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2,683 results

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Quoted phrase not found in phrase index: "Alzheimer disease 18"
Page 1
Biomarker Changes during 20 Years Preceding Alzheimer's Disease.
Jia J, Ning Y, Chen M, Wang S, Yang H, Li F, Ding J, Li Y, Zhao B, Lyu J, Yang S, Yan X, Wang Y, Qin W, Wang Q, Li Y, Zhang J, Liang F, Liao Z, Wang S. Jia J, et al. N Engl J Med. 2024 Feb 22;390(8):712-722. doi: 10.1056/NEJMoa2310168. N Engl J Med. 2024. PMID: 38381674
BACKGROUND: Biomarker changes that occur in the period between normal cognition and the diagnosis of sporadic Alzheimer's disease have not been extensively investigated in longitudinal studies. ...As cognitive impairment progressed, the changes in CSF biomarker leve …
BACKGROUND: Biomarker changes that occur in the period between normal cognition and the diagnosis of sporadic Alzheimer's disease …
PET Imaging of Neuroinflammation in Alzheimer's Disease.
Zhou R, Ji B, Kong Y, Qin L, Ren W, Guan Y, Ni R. Zhou R, et al. Front Immunol. 2021 Sep 16;12:739130. doi: 10.3389/fimmu.2021.739130. eCollection 2021. Front Immunol. 2021. PMID: 34603323 Free PMC article. Review.
Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in molecular imaging using positron emission tomography have provided insights into the time course of neuroinflammation and its relation with Alzheimer's disease …
Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in molecular imaging using positron emi …
Amyloid beta deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.
Villemagne VL, Burnham S, Bourgeat P, Brown B, Ellis KA, Salvado O, Szoeke C, Macaulay SL, Martins R, Maruff P, Ames D, Rowe CC, Masters CL; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group. Villemagne VL, et al. Lancet Neurol. 2013 Apr;12(4):357-67. doi: 10.1016/S1474-4422(13)70044-9. Epub 2013 Mar 8. Lancet Neurol. 2013. PMID: 23477989
BACKGROUND: Similar to most chronic diseases, Alzheimer's disease (AD) develops slowly from a preclinical phase into a fully expressed clinical syndrome. ...INTERPRETATION: Abeta deposition is slow and protracted, likely to extend for more than two decades. Such …
BACKGROUND: Similar to most chronic diseases, Alzheimer's disease (AD) develops slowly from a preclinical phase into a fully e …
Alzheimer disease in the United States (2010-2050) estimated using the 2010 census.
Hebert LE, Weuve J, Scherr PA, Evans DA. Hebert LE, et al. Neurology. 2013 May 7;80(19):1778-83. doi: 10.1212/WNL.0b013e31828726f5. Epub 2013 Feb 6. Neurology. 2013. PMID: 23390181 Free PMC article. Clinical Trial.
OBJECTIVES: To provide updated estimates of Alzheimer disease (AD) dementia prevalence in the United States from 2010 through 2050. ...Incidence probabilities for single year of age, race, and level of education were calculated using weighted logistic regression and …
OBJECTIVES: To provide updated estimates of Alzheimer disease (AD) dementia prevalence in the United States from 2010 through …
Music therapy in moderate and severe dementia of Alzheimer's type: a case-control study.
Svansdottir HB, Snaedal J. Svansdottir HB, et al. Int Psychogeriatr. 2006 Dec;18(4):613-21. doi: 10.1017/S1041610206003206. Epub 2006 Apr 18. Int Psychogeriatr. 2006. PMID: 16618375 Clinical Trial.
METHODS: This case-control study was carried out by qualified music therapists in two nursing homes and two psychogeriatric wards. The participants were 38 patients with moderate or severe Alzheimer's disease (AD) assigned randomly to a music therapy group and a con …
METHODS: This case-control study was carried out by qualified music therapists in two nursing homes and two psychogeriatric wards. The parti …
The Association Between Eye Disease and Incidence of Dementia: Systematic Review and Meta-Analysis.
Feng J, Huang C, Liang L, Li C, Wang X, Ma J, Guan X, Jiang B, Huang S, Qin P. Feng J, et al. J Am Med Dir Assoc. 2023 Sep;24(9):1363-1373.e6. doi: 10.1016/j.jamda.2023.06.025. Epub 2023 Jul 29. J Am Med Dir Assoc. 2023. PMID: 37527793 Review.
We included cohort studies that evaluated the association of glaucoma, age-related macular degeneration (AMD), diabetic retinopathy (DR), and cataracts with all-cause dementia, Alzheimer's disease (AD), and vascular dementia (VaD). Relative risks (RRs) and 95% CIs w …
We included cohort studies that evaluated the association of glaucoma, age-related macular degeneration (AMD), diabetic retinopathy (DR), an …
Observational studies in Alzheimer disease: bridging preclinical studies and clinical trials.
Brenowitz WD, Yaffe K. Brenowitz WD, et al. Nat Rev Neurol. 2022 Dec;18(12):747-757. doi: 10.1038/s41582-022-00733-7. Epub 2022 Oct 31. Nat Rev Neurol. 2022. PMID: 36316487 Free PMC article. Review.
Recent high-profile failures of Alzheimer disease treatments at the clinical trial stage have led to renewed efforts to identify and test novel interventions for Alzheimer disease and related dementias (ADRD). ...Observational study designs can be part …
Recent high-profile failures of Alzheimer disease treatments at the clinical trial stage have led to renewed efforts to identi …
Alzheimer disease in African American individuals: increased incidence or not enough data?
Barnes LL. Barnes LL. Nat Rev Neurol. 2022 Jan;18(1):56-62. doi: 10.1038/s41582-021-00589-3. Epub 2021 Dec 6. Nat Rev Neurol. 2022. PMID: 34873310 Free PMC article. Review.
Research on racial differences in Alzheimer disease (AD) dementia has increased in recent years. Older African American individuals bear a disproportionate burden of AD and cognitive impairment compared with non-Latino white individuals. ...Therapeutic targets and e …
Research on racial differences in Alzheimer disease (AD) dementia has increased in recent years. Older African American indivi …
Multimodality imaging of Alzheimer disease and other neurodegenerative dementias.
Nasrallah IM, Wolk DA. Nasrallah IM, et al. J Nucl Med. 2014 Dec;55(12):2003-11. doi: 10.2967/jnumed.114.141416. Epub 2014 Nov 20. J Nucl Med. 2014. PMID: 25413136 Free PMC article. Review.
Neurodegenerative diseases, such as Alzheimer disease, result in cognitive decline and dementia and are a leading cause of mortality in the growing elderly population. ...Neuroimaging biomarkers-principally regional atrophy on structural MR imaging, patterns of hypo …
Neurodegenerative diseases, such as Alzheimer disease, result in cognitive decline and dementia and are a leading cause of mor …
Dementia, Alzheimer's Disease, and Mortality after Hemodialysis Initiation.
McAdams-DeMarco MA, Daubresse M, Bae S, Gross AL, Carlson MC, Segev DL. McAdams-DeMarco MA, et al. Clin J Am Soc Nephrol. 2018 Sep 7;13(9):1339-1347. doi: 10.2215/CJN.10150917. Epub 2018 Aug 9. Clin J Am Soc Nephrol. 2018. PMID: 30093374 Free PMC article.
BACKGROUND AND OBJECTIVES: Older patients with ESKD experience rapid declines in executive function after initiating hemodialysis; these impairments might lead to high rates of dementia and Alzheimer's disease in this population. We estimated incidence, risk factors …
BACKGROUND AND OBJECTIVES: Older patients with ESKD experience rapid declines in executive function after initiating hemodialysis; these imp …
2,683 results