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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1969 2
1970 2
1971 1
1973 1
1974 3
1975 9
1976 16
1977 7
1978 12
1979 18
1980 11
1981 19
1982 27
1983 18
1984 28
1985 26
1986 18
1987 17
1988 14
1989 33
1990 28
1991 30
1992 45
1993 43
1994 47
1995 42
1996 51
1997 60
1998 63
1999 63
2000 84
2001 85
2002 79
2003 100
2004 91
2005 110
2006 108
2007 124
2008 132
2009 156
2010 180
2011 192
2012 257
2013 274
2014 284
2015 317
2016 345
2017 380
2018 334
2019 390
2020 464
2021 550
2022 506
2023 476
2024 203

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6,123 results

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Quoted phrase not found in phrase index: "Advanced Malignant Skin Neoplasm"
Page 1
Melanoma.
Schadendorf D, van Akkooi ACJ, Berking C, Griewank KG, Gutzmer R, Hauschild A, Stang A, Roesch A, Ugurel S. Schadendorf D, et al. Lancet. 2018 Sep 15;392(10151):971-984. doi: 10.1016/S0140-6736(18)31559-9. Lancet. 2018. PMID: 30238891 Review.
Over the past 10 years, increased biological understanding and access to innovative therapeutic substances have transformed advanced melanoma into a new oncological model for treating solid cancers. Treatments that target B-Raf proto-oncogene serine/threonine-kinase (BRAF) …
Over the past 10 years, increased biological understanding and access to innovative therapeutic substances have transformed advanced …
Basal Cell Carcinoma.
Heath MS, Bar A. Heath MS, et al. Dermatol Clin. 2023 Jan;41(1):13-21. doi: 10.1016/j.det.2022.07.005. Epub 2022 Oct 28. Dermatol Clin. 2023. PMID: 36410973 Review.
Radiation therapy can be used in patients not amendable to surgery. Advanced and metastatic BCC can be treated with Hedgehog pathway inhibitors and other systemic agents with varying responses....
Radiation therapy can be used in patients not amendable to surgery. Advanced and metastatic BCC can be treated with Hedgehog pathway …
Overcoming Immune Evasion in Melanoma.
Eddy K, Chen S. Eddy K, et al. Int J Mol Sci. 2020 Nov 26;21(23):8984. doi: 10.3390/ijms21238984. Int J Mol Sci. 2020. PMID: 33256089 Free PMC article. Review.
Melanoma is the most aggressive and dangerous form of skin cancer that develops from transformed melanocytes. It is crucial to identify melanoma at its early stages, in situ, as it is "curable" at this stage. ...In recent years, a better understanding of the etiology of me …
Melanoma is the most aggressive and dangerous form of skin cancer that develops from transformed melanocytes. It is crucial to identi …
Aetiology and Pathogenesis of Cutaneous Melanoma: Current Concepts and Advances.
Strashilov S, Yordanov A. Strashilov S, et al. Int J Mol Sci. 2021 Jun 15;22(12):6395. doi: 10.3390/ijms22126395. Int J Mol Sci. 2021. PMID: 34203771 Free PMC article. Review.
Melanoma develops from malignant transformations of the pigment-producing melanocytes. If located in the basal layer of the skin epidermis, melanoma is referred to as cutaneous, which is more frequent. ...
Melanoma develops from malignant transformations of the pigment-producing melanocytes. If located in the basal layer of the skin …
Update of advanced cutaneous squamous cell carcinoma.
de Jong E, Lammerts MUPA, Genders RE, Bouwes Bavinck JN. de Jong E, et al. J Eur Acad Dermatol Venereol. 2022 Jan;36 Suppl 1(Suppl 1):6-10. doi: 10.1111/jdv.17728. J Eur Acad Dermatol Venereol. 2022. PMID: 34855246 Free PMC article. Review.
Although over 90% of the cSCC show a relatively harmless clinical behaviour, there is also a chance of developing advanced cSCC and metastases. Locally advanced cSCC are defined as cSCC that have locally advanced progression and are no longer amenable to surg …
Although over 90% of the cSCC show a relatively harmless clinical behaviour, there is also a chance of developing advanced cSCC and m …
The 2018 World Health Organization Classification of Cutaneous, Mucosal, and Uveal Melanoma: Detailed Analysis of 9 Distinct Subtypes Defined by Their Evolutionary Pathway.
Elder DE, Bastian BC, Cree IA, Massi D, Scolyer RA. Elder DE, et al. Arch Pathol Lab Med. 2020 Apr;144(4):500-522. doi: 10.5858/arpa.2019-0561-RA. Epub 2020 Feb 14. Arch Pathol Lab Med. 2020. PMID: 32057276 Free article. Review.
CONTEXT.-: There have been major advances in the understanding of melanoma since the last revision of the World Health Organization (WHO) classification in 2006. ...Melanomas on the sun-exposed skin were further divided by the histopathologic degree of cumulative so …
CONTEXT.-: There have been major advances in the understanding of melanoma since the last revision of the World Health Organization ( …
Treatment of Advanced Melanoma in 2020 and Beyond.
Jenkins RW, Fisher DE. Jenkins RW, et al. J Invest Dermatol. 2021 Jan;141(1):23-31. doi: 10.1016/j.jid.2020.03.943. Epub 2020 Apr 5. J Invest Dermatol. 2021. PMID: 32268150 Free PMC article. Review.
The melanoma field has seen an unprecedented set of clinical advances over the past decade. Therapeutic efficacy for advanced or metastatic melanoma went from being one of the most poorly responsive to one of the more responsive. Perhaps most strikingly, the adva …
The melanoma field has seen an unprecedented set of clinical advances over the past decade. Therapeutic efficacy for advanced …
Advances in cutaneous squamous cell carcinoma.
Winge MCG, Kellman LN, Guo K, Tang JY, Swetter SM, Aasi SZ, Sarin KY, Chang ALS, Khavari PA. Winge MCG, et al. Nat Rev Cancer. 2023 Jul;23(7):430-449. doi: 10.1038/s41568-023-00583-5. Epub 2023 Jun 7. Nat Rev Cancer. 2023. PMID: 37286893 Review.
Recent studies have identified subpopulations of SCC cells that specifically interact with the tumour microenvironment. These advances, along with increased knowledge of the impact of germline genetics and somatic mutations on cSCC development, have led to a greater apprec …
Recent studies have identified subpopulations of SCC cells that specifically interact with the tumour microenvironment. These advances …
Cutaneous Melanoma-A Review in Detection, Staging, and Management.
Hartman RI, Lin JY. Hartman RI, et al. Hematol Oncol Clin North Am. 2019 Feb;33(1):25-38. doi: 10.1016/j.hoc.2018.09.005. Hematol Oncol Clin North Am. 2019. PMID: 30497675 Review.
Recent changes in staging emphasize continued use of sentinel lymph node biopsy to aid in prognostication although routine complete lymph node dissection has fallen out of favor. Advances in systemic treatment options, including targeted and immunotherapy, have dramaticall …
Recent changes in staging emphasize continued use of sentinel lymph node biopsy to aid in prognostication although routine complete lymph no …
Adjuvant Dabrafenib plus Trametinib in Stage III BRAF-Mutated Melanoma.
Long GV, Hauschild A, Santinami M, Atkinson V, Mandalà M, Chiarion-Sileni V, Larkin J, Nyakas M, Dutriaux C, Haydon A, Robert C, Mortier L, Schachter J, Schadendorf D, Lesimple T, Plummer R, Ji R, Zhang P, Mookerjee B, Legos J, Kefford R, Dummer R, Kirkwood JM. Long GV, et al. N Engl J Med. 2017 Nov 9;377(19):1813-1823. doi: 10.1056/NEJMoa1708539. Epub 2017 Sep 10. N Engl J Med. 2017. PMID: 28891408 Free article. Clinical Trial.
BACKGROUND: Combination therapy with the BRAF inhibitor dabrafenib plus the MEK inhibitor trametinib improved survival in patients with advanced melanoma with BRAF V600 mutations. We sought to determine whether adjuvant dabrafenib plus trametinib would improve outcomes in …
BACKGROUND: Combination therapy with the BRAF inhibitor dabrafenib plus the MEK inhibitor trametinib improved survival in patients with a …
6,123 results