Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1975 1
1979 1
1984 1
1986 1
1991 1
1992 1
1995 1
1996 2
1998 1
1999 2
2000 2
2001 1
2002 1
2004 2
2005 1
2006 1
2008 2
2010 2
2011 3
2012 1
2013 4
2014 1
2015 2
2016 2
2017 2
2018 3
2019 5
2020 6
2021 4
2022 3
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

57 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Amyloidosis of peripheral nerves"
Page 1
Chronic inflammatory demyelinating polyradiculoneuropathy-Diagnostic pitfalls and treatment approach.
Stino AM, Naddaf E, Dyck PJ, Dyck PJB. Stino AM, et al. Muscle Nerve. 2021 Feb;63(2):157-169. doi: 10.1002/mus.27046. Epub 2020 Sep 11. Muscle Nerve. 2021. PMID: 32914902 Free article. Review.
With the lack of a diagnostic biomarker, the diagnosis relies on clinical suspicion, clinical findings, and the demonstration of demyelinating changes on electrodiagnostic (EDx) testing and nerve pathology. ...Interpreting the EDx testing and cerebrospinal fluid fin …
With the lack of a diagnostic biomarker, the diagnosis relies on clinical suspicion, clinical findings, and the demonstration …
RNA-targeting and gene editing therapies for transthyretin amyloidosis.
Aimo A, Castiglione V, Rapezzi C, Franzini M, Panichella G, Vergaro G, Gillmore J, Fontana M, Passino C, Emdin M. Aimo A, et al. Nat Rev Cardiol. 2022 Oct;19(10):655-667. doi: 10.1038/s41569-022-00683-z. Epub 2022 Mar 23. Nat Rev Cardiol. 2022. PMID: 35322226 Review.
TTR molecules can misfold and form amyloid fibrils in the heart and peripheral nerves, either as a result of gene variants in TTR or as an ageing-related phenomenon, which can lead to amyloid TTR (ATTR) amyloidosis. ...Preliminary data show that therapy with …
TTR molecules can misfold and form amyloid fibrils in the heart and peripheral nerves, either as a result of gene variants in …
Safety and efficacy of RNAi therapy for transthyretin amyloidosis.
Coelho T, Adams D, Silva A, Lozeron P, Hawkins PN, Mant T, Perez J, Chiesa J, Warrington S, Tranter E, Munisamy M, Falzone R, Harrop J, Cehelsky J, Bettencourt BR, Geissler M, Butler JS, Sehgal A, Meyers RE, Chen Q, Borland T, Hutabarat RM, Clausen VA, Alvarez R, Fitzgerald K, Gamba-Vitalo C, Nochur SV, Vaishnaw AK, Sah DW, Gollob JA, Suhr OB. Coelho T, et al. N Engl J Med. 2013 Aug 29;369(9):819-29. doi: 10.1056/NEJMoa1208760. N Engl J Med. 2013. PMID: 23984729 Free article. Clinical Trial.
BACKGROUND: Transthyretin amyloidosis is caused by the deposition of hepatocyte-derived transthyretin amyloid in peripheral nerves and the heart. ...Each formulation was studied in a single-dose, placebo-controlled phase 1 trial to assess safety and ef …
BACKGROUND: Transthyretin amyloidosis is caused by the deposition of hepatocyte-derived transthyretin amyloid in peripheral …
Familial amyloid polyneuropathy.
Barreiros AP, Galle PR, Otto G. Barreiros AP, et al. Dig Dis. 2013;31(1):170-4. doi: 10.1159/000347214. Epub 2013 Jun 17. Dig Dis. 2013. PMID: 23797140 Review.
Familial amyloid polyneuropathy (FAP; also known as familiar amyloidosis and hereditary amyloidosis) is an autosomal dominant inherited disease due to mutations of the transthyretin (TTR) gene coding for the corresponding protein, consisting of 127 amino acids. ...A …
Familial amyloid polyneuropathy (FAP; also known as familiar amyloidosis and hereditary amyloidosis) is an autosomal dominant …
Primary systemic amyloidosis.
Comenzo RL. Comenzo RL. Curr Treat Options Oncol. 2000 Apr;1(1):83-9. doi: 10.1007/s11864-000-0018-9. Curr Treat Options Oncol. 2000. PMID: 12057064 Review.
Patients with unexplained heart failure, hepatomegaly, nephrotic syndrome, or peripheral neuropathy should be evaluated for primary systemic (amyloid light-chain, or AL) amyloidosis by first seeking evidence of a clonal plasma cell disorder with serum and urine immu …
Patients with unexplained heart failure, hepatomegaly, nephrotic syndrome, or peripheral neuropathy should be evaluated for primary s …
The Ultrastructure of Tissue Damage by Amyloid Fibrils.
Koike H, Katsuno M. Koike H, et al. Molecules. 2021 Jul 29;26(15):4611. doi: 10.3390/molecules26154611. Molecules. 2021. PMID: 34361762 Free PMC article. Review.
Amyloidosis is a group of diseases that includes Alzheimer's disease, prion diseases, transthyretin (ATTR) amyloidosis, and immunoglobulin light chain (AL) amyloidosis. The mechanism of organ dysfunction resulting from amyloidosis has been a topic of d …
Amyloidosis is a group of diseases that includes Alzheimer's disease, prion diseases, transthyretin (ATTR) amyloidosis, and im …
Diagnosis of amyloid neuropathy.
Kapoor M, Rossor AM, Jaunmuktane Z, Lunn MPT, Reilly MM. Kapoor M, et al. Pract Neurol. 2019 Jun;19(3):250-258. doi: 10.1136/practneurol-2018-002098. Epub 2018 Dec 30. Pract Neurol. 2019. PMID: 30598431 Review.
Systemic amyloidosis can be hereditary or acquired. The autosomal dominant hereditary transthyretin amyloidosis and the acquired light-chain amyloidosis, the result of a plasma cell dyscrasia, are multisystem disorders with cardiovascular, autonomic and pe …
Systemic amyloidosis can be hereditary or acquired. The autosomal dominant hereditary transthyretin amyloidosis and the acquir …
Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm.
Sekijima Y, Ueda M, Koike H, Misawa S, Ishii T, Ando Y. Sekijima Y, et al. Orphanet J Rare Dis. 2018 Jan 17;13(1):6. doi: 10.1186/s13023-017-0726-x. Orphanet J Rare Dis. 2018. PMID: 29343286 Free PMC article. Review.
Hereditary ATTR (ATTRm) amyloidosis (also called transthyretin-type familial amyloid polyneuropathy [ATTR-FAP]) is an autosomal-dominant, adult-onset, rare systemic disorder predominantly characterized by irreversible, progressive, and persistent peripheral nerve da …
Hereditary ATTR (ATTRm) amyloidosis (also called transthyretin-type familial amyloid polyneuropathy [ATTR-FAP]) is an autosomal-domin …
Long-term efficacy and safety of inotersen for hereditary transthyretin amyloidosis: NEURO-TTR open-label extension 3-year update.
Brannagan TH, Coelho T, Wang AK, Polydefkis MJ, Dyck PJ, Berk JL, Drachman B, Gorevic P, Whelan C, Conceição I, Plante-Bordeneuve V, Merlini G, Obici L, Plana JMC, Gamez J, Kristen AV, Mazzeo A, Gentile L, Narayana A, Olugemo K, Aquino P, Benson MD, Gertz M; NEURO-T. T. R. Open-Label Extension Investigators. Brannagan TH, et al. J Neurol. 2022 Dec;269(12):6416-6427. doi: 10.1007/s00415-022-11276-8. Epub 2022 Jul 31. J Neurol. 2022. PMID: 35908242 Free PMC article.
BACKGROUND: Hereditary transthyretin amyloidosis (hATTR/ATTRv) results from the deposition of misfolded transthyretin (TTR) throughout the body, including peripheral nerves. ...
BACKGROUND: Hereditary transthyretin amyloidosis (hATTR/ATTRv) results from the deposition of misfolded transthyretin (TTR) throughou …
An evaluation of patisiran: a viable treatment option for transthyretin-related hereditary amyloidosis.
Milani P, Mussinelli R, Perlini S, Palladini G, Obici L. Milani P, et al. Expert Opin Pharmacother. 2019 Dec;20(18):2223-2228. doi: 10.1080/14656566.2019.1671352. Epub 2019 Sep 30. Expert Opin Pharmacother. 2019. PMID: 31566422 Review.
Introduction: Hereditary transthyretin-mediated amyloidosis (ATTRv; v for variant) is a rare, progressive, fatal multi-systemic disease, autosomal dominantly inherited with heterogeneous clinical phenotype caused by mutations in the TTR gene. ...This compound demons …
Introduction: Hereditary transthyretin-mediated amyloidosis (ATTRv; v for variant) is a rare, progressive, fatal multi-systemic disea …
57 results