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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 1
1978 2
1980 5
1981 8
1982 16
1983 32
1984 51
1985 65
1986 94
1987 85
1988 90
1989 91
1990 111
1991 112
1992 89
1993 107
1994 94
1995 84
1996 72
1997 81
1998 74
1999 62
2000 51
2001 53
2002 67
2003 51
2004 48
2005 64
2006 72
2007 76
2008 58
2009 59
2010 69
2011 79
2012 83
2013 81
2014 80
2015 75
2016 75
2017 72
2018 67
2019 86
2020 93
2021 90
2022 87
2023 97
2024 48

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3,002 results

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Page 1
A Review of Alprazolam Use, Misuse, and Withdrawal.
Ait-Daoud N, Hamby AS, Sharma S, Blevins D. Ait-Daoud N, et al. J Addict Med. 2018 Jan/Feb;12(1):4-10. doi: 10.1097/ADM.0000000000000350. J Addict Med. 2018. PMID: 28777203 Free PMC article. Review.
: Alprazolam is one of the most widely prescribed benzodiazepines for the treatment of generalized anxiety disorder and panic disorder. ...We have replaced it in our manuscript with "misuse liability" as it reflects a more updated terminology consistent with the Diagnostic …
: Alprazolam is one of the most widely prescribed benzodiazepines for the treatment of generalized anxiety disorder and panic disorde …
Alprazolam.
[No authors listed] [No authors listed] 2023 Jun 22. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2023 Jun 22. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643506 Free Books & Documents. Review.
Alprazolam is an orally available benzodiazepine used predominantly for therapy of anxiety. As with most benzodiazepines, alprazolam t has not been associated with serum aminotransferase or alkaline phosphatase elevations during therapy, and clinically apparent live …
Alprazolam is an orally available benzodiazepine used predominantly for therapy of anxiety. As with most benzodiazepines, alprazol …
Alprazolam: Good for Some, Not Good for All!
Mamtani H, Chaturvedi SK. Mamtani H, et al. J Clin Psychopharmacol. 2023 May-Jun 01;43(3):204-208. doi: 10.1097/JCP.0000000000001669. J Clin Psychopharmacol. 2023. PMID: 37040158 Review.
Also, the withdrawal triggered by use of alprazolam is challenging to treat. Alternate pharmacological and non-pharmacological strategies for use in anxiety and insomnia are available, which might be safer than alprazolam. Also, policy changes can serve as an answer …
Also, the withdrawal triggered by use of alprazolam is challenging to treat. Alternate pharmacological and non-pharmacological strate …
Alprazolam for tinnitus.
Huynh L, Fields S. Huynh L, et al. Ann Pharmacother. 1995 Mar;29(3):311-2. doi: 10.1177/106002809502900313. Ann Pharmacother. 1995. PMID: 7606078 Review.
There is insufficient evidence to support the use of alprazolam in the treatment of tinnitus. The Johnson trial is the only study to date assessing the role of alprazolam, and at best it is an open-label trial demonstrating activity. ...Furthermore, once efficacy is …
There is insufficient evidence to support the use of alprazolam in the treatment of tinnitus. The Johnson trial is the only study to …
Alprazolam and benzodiazepine dependence.
Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE. Sellers EM, et al. J Clin Psychiatry. 1993 Oct;54 Suppl:64-75; discussion 76-7. J Clin Psychiatry. 1993. PMID: 8262891 Review.
For example, a serious problem of alprazolam abuse may exist among patients in methadone maintenance treatment. ...In the interim, caution but not prohibition to use should prevail in prescribing alprazolam to such patients. To the extent that nonmedical alprazol …
For example, a serious problem of alprazolam abuse may exist among patients in methadone maintenance treatment. ...In the interim, ca …
Alprazolam is relatively more toxic than other benzodiazepines in overdose.
Isbister GK, O'Regan L, Sibbritt D, Whyte IM. Isbister GK, et al. Br J Clin Pharmacol. 2004 Jul;58(1):88-95. doi: 10.1111/j.1365-2125.2004.02089.x. Br J Clin Pharmacol. 2004. PMID: 15206998 Free PMC article. Review.
AIMS: To describe alprazolam poisoning and the relative toxicity of alprazolam compared with other benzodiazepines. ...Twelve percent of alprazolam overdoses had a GCS < 9 compared with 10% for other benzodiazepines. ...
AIMS: To describe alprazolam poisoning and the relative toxicity of alprazolam compared with other benzodiazepines. ...Twelve …
Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications.
Greenblatt DJ, von Moltke LL, Harmatz JS, Ciraulo DA, Shader RI. Greenblatt DJ, et al. J Clin Psychiatry. 1993 Oct;54 Suppl:4-11; discussion 12-4. J Clin Psychiatry. 1993. PMID: 8262889 Review.
The triazolobenzodiazepine alprazolam is biotransformed by hepatic microsomal oxidation, yielding two hydroxylated metabolites (4-hydroxy- and a-hydroxy-alprazolam) as the principal metabolic products. Both metabolites have lower benzodiazepine receptor affinity tha …
The triazolobenzodiazepine alprazolam is biotransformed by hepatic microsomal oxidation, yielding two hydroxylated metabolites (4-hyd …
Alprazolam and diazepam: addiction potential.
Juergens S. Juergens S. J Subst Abuse Treat. 1991;8(1-2):43-51. doi: 10.1016/0740-5472(91)90026-7. J Subst Abuse Treat. 1991. PMID: 2051498 Review.
Alprazolam and diazepam, the two most prescribed benzodiazepine anxiolytics in the United States, have potential for addictive use. ...Both drugs are rapidly absorbed and enter the brain tissue rapidly, leading to reinforcement. Alprazolam has a shorter half-life, w …
Alprazolam and diazepam, the two most prescribed benzodiazepine anxiolytics in the United States, have potential for addictive use. . …
Alprazolam: a review of its pharmacodynamic properties and efficacy in the treatment of anxiety and depression.
Dawson GW, Jue SG, Brogden RN. Dawson GW, et al. Drugs. 1984 Feb;27(2):132-47. doi: 10.2165/00003495-198427020-00002. Drugs. 1984. PMID: 6141930 Review.
Relative to the newer benzodiazepines, alprazolam has an intermediate half-life of 10 to 12 hours in healthy young subjects. ...Thus, alprazolam may be particularly useful in patients with mixed anxiety/depression. ...
Relative to the newer benzodiazepines, alprazolam has an intermediate half-life of 10 to 12 hours in healthy young subjects. ...Thus, …
Alprazolam: pharmacokinetics, clinical efficacy, and mechanism of action.
Fawcett JA, Kravitz HM. Fawcett JA, et al. Pharmacotherapy. 1982 Sep-Oct;2(5):243-54. doi: 10.1002/j.1875-9114.1982.tb03191.x. Pharmacotherapy. 1982. PMID: 6133268 Review.
Alprazolam, a triazolobenzodiazepine, is the first of this new class of benzodiazepine drugs to be marketed in the United States and Canada. ...Also undergoing investigation is the potential role of alprazolam in the treatment of panic disorders. Alprazolam h …
Alprazolam, a triazolobenzodiazepine, is the first of this new class of benzodiazepine drugs to be marketed in the United States and …
3,002 results