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Quoted phrase not found in phrase index: "Acute myeloid leukemia with CEBPA somatic mutations"
Page 1
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
Patel JP, Gönen M, Figueroa ME, Fernandez H, Sun Z, Racevskis J, Van Vlierberghe P, Dolgalev I, Thomas S, Aminova O, Huberman K, Cheng J, Viale A, Socci ND, Heguy A, Cherry A, Vance G, Higgins RR, Ketterling RP, Gallagher RE, Litzow M, van den Brink MR, Lazarus HM, Rowe JM, Luger S, Ferrando A, Paietta E, Tallman MS, Melnick A, Abdel-Wahab O, Levine RL. Patel JP, et al. N Engl J Med. 2012 Mar 22;366(12):1079-89. doi: 10.1056/NEJMoa1112304. Epub 2012 Mar 14. N Engl J Med. 2012. PMID: 22417203 Free PMC article.
BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The prognostic value of recently identified somatic mutations has not been systematically evaluated in a phase 3 trial …
BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. …
Molecular therapy for acute myeloid leukaemia.
Coombs CC, Tallman MS, Levine RL. Coombs CC, et al. Nat Rev Clin Oncol. 2016 May;13(5):305-18. doi: 10.1038/nrclinonc.2015.210. Epub 2015 Dec 1. Nat Rev Clin Oncol. 2016. PMID: 26620272 Free PMC article. Review.
Acute myeloid leukaemia (AML) is a heterogeneous disease that is, in general, associated with a very poor prognosis. ...Advances in sequencing technology have led to the discovery of novel somatic mutations in tissue samples from patients with A …
Acute myeloid leukaemia (AML) is a heterogeneous disease that is, in general, associated with a very poor prognosis. .. …
Adult acute leukemia.
Cornell RF, Palmer J. Cornell RF, et al. Dis Mon. 2012 Apr;58(4):219-38. doi: 10.1016/j.disamonth.2012.01.011. Dis Mon. 2012. PMID: 22449370 Review. No abstract available.
Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA).
Brown AL, Hahn CN, Scott HS. Brown AL, et al. Blood. 2020 Jul 2;136(1):24-35. doi: 10.1182/blood.2019000937. Blood. 2020. PMID: 32430494 Free PMC article. Review.
Recognition that germline mutations can predispose individuals to blood cancers, often presenting as secondary leukemias, has largely been driven in the last 20 years by studies of families with inherited mutations in the myeloid transcription factors (TFs) R …
Recognition that germline mutations can predispose individuals to blood cancers, often presenting as secondary leukemias, has largely …
Additional mutations in IDH1/2-mutated patients with acute myeloid leukemia.
Lu J, Chen M, Hua H, Qin W, Zhang R, Lu X, Chao H. Lu J, et al. Int J Lab Hematol. 2021 Dec;43(6):1483-1490. doi: 10.1111/ijlh.13648. Epub 2021 Jul 16. Int J Lab Hematol. 2021. PMID: 34270876
OBJECTIVE: Somatic mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) frequently emerge in acute myeloid leukemia (AML), but the clinical features and molecular characteristics of IDH mutational status and other coexisting m …
OBJECTIVE: Somatic mutations in isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) frequently emerge in acute myeloid …
Laboratory evaluation and prognostication among adults and children with CEBPA-mutant acute myeloid leukemia.
Mendoza H, Podoltsev NA, Siddon AJ. Mendoza H, et al. Int J Lab Hematol. 2021 Jul;43 Suppl 1:86-95. doi: 10.1111/ijlh.13517. Int J Lab Hematol. 2021. PMID: 34288448 Review.
CEBPA-mutant acute myeloid leukemia (AML) encompasses clinically and biologically distinct subtypes of AML in both adults and children. ...Germline CEBPA mutations may lead to familial biCEBPA AML after acquisition of second somatic …
CEBPA-mutant acute myeloid leukemia (AML) encompasses clinically and biologically distinct subtypes of AML in bo …
Hereditary acute myeloid leukemia associated with C-terminal CEBPA germline variants.
Harrigan AM, Trottier AM. Harrigan AM, et al. Fam Cancer. 2023 Jul;22(3):331-339. doi: 10.1007/s10689-023-00329-0. Epub 2023 Mar 6. Fam Cancer. 2023. PMID: 36879149 Review.
Acute myeloid leukemia with germline CEBPA mutation is a subtype of acute myeloid leukemia that is associated with a favorable prognosis. Most of the reported cases of acute myeloid leukemia with …
Acute myeloid leukemia with germline CEBPA mutation is a subtype of acute myeloid leukem …
Prognostic implications of gene mutations in acute myeloid leukemia with normal cytogenetics.
Gaidzik V, Döhner K. Gaidzik V, et al. Semin Oncol. 2008 Aug;35(4):346-55. doi: 10.1053/j.seminoncol.2008.04.005. Semin Oncol. 2008. PMID: 18692685 Review.
In recent years, a number of somatically acquired mutational changes have been identified in patients with acute myeloid leukemia (AML). ...In part, these gene mutations have emerged as important prognostic markers and they now all …
In recent years, a number of somatically acquired mutational changes have been identified in patients with acute mye …
Translational implications of somatic genomics in acute myeloid leukaemia.
Meyer SC, Levine RL. Meyer SC, et al. Lancet Oncol. 2014 Aug;15(9):e382-94. doi: 10.1016/S1470-2045(14)70008-7. Lancet Oncol. 2014. PMID: 25079101 Review.
Acute myeloid leukaemia (AML) is caused by acquired somatic mutations in haemopoietic progenitors. ...Chromosomal aberrations are known to drive AML and are the mainstay of risk classification. Mutations in FLT3, NPM1, and CEBPA provide …
Acute myeloid leukaemia (AML) is caused by acquired somatic mutations in haemopoietic progenitors. ...Chromosoma …
Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
Odenike O, Thirman MJ, Artz AS, Godley LA, Larson RA, Stock W. Odenike O, et al. Semin Oncol. 2011 Apr;38(2):196-214. doi: 10.1053/j.seminoncol.2011.01.010. Semin Oncol. 2011. PMID: 21421110 Review.
Myeloid neoplasms are characterized by acquired somatic mutations and epigenetic alterations in genes that are crucial for hematopoietic differentiation and cellular proliferation and survival pathways. ...This review will focus on common mutations tha …
Myeloid neoplasms are characterized by acquired somatic mutations and epigenetic alterations in genes that are crucial …
31 results