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Quoted phrase not found in phrase index: "Adult kidney Wilms tumor"
Page 1
Alternative RNA splicing defects in pediatric cancers: new insights in tumorigenesis and potential therapeutic vulnerabilities.
Venkataramany AS, Schieffer KM, Lee K, Cottrell CE, Wang PY, Mardis ER, Cripe TP, Chandler DS. Venkataramany AS, et al. Ann Oncol. 2022 Jun;33(6):578-592. doi: 10.1016/j.annonc.2022.03.011. Epub 2022 Mar 23. Ann Oncol. 2022. PMID: 35339647 Free article. Review.
BACKGROUND: Compared with adult cancers, pediatric cancers are uniquely characterized by a genomically stable landscape and lower tumor mutational burden. ...RESULTS: Published dysregulated splicing events can be categorized as exon inclusion, exon exclusion, splici …
BACKGROUND: Compared with adult cancers, pediatric cancers are uniquely characterized by a genomically stable landscape and lower …
Genetics of pediatric renal tumors.
Royer-Pokora B. Royer-Pokora B. Pediatr Nephrol. 2013 Jan;28(1):13-23. doi: 10.1007/s00467-012-2146-4. Epub 2012 Mar 30. Pediatr Nephrol. 2013. PMID: 22461142 Review.
Wilms tumor (WT) accounts for approximately 95 % of all pediatric renal tumors, with a peak incidence between 2 and 3 years of age. It occurs in sporadic and congenital forms, the latter often occurring before 1 year of age. Incidence declines with age, and WT rarel …
Wilms tumor (WT) accounts for approximately 95 % of all pediatric renal tumors, with a peak incidence between 2 and 3 years of …
Clinical Assessment of Late Health Outcomes in Survivors of Wilms Tumor.
Foster KL, Salehabadi SM, Green DM, Xing M, Ness KK, Krull KR, Brinkman TM, Ehrhardt MJ, Chemaitilly W, Dixon SB, Bhakta N, Brennan RC, Krasin MJ, Davidoff AM, Robison LL, Hudson MM, Mulrooney DA. Foster KL, et al. Pediatrics. 2022 Nov 1;150(5):e2022056918. doi: 10.1542/peds.2022-056918. Pediatrics. 2022. PMID: 36300342 Free PMC article.
OBJECTIVES: We aimed to clinically characterize the health, neurocognitive, and physical function outcomes of curative treatment of Wilms tumor. METHODS: Survivors of Wilms tumor (n = 280) participating in the St. ...CONCLUSIONS: Wilms tumor …
OBJECTIVES: We aimed to clinically characterize the health, neurocognitive, and physical function outcomes of curative treatment of Wilms …
Lessons from our children.
Donaldson SS. Donaldson SS. Int J Radiat Oncol Biol Phys. 1993 Aug 1;26(5):739-49. doi: 10.1016/0360-3016(93)90487-g. Int J Radiat Oncol Biol Phys. 1993. PMID: 8344841 Free article. Review.
Specific pediatric cancers, such as retinoblastoma, have led to the recognition of tumor suppressor genes, now also observed among adult tumors including sarcomas, breast, lung, and bladder cancer. ...However, 53% of all children with cancer, but only 2% of a …
Specific pediatric cancers, such as retinoblastoma, have led to the recognition of tumor suppressor genes, now also observed a …
Development and Validation of a Prediction Model for Kidney Failure in Long-Term Survivors of Childhood Cancer.
Wu NL, Chen Y, Dieffenbach BV, Ehrhardt MJ, Hingorani S, Howell RM, Jefferies JL, Mulrooney DA, Oeffinger KC, Robison LL, Weil BR, Yuan Y, Yasui Y, Hudson MM, Leisenring WM, Armstrong GT, Chow EJ. Wu NL, et al. J Clin Oncol. 2023 Apr 20;41(12):2258-2268. doi: 10.1200/JCO.22.01926. Epub 2023 Feb 16. J Clin Oncol. 2023. PMID: 36795981 Free PMC article.
Regression coefficient estimates were converted to integer risk scores. The St Jude Lifetime Cohort Study and the National Wilms Tumor Study served as validation cohorts. ...Validation cohort AUC and C-statistics were 0.88/0.88 for the St Jude Lifetime Cohort …
Regression coefficient estimates were converted to integer risk scores. The St Jude Lifetime Cohort Study and the National Wilms …
Renal function in patients with Wilms tumor.
Romao RL, Lorenzo AJ. Romao RL, et al. Urol Oncol. 2016 Jan;34(1):33-41. doi: 10.1016/j.urolonc.2015.07.002. Epub 2015 Aug 13. Urol Oncol. 2016. PMID: 26278364 Review.
Survival in patients with Wilms tumor (WT) is excellent compared with other pediatric malignancies and adult renal tumors. ...Renal dysfunction is an example of one of the most feared long-term issues observed in these survivors. Direct toxicity from c …
Survival in patients with Wilms tumor (WT) is excellent compared with other pediatric malignancies and adult renal tumo …
HOXB2 and FOXC1 synergistically drive the progression of Wilms tumor.
Jing P, Zou J, Zhang L, Wang C, Yang Y, Deng L, Zhao D. Jing P, et al. Exp Mol Pathol. 2020 Aug;115:104469. doi: 10.1016/j.yexmp.2020.104469. Epub 2020 May 21. Exp Mol Pathol. 2020. PMID: 32445751
OBJECTIVE: To uncover the expression patterns of HOXB2 and FOXC1 in Wilms tumor samples, and their synergistical regulations on the development of Wilms tumor. ...The positive interaction between HOXB2 and FOXC1 was identified, which synergistically dr …
OBJECTIVE: To uncover the expression patterns of HOXB2 and FOXC1 in Wilms tumor samples, and their synergistical regulations o …
The non-neoplastic kidney in tumor nephrectomy specimens: what can it show and what is important?
Bonsib SM, Pei Y. Bonsib SM, et al. Adv Anat Pathol. 2010 Jul;17(4):235-50. doi: 10.1097/PAP.0b013e3181e3c02d. Adv Anat Pathol. 2010. PMID: 20574169 Review.
Surgical nephrectomy is a procedure that has been performed for nearly 100 years. In the presence of a normal contralateral kidney, such as in a renal transplant donor or child with Wilms tumor, it is a benign procedure without deleterious consequences on the …
Surgical nephrectomy is a procedure that has been performed for nearly 100 years. In the presence of a normal contralateral kidney, s …
Wilms tumor reveals DNA repair gene hyperexpression is linked to lack of tumor immune infiltration.
Higgs EF, Bao R, Hatogai K, Gajewski TF. Higgs EF, et al. J Immunother Cancer. 2022 Jun;10(6):e004797. doi: 10.1136/jitc-2022-004797. J Immunother Cancer. 2022. PMID: 35705315 Free PMC article.
RESULTS: Among the four pediatric cancers, we observed the lowest TIS scores in Wilms tumor. TIS scores were lower in Wilms tumors compared with matched normal kidney tissues, arguing for loss of endogenous T cell infiltration. ... …
RESULTS: Among the four pediatric cancers, we observed the lowest TIS scores in Wilms tumor. TIS scores w …
Clinical Care for People Who Survive Childhood Cancer: A Review.
Bhatia S, Tonorezos ES, Landier W. Bhatia S, et al. JAMA. 2023 Sep 26;330(12):1175-1186. doi: 10.1001/jama.2023.16875. JAMA. 2023. PMID: 37750876 Review.
By 45 years of age, approximately 95% of people who survive childhood cancer will develop a significant health problem related to the childhood cancer diagnosis or its treatment. OBSERVATIONS: Approximately 500 000 people currently alive in the US have survived childhood c …
By 45 years of age, approximately 95% of people who survive childhood cancer will develop a significant health problem related to the childh …
575 results