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Quoted phrase not found in phrase index: "Advanced Undifferentiated Pleomorphic Sarcoma"
Page 1
Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial.
Tawbi HA, Burgess M, Bolejack V, Van Tine BA, Schuetze SM, Hu J, D'Angelo S, Attia S, Riedel RF, Priebat DA, Movva S, Davis LE, Okuno SH, Reed DR, Crowley J, Butterfield LH, Salazar R, Rodriguez-Canales J, Lazar AJ, Wistuba II, Baker LH, Maki RG, Reinke D, Patel S. Tawbi HA, et al. Lancet Oncol. 2017 Nov;18(11):1493-1501. doi: 10.1016/S1470-2045(17)30624-1. Epub 2017 Oct 4. Lancet Oncol. 2017. PMID: 28988646 Free PMC article. Clinical Trial.
BACKGROUND: Patients with advanced sarcomas have a poor prognosis and few treatment options that improve overall survival. ...Median follow-up was 17.8 months (IQR 12.3-19.3). Seven (18%) of 40 patients with soft-tissue sarcoma had an objective response, incl …
BACKGROUND: Patients with advanced sarcomas have a poor prognosis and few treatment options that improve overall survival. ... …
Options for treating different soft tissue sarcoma subtypes.
Ray-Coquard I, Serre D, Reichardt P, Martín-Broto J, Bauer S. Ray-Coquard I, et al. Future Oncol. 2018 May;14(10s):25-49. doi: 10.2217/fon-2018-0076. Future Oncol. 2018. PMID: 29768052 Review.
Management of soft tissue sarcoma is increasingly subtype-dependent. Surgery is recommended for uterine leiomyosarcoma, with trabectedin being the preferred option for advanced disease when the treatment goal is long-term tumor stabilization. ...At the cytogenetic l …
Management of soft tissue sarcoma is increasingly subtype-dependent. Surgery is recommended for uterine leiomyosarcoma, with trabecte …
Primary undifferentiated pleomorphic sarcoma in oral-maxillary area: retrospective study and molecular analysis.
You Y, Shi R, Dai M, Du Z, Tian Z, Xu G, Wang L, Wang Y, Xiao M. You Y, et al. Histol Histopathol. 2021 Aug;36(8):889-898. doi: 10.14670/HH-18-359. Epub 2021 Jul 20. Histol Histopathol. 2021. PMID: 34282850
Undifferentiated pleomorphic sarcoma (UPS) in oral-maxillary area is rarely reported. ...The rapidly progressive UPS can easily develop to an advanced and life-threatening stage, especially concerning the complex anatomical structures and spaces in the
Undifferentiated pleomorphic sarcoma (UPS) in oral-maxillary area is rarely reported. ...The rapidly progressive UPS ca
Rapalink-1 and Hydroxychloroquine Exhibit an Additive Effect in Undifferentiated Pleomorphic Sarcoma by Inducing Apoptosis.
Negayama T, Ishibashi Y, Nakamura O, Nomura Y, Kaji Y, Yamamoto T. Negayama T, et al. Anticancer Res. 2021 Oct;41(10):4885-4894. doi: 10.21873/anticanres.15302. Anticancer Res. 2021. PMID: 34593436
BACKGROUND/AIM: Advanced undifferentiated pleomorphic sarcoma (UPS) has a poor prognosis and there are few treatments that can improve overall survival. ...
BACKGROUND/AIM: Advanced undifferentiated pleomorphic sarcoma (UPS) has a poor prognosis and there are fe …
Sex-dependent Prognosis of Patients with Advanced Soft Tissue Sarcoma.
Pan M, Zhou MY, Jiang C, Zhang Z, Bui NQ, Bien J, Siy A, Achacoso N, Solorzano AV, Tse P, Chung E, Thomas S, Habel LA, Ganjoo KN. Pan M, et al. Clin Cancer Res. 2024 Jan 17;30(2):413-419. doi: 10.1158/1078-0432.CCR-23-1990. Clin Cancer Res. 2024. PMID: 37831066 Free PMC article.
PURPOSE: To examine whether overall survival (OS) differs for male and female patients with advanced soft-tissue sarcoma (STS). EXPERIMENTAL DESIGN: The study included patients from Kaiser Permanente Northern California and Stanford Cancer Center with grade 2 and 3 …
PURPOSE: To examine whether overall survival (OS) differs for male and female patients with advanced soft-tissue sarcoma (STS) …
A League of Its Own? Established and Emerging Therapies in Undifferentiated Pleomorphic Sarcoma.
Graves L, Jeck WR, Grilley-Olson JE. Graves L, et al. Curr Treat Options Oncol. 2023 Mar;24(3):212-228. doi: 10.1007/s11864-023-01054-7. Epub 2023 Feb 2. Curr Treat Options Oncol. 2023. PMID: 36729198 Review.
Undifferentiated pleomorphic sarcoma (UPS), formerly known as malignant fibrous histiocytoma (MFH), is among the most common subtypes of STS arising in the trunk or extremities of adults. Administration of systemic chemotherapy is the pri
Undifferentiated pleomorphic sarcoma (UPS), formerly known as malignant fibrous histiocytoma (MFH)
Undifferentiated and dedifferentiated soft tissue neoplasms: Immunohistochemical surrogates for differential diagnosis.
Thway K, Fisher C. Thway K, et al. Semin Diagn Pathol. 2021 Nov;38(6):170-186. doi: 10.1053/j.semdp.2021.09.005. Epub 2021 Sep 29. Semin Diagn Pathol. 2021. PMID: 34602314 Review.
As molecular advances enable the stratification of emerging genetic subsets within USTS, particularly within undifferentiated round cell sarcomas, other groups, particularly the category of undifferentiated pleomorphic sarcomas (UPS), still remain diff …
As molecular advances enable the stratification of emerging genetic subsets within USTS, particularly within undifferentiated
Sarcomas: Immune biomarker expression and checkpoint inhibitor trials.
Zhu MMT, Shenasa E, Nielsen TO. Zhu MMT, et al. Cancer Treat Rev. 2020 Dec;91:102115. doi: 10.1016/j.ctrv.2020.102115. Epub 2020 Oct 20. Cancer Treat Rev. 2020. PMID: 33130422 Free article. Review.
Each of the immune biomarkers assessed was reviewed for subtype-specific expression patterns and correlation with prognosis. Overall, there is extensive heterogeneity of immune biomarker presence across sarcoma subtypes, and no consensus on the prognostic eff …
Each of the immune biomarkers assessed was reviewed for subtype-specific expression patterns and correlation with prognosis. Overall, …
Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma.
Fuller AM, DeVine A, Murazzi I, Mason NJ, Weber K, Eisinger-Mathason TSK. Fuller AM, et al. Cell Oncol (Dordr). 2022 Dec;45(6):1277-1295. doi: 10.1007/s13402-022-00717-1. Epub 2022 Oct 1. Cell Oncol (Dordr). 2022. PMID: 36181640 Free PMC article.
PURPOSE: Undifferentiated pleomorphic sarcoma (UPS), an aggressive subtype of soft-tissue sarcoma (STS), is exceedingly rare in humans and lacks effective, well-tolerated therapies. ...RESULTS: We found that the DNA methyltransferase DNMT3B is overexpr …
PURPOSE: Undifferentiated pleomorphic sarcoma (UPS), an aggressive subtype of soft-tissue sarcoma (STS), is exce …
Neutrophil-to-Lymphocyte ratio as a prognostic biomarker in extremities undifferentiated pleomorphic sarcoma.
García-Ortega DY, Melendez-Fernandez AP, Alvarez-Cano A, Clara-Altamirano MA, Caro-Sanchez C, Alamilla-Garcia G, Luna-Ortiz K. García-Ortega DY, et al. Surg Oncol. 2022 Jun;42:101746. doi: 10.1016/j.suronc.2022.101746. Epub 2022 Mar 29. Surg Oncol. 2022. PMID: 35378375
In this paper we analyzed the prognostic role of the neutrophil to lymphocyte ratio (NLR) in extremity undifferentiated pleomorphic sarcoma (eUPS). ...Soft tissue sarcomas lack routine biomarkers that are applied widely, therefore we propose to conside …
In this paper we analyzed the prognostic role of the neutrophil to lymphocyte ratio (NLR) in extremity undifferentiated ple
90 results