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Table representation of search results timeline featuring number of search results per year.

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1984 1
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2008 1
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2017 4
2018 2
2019 1
2021 2
2024 1

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15 results

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Page 1
Pharmacogenomics of GPCR Drug Targets.
Hauser AS, Chavali S, Masuho I, Jahn LJ, Martemyanov KA, Gloriam DE, Babu MM. Hauser AS, et al. Cell. 2018 Jan 11;172(1-2):41-54.e19. doi: 10.1016/j.cell.2017.11.033. Epub 2017 Dec 14. Cell. 2018. PMID: 29249361 Free PMC article.
We experimentally show that certain variants of mu-opioid and Cholecystokinin-A receptors could lead to altered or adverse drug response. By analyzing UK National Health Service drug prescription and sales data, we suggest that characterizing GPCR variants co …
We experimentally show that certain variants of mu-opioid and Cholecystokinin-A receptors could lead to altered or adverse drug …
Reverse Translational Research of ABCG2 (BCRP) in Human Disease and Drug Response.
Brackman DJ, Giacomini KM. Brackman DJ, et al. Clin Pharmacol Ther. 2018 Feb;103(2):233-242. doi: 10.1002/cpt.903. Epub 2017 Nov 28. Clin Pharmacol Ther. 2018. PMID: 29023674 Free PMC article. Review.
Reverse translational research takes a bedside-to-bench approach, using sophisticated basic research to explain the biological mechanisms behind observed clinical data. For transporters, which play a role in human disease and drug response, this approach offers a distinct …
Reverse translational research takes a bedside-to-bench approach, using sophisticated basic research to explain the biological mechanisms be …
Genetics of migraine and pharmacogenomics: some considerations.
Piane M, Lulli P, Farinelli I, Simeoni S, De Filippis S, Patacchioli FR, Martelletti P. Piane M, et al. J Headache Pain. 2007 Dec;8(6):334-9. doi: 10.1007/s10194-007-0427-2. Epub 2007 Dec 5. J Headache Pain. 2007. PMID: 18058067 Free PMC article. Review.
Patients with migraine respond differently to a given drug administered. The efficacy of therapy and the occurrence of adverse drug response are a consequence of individual variability. ...The development of International Hap Map project could provide a power …
Patients with migraine respond differently to a given drug administered. The efficacy of therapy and the occurrence of adverse dru …
Expectations, validity, and reality in pharmacogenetics.
Limdi NA, Veenstra DL. Limdi NA, et al. J Clin Epidemiol. 2010 Sep;63(9):960-9. doi: 10.1016/j.jclinepi.2009.09.006. Epub 2009 Dec 7. J Clin Epidemiol. 2010. PMID: 19995676 Free PMC article. Review.
In this review, we discuss the potential expectations, validity, predictive ability, and reality of pharmacogenetics in (1) titration of medication dose, (2) prediction of intended (efficacy) drug response, and (3) dose prediction of unintended (adverse) drug res …
In this review, we discuss the potential expectations, validity, predictive ability, and reality of pharmacogenetics in (1) titration of med …
Understanding drug-induced torsades de pointes: a genetic stance.
Kannankeril PJ. Kannankeril PJ. Expert Opin Drug Saf. 2008 May;7(3):231-9. doi: 10.1517/14740338.7.3.231. Expert Opin Drug Saf. 2008. PMID: 18462182 Review.
The post-genomic era hints at an improved understanding (and prediction) of how the gene-environment interaction produces this particular adverse drug response....
The post-genomic era hints at an improved understanding (and prediction) of how the gene-environment interaction produces this particular …
Genetic variants influencing fluoropyrimidine based-therapy and available methods to detect them.
Di Francia R, Cimino L, Berretta M. Di Francia R, et al. Eur Rev Med Pharmacol Sci. 2012 Mar;16(3):285-98. Eur Rev Med Pharmacol Sci. 2012. PMID: 22530343 Review.
A multitude of methods has been applied to assess the mutational status of these genes, without defining a golden standard for the daily diagnostic routine, so far. AIMS: Some adverse drug response due to the administration of 5-FU can be predicted through ph …
A multitude of methods has been applied to assess the mutational status of these genes, without defining a golden standard for the daily dia …
Evaluation of Batch Variations in Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes from 2 Major Suppliers.
Huo J, Kamalakar A, Yang X, Word B, Stockbridge N, Lyn-Cook B, Pang L. Huo J, et al. Toxicol Sci. 2017 Mar 1;156(1):25-38. doi: 10.1093/toxsci/kfw235. Toxicol Sci. 2017. PMID: 28031415
Patient-specific iPSC-hCMs have been proposed for personalized cardiac drug selection and adverse drug response prediction; however, many procedures are involved in cardiomyocytes differentiation and purification process, which may result in large line-to-lin …
Patient-specific iPSC-hCMs have been proposed for personalized cardiac drug selection and adverse drug response predict …
Efficacy and Safety Evaluation After Conversion From Twice-Daily to Once-Daily Tacrolimus in Stable Liver Transplant Recipients: A Phase 4, Open-Label, Single-Center Study.
Kang WH, Song GW, Moon DB, Hwang S, Kim KH, Jung DH, Park GC, Yoon YI, Cho HD, Kim M, Kim SH, Na BG, Kim SM, Yang G, Lee SG. Kang WH, et al. Transplant Proc. 2021 Dec;53(10):3000-3006. doi: 10.1016/j.transproceed.2021.09.043. Epub 2021 Nov 11. Transplant Proc. 2021. PMID: 34776265 Clinical Trial.
There were 37 adverse reactions after conversion; most of them were mild, and thrombocytopenia developed in 1 patient as an adverse drug response. Drug compliance improved after conversion according to questionnaire responses. ...
There were 37 adverse reactions after conversion; most of them were mild, and thrombocytopenia developed in 1 patient as an adverse …
OCT1 genetic variants are associated with postoperative morphine-related adverse effects in children.
Balyan R, Zhang X, Chidambaran V, Martin LJ, Mizuno T, Fukuda T, Vinks AA, Sadhasivam S. Balyan R, et al. Pharmacogenomics. 2017 May;18(7):621-629. doi: 10.2217/pgs-2017-0002. Epub 2017 May 4. Pharmacogenomics. 2017. PMID: 28470102 Free PMC article.
Respiratory depression (RD) and postoperative nausea and vomiting (PONV) are significant adverse drug response of intravenous morphine in the perioperative setting limiting its efficacy in achieving adequate surgical pain relief. ...METHODS: After obtaining i …
Respiratory depression (RD) and postoperative nausea and vomiting (PONV) are significant adverse drug response of intra …
A Routine over the Counter Phenylephrine Causing Rarer Drug Eruption as Adverse Drug Reaction - A Case Report.
Yella SST, Krishna Sasanka KSBS, Singh H, Meena B. Yella SST, et al. Curr Drug Saf. 2024;19(2):291-294. doi: 10.2174/1574886318666230601162144. Curr Drug Saf. 2024. PMID: 37264618
CASE PRESENTATION: Here we discuss a case of a 19-year-old female patient who reported to our hospital with blebs on the skin throughout her legs and torso. The drug eruption or adverse drug response was linked with itching, had a slow beginning, and progress …
CASE PRESENTATION: Here we discuss a case of a 19-year-old female patient who reported to our hospital with blebs on the skin throughout her …
15 results