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Quoted phrase not found in phrase index: "Abnormality of von Willebrand factor"
Page 1
The role of VWF/FVIII in thrombosis and cancer progression in multiple myeloma and other hematological malignancies.
Comerford C, Glavey S, Quinn J, O'Sullivan JM. Comerford C, et al. J Thromb Haemost. 2022 Aug;20(8):1766-1777. doi: 10.1111/jth.15773. Epub 2022 Jun 23. J Thromb Haemost. 2022. PMID: 35644028 Free PMC article. Review.
The pathophysiology of thrombosis in MM is multifactorial and patients with MM appear to display a hypercoagulable phenotype with potential contributory factors including raised von Willebrand factor (VWF) levels, activated protein C resistance, impaired fibr …
The pathophysiology of thrombosis in MM is multifactorial and patients with MM appear to display a hypercoagulable phenotype with potential …
Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) in Japan 2023.
Matsumoto M, Miyakawa Y, Kokame K, Ueda Y, Wada H, Higasa S, Yagi H, Ogawa Y, Sakai K, Miyata T, Morishita E, Fujimura Y; For TTP group of Blood Coagulation Abnormalities Research Study Team, Research on Rare and Intractable diseases, Health and Labour Sciences Research Grants from the Ministry of Health, Labour and Welfare of Japan. Matsumoto M, et al. Int J Hematol. 2023 Nov;118(5):529-546. doi: 10.1007/s12185-023-03657-0. Epub 2023 Sep 10. Int J Hematol. 2023. PMID: 37689812 Free PMC article.
TTP is classified as immune-mediated TTP (iTTP) if the patient is positive for anti-ADAMTS13 autoantibodies, and as congenital TTP (cTTP) if ADAMTS13 gene abnormalities are detected. Fresh frozen plasma (FFP) transfusion is performed in patients with cTTP to supplem …
TTP is classified as immune-mediated TTP (iTTP) if the patient is positive for anti-ADAMTS13 autoantibodies, and as congenital TTP (c …
Consensus on the standardization of terminology in thrombotic thrombocytopenic purpura and related thrombotic microangiopathies.
Scully M, Cataland S, Coppo P, de la Rubia J, Friedman KD, Kremer Hovinga J, Lämmle B, Matsumoto M, Pavenski K, Sadler E, Sarode R, Wu H; International Working Group for Thrombotic Thrombocytopenic Purpura. Scully M, et al. J Thromb Haemost. 2017 Feb;15(2):312-322. doi: 10.1111/jth.13571. Epub 2017 Jan 30. J Thromb Haemost. 2017. PMID: 27868334 Free article.
The most common cause is disseminated intravascular coagulation, which may be differentiated by abnormal coagulation. Clinically, a number of conditions present with microangiopathic hemolytic anemia and thrombocytopenia, including cancer, infection, transplantation, drug …
The most common cause is disseminated intravascular coagulation, which may be differentiated by abnormal coagulation. Clinically, a n …
COVID-19 versus HIT hypercoagulability.
Warkentin TE, Kaatz S. Warkentin TE, et al. Thromb Res. 2020 Dec;196:38-51. doi: 10.1016/j.thromres.2020.08.017. Epub 2020 Aug 10. Thromb Res. 2020. PMID: 32841919 Free PMC article. Review.
., cerebral venous sinus thrombosis, mesenteric artery and vein thrombosis. Several hematology abnormalities have been observed in COVID-19 patients, including lymphopenia, neutrophilia, thrombocytopenia (usually mild), thrombocytosis, elevated prothrombin time and partial …
., cerebral venous sinus thrombosis, mesenteric artery and vein thrombosis. Several hematology abnormalities have been observed in CO …
Neurosurgical aspects of Noonan syndrome.
Saragosti E, Fattal-Valevski A, Levin D, Hausman-Kedem M, Constantini S, Mecica N, Zarour S, Roth J. Saragosti E, et al. Childs Nerv Syst. 2023 Apr;39(4):849-856. doi: 10.1007/s00381-023-05888-2. Epub 2023 Feb 27. Childs Nerv Syst. 2023. PMID: 36847963 Review.
PURPOSE: Noonan syndrome (NS) is a rare neurodevelopmental syndrome characterized by dysmorphic features, congenital heart defects, neurodevelopmental delay, and bleeding diathesis. ...Comorbidities included pulmonary stenosis in two patients and hypertrophic cardiomyopath …
PURPOSE: Noonan syndrome (NS) is a rare neurodevelopmental syndrome characterized by dysmorphic features, congenital heart defects, n …
How I treat von Willebrand disease.
Castaman G. Castaman G. Thromb Res. 2020 Dec;196:618-625. doi: 10.1016/j.thromres.2020.07.051. Epub 2020 Aug 3. Thromb Res. 2020. PMID: 32819724 Review.
The deficiency or abnormal activity of von Willebrand factor, a multi-adhesive protein which binds platelets to exposed subendothelium and carries factor VIII in circulation, is responsible for von Willebrand disease, the most freq …
The deficiency or abnormal activity of von Willebrand factor, a multi-adhesive protein which binds platelets to …
Newborn haemostasis.
Montgomery RR, Marlar RA, Gill JC. Montgomery RR, et al. Clin Haematol. 1985 Jun;14(2):443-60. Clin Haematol. 1985. PMID: 3899442 Review.
Newborn infants are at risk for developing haemorrhage or thrombosis when provoked by various pathological stimuli. Haemostasis screening tests and factor assays must be interpreted using gestational age-specific normal ranges. Frequently, the comparison of several fact …
Newborn infants are at risk for developing haemorrhage or thrombosis when provoked by various pathological stimuli. Haemostasis screening te …
Genetic regulation of plasma von Willebrand factor levels in health and disease.
Swystun LL, Lillicrap D. Swystun LL, et al. J Thromb Haemost. 2018 Dec;16(12):2375-2390. doi: 10.1111/jth.14304. Epub 2018 Oct 30. J Thromb Haemost. 2018. PMID: 30246494 Free PMC article. Review.
Plasma levels of the multimeric glycoprotein von Willebrand factor (VWF) constitute a complex quantitative trait with a continuous distribution and wide range in the normal population (50-200%). ...Quantitative trait loci influencing VWF glycosylation, secret …
Plasma levels of the multimeric glycoprotein von Willebrand factor (VWF) constitute a complex quantitative trait with a …
Inherited bleeding disorders.
Blanchette VS, Sparling C, Turner C. Blanchette VS, et al. Baillieres Clin Haematol. 1991 Apr;4(2):291-332. doi: 10.1016/s0950-3536(05)80162-3. Baillieres Clin Haematol. 1991. PMID: 1912663 Review.
Congenital bleeding disorders comprise a heterogeneous group of diseases that reflect abnormalities of blood vessels, coagulation proteins and platelets. ...Examples of the former include severe deficiencies of factors VIII and IX, and the homozygous forms of fac …
Congenital bleeding disorders comprise a heterogeneous group of diseases that reflect abnormalities of blood vessels, coagulat …
Thrombotic thrombocytopenic purpura.
Lämmle B, Kremer Hovinga JA, Alberio L. Lämmle B, et al. J Thromb Haemost. 2005 Aug;3(8):1663-75. doi: 10.1111/j.1538-7836.2005.01425.x. J Thromb Haemost. 2005. PMID: 16102032 Free article. Review.
This overview summarizes the history of thrombotic thrombocytopenic purpura (TTP) from its initial recognition in 1924 as a most often fatal disease to the discovery in 1997 of ADAMTS-13 deficiency as a major risk factor for acute disease manifestation. The cloning of the …
This overview summarizes the history of thrombotic thrombocytopenic purpura (TTP) from its initial recognition in 1924 as a most often fatal …
742 results