+) are required for the activity of LOXs and ferroptosis, and Fe(2+) can significantly accelerate lipid peroxidation in ferroptosis. Abnormal lipid metabolism is a certain risk factor for cardiovascular disease. ...
Alternatively, Fe(2+) and Fe(3+) are required for the activity of LOXs and ferroptosis, and Fe(2+) can significantly accelerate lipid …
Functional role of peroxiredoxin 6 in the eye.
Wahlig S, Lovatt M, Mehta JS. Wahlig S, et al. Free Radic Biol Med. 2018 Oct;126:210-220. doi: 10.1016/j.freeradbiomed.2018.08.017. Epub 2018 Aug 16. Free Radic Biol Med. 2018. PMID: 30120980 Review.
In addition to its peroxidase function, Prdx6 also demonstrates phospholipase A(2) and lysophosphatidylcholine acyl transferase (LPCAT) activities. These enzymatic activities play an important role in regenerating oxidized membrane phospholipids and maintaining an a …
In addition to its peroxidase function, Prdx6 also demonstrates phospholipase A(2) and lysophosphatidylcholine acyl transferase (LPCAT) a
Spectrophotometric Assays for Sensing Tyrosinase Activity and Their Applications.
Fan YF, Zhu SX, Hou FB, Zhao DF, Pan QS, Xiang YW, Qian XK, Ge GB, Wang P. Fan YF, et al. Biosensors (Basel). 2021 Aug 23;11(8):290. doi: 10.3390/bios11080290. Biosensors (Basel). 2021. PMID: 34436092 Free PMC article. Review.
Previous pharmacological investigations have revealed that an abnormal level of TYR is tightly associated with various dermatoses, including albinism, age spots, and malignant melanoma. TYR inhibitors can partially block the formation of pigment, which are always used for …
Previous pharmacological investigations have revealed that an abnormal level of TYR is tightly associated with various dermatoses, in …
The impact of glutathione metabolism in autism spectrum disorder.
Bjørklund G, Doşa MD, Maes M, Dadar M, Frye RE, Peana M, Chirumbolo S. Bjørklund G, et al. Pharmacol Res. 2021 Apr;166:105437. doi: 10.1016/j.phrs.2021.105437. Epub 2021 Jan 22. Pharmacol Res. 2021. PMID: 33493659 Review.
GSH plays a key role in the detoxification of xenobiotics and maintenance of balance in intracellular redox pathways. Recent data showed that imbalances in the GSH redox system are an important factor in the pathophysiology of ASD. ...GSSG can react with protein sul …
GSH plays a key role in the detoxification of xenobiotics and maintenance of balance in intracellular redox pathways. Recent data sho …
384 results