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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 2
1979 3
1980 3
1981 6
1982 2
1983 4
1984 3
1985 2
1986 1
1987 1
1989 1
2014 1
2019 1
2020 5
2022 2
2023 1
2024 0

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37 results

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Page 1
Anti-influenza virus activities and mechanism of antrafenine analogs.
Tang YS, Zhang C, Lo CY, Jin Z, Kong BL, Xiao MJ, Huang EF, Hu C, Shaw PC. Tang YS, et al. Eur J Med Chem. 2023 Nov 15;260:115775. doi: 10.1016/j.ejmech.2023.115775. Epub 2023 Aug 28. Eur J Med Chem. 2023. PMID: 37672932
Antrafenine is a drug initially designed for anti-inflammation uses. ...In this work we identify a new class of compounds, structurally similar to the anti-inflammation drug antrafenine, with good potency against influenza A strains. The IC(50) of the best performer …
Antrafenine is a drug initially designed for anti-inflammation uses. ...In this work we identify a new class of compounds, structural …
Antrafenine, naproxen and placebo in osteoarthritis: a comparative study.
Berry H, Coquelin JP, Gordon A, Seymour D. Berry H, et al. Br J Rheumatol. 1983 May;22(2):89-94. doi: 10.1093/rheumatology/22.2.89. Br J Rheumatol. 1983. PMID: 6342700 Clinical Trial.
Antrafenine is a new non-narcotic analgesic. In a double-blind, cross-over study the efficacy of antrafenine at doses of 450 mg/day and 900 mg/day was compared to naproxen 750 mg/day and placebo in patients with osteoarthritis. ...There was no definite indication th …
Antrafenine is a new non-narcotic analgesic. In a double-blind, cross-over study the efficacy of antrafenine at doses of 450 m …
Antrafenine: anti-inflammatory activity with respect to oedema and leucocyte infiltration in the rat.
Dunn CJ, Prouteau M, Delahaye M, Purcell T, Branceni D. Dunn CJ, et al. Agents Actions. 1984 Feb;14(2):296-9. doi: 10.1007/BF01966656. Agents Actions. 1984. PMID: 6608864
Antrafenine effectively suppressed carrageenan paw oedema in the rat (ED 40 = 24 mg/kg p.o) in the dose range of 10-40 mg/kg p.o, approximating that of phenylbutazone. ...These observations suggest that antrafenine merits further investigation with respect to its an …
Antrafenine effectively suppressed carrageenan paw oedema in the rat (ED 40 = 24 mg/kg p.o) in the dose range of 10-40 mg/kg p.o, app …
A comparison of antrafenine and aspirin on platelet aggregation and frusemide-induced diuresis.
Hassan SM, Olivesi A, Fish A, Turner P. Hassan SM, et al. Postgrad Med J. 1982 Jan;58(675):17-9. doi: 10.1136/pgmj.58.675.17. Postgrad Med J. 1982. PMID: 7088753 Free PMC article. Clinical Trial.
The effects of antrafenine were compared with aspirin and placebo on platelet aggregation and on the diuretic action of frusemide in normal volunteers. Aspirin significantly reduced platelet aggregation at 3 and 6 hr after administration, but antrafenine only at 3 h …
The effects of antrafenine were compared with aspirin and placebo on platelet aggregation and on the diuretic action of frusemide in …
Determination of antrafenine and its main acid metabolite, 2-{[7-(trifluoromethyl)-4-quinolinyl]amino}-benzoic acid, in biological fluids using high-performance liquid chromatography with large volume automatic injection and gas-liquid chromatography with derivative formation.
Guinebault PR, Broquaire M, Sanjuan M, Rovei V, Braithwaite RA. Guinebault PR, et al. J Chromatogr. 1981 Apr 10;223(1):103-10. doi: 10.1016/s0378-4347(00)80072-9. J Chromatogr. 1981. PMID: 7251752
Specific and sensitive analytical methods have been developed for the measurement of antrafenine and its main acid metabolite, 2-([17-(trifluoromethyl)-4-quinolinyl] amino) benzoic acid (FQB), at therapeutic concentrations in plasma and urine. ...The coefficient of variati …
Specific and sensitive analytical methods have been developed for the measurement of antrafenine and its main acid metabolite, 2-([17 …
In-vivo metabolism in the rat and mouse of antrafenine to 1-m-trifluoromethylphenylpiperazine.
Caccia S, Conti I, Notarnicola A. Caccia S, et al. J Pharm Pharmacol. 1985 Jan;37(1):75-7. doi: 10.1111/j.2042-7158.1985.tb04940.x. J Pharm Pharmacol. 1985. PMID: 2858538
The analgesic antrafenine forms 1-m-trifluoromethylphenylpiperazine (mCF3PP) during its biotransformation in the rat and mouse. At least 14 and 3% of an antrafenine dose (25 mg kg-1 p.o.) reaches the systemic circulation as mCF3PP in the mouse and rat respectively. …
The analgesic antrafenine forms 1-m-trifluoromethylphenylpiperazine (mCF3PP) during its biotransformation in the rat and mouse. At le …
In silico identification of new inhibitors for βeta-2-glycoprotein I as a major antigen in antiphospholipid antibody syndrome.
Mahdian S, Zarrabi M, Moini A, Movahedi M, Shahhoseini M. Mahdian S, et al. J Mol Model. 2020 May 26;26(6):156. doi: 10.1007/s00894-020-04406-4. J Mol Model. 2020. PMID: 32458176
Among these drugs that had the most favorable deltaG, Vorapaxar and Antrafenine were selected for molecular dynamics (MD) simulation studies. ...According to the results, Vorapaxar and Antrafenine were bound to the protein with the favorable binding energy (Vorapaxa …
Among these drugs that had the most favorable deltaG, Vorapaxar and Antrafenine were selected for molecular dynamics (MD) simulation …
[Antrafenine in odonto-stomatology (Stakane)].
Treyssac P, Missika P. Treyssac P, et al. Rev Odontostomatol (Paris). 1978 Sep-Oct;7(5):377-8. Rev Odontostomatol (Paris). 1978. PMID: 283483 French. No abstract available.
Assessment of analgesic drugs in soft tissue injuries presenting to an accident and emergency department--a comparison of antrafenine, paracetamol and placebo.
de Gara C, Taylor M, Hedges A. de Gara C, et al. Postgrad Med J. 1982 Aug;58(682):489-92. doi: 10.1136/pgmj.58.682.489. Postgrad Med J. 1982. PMID: 6752926 Free PMC article. Clinical Trial.
In a preliminary dose-finding study in patients following abdominal hysterectomy, antrafenine was found to be an effective analgesic in single oral doses of 300-600 mg. ...The only significant difference (P<0.05) noted between drug treatments was a longer duration of an …
In a preliminary dose-finding study in patients following abdominal hysterectomy, antrafenine was found to be an effective analgesic …
37 results