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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1983 1
1985 1
1988 1
1990 2
1991 1
1992 4
1993 5
1994 5
1995 5
1996 2
1997 2
1998 4
1999 3
2000 1
2001 3
2002 3
2003 9
2004 5
2005 4
2006 6
2007 7
2008 8
2009 14
2010 9
2011 16
2012 11
2013 16
2014 23
2015 26
2016 15
2017 22
2018 17
2019 20
2020 23
2021 15
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2023 13
2024 5

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306 results

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Quoted phrase not found in phrase index: "Astrocytoma, increased risk of"
Page 1
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M. Le Rhun E, et al. Cancer Treat Rev. 2019 Nov;80:101896. doi: 10.1016/j.ctrv.2019.101896. Epub 2019 Sep 11. Cancer Treat Rev. 2019. PMID: 31541850 Free article. Review.
More than 90% of glioblastomas are isocitrate dehydrogenase (IDH)-wildtype tumors. Incidence increases with age, males are more often affected. Beyond rare instances of genetic predisposition and irradiation exposure, there are no known glioblastoma risk factors. .. …
More than 90% of glioblastomas are isocitrate dehydrogenase (IDH)-wildtype tumors. Incidence increases with age, males are more often …
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA. Keskin DB, et al. Nature. 2019 Jan;565(7738):234-239. doi: 10.1038/s41586-018-0792-9. Epub 2018 Dec 19. Nature. 2019. PMID: 30568305 Free PMC article. Clinical Trial.
Here we demonstrate that a strategy that uses multi-epitope, personalized neoantigen vaccination, which has previously been tested in patients with high-risk melanoma(4-6), is feasible for tumours such as glioblastoma, which typically have a relatively low mutation load(1, …
Here we demonstrate that a strategy that uses multi-epitope, personalized neoantigen vaccination, which has previously been tested in patien …
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ Jr, Mehta MP. Gilbert MR, et al. N Engl J Med. 2014 Feb 20;370(8):699-708. doi: 10.1056/NEJMoa1308573. N Engl J Med. 2014. PMID: 24552317 Free PMC article. Clinical Trial.
Whether the addition of bevacizumab would improve survival among patients with newly diagnosed glioblastoma is not known. METHODS: In this randomized, double-blind, placebo-controlled trial, we treated adults who had centrally confirmed glioblastoma with radiotherap …
Whether the addition of bevacizumab would improve survival among patients with newly diagnosed glioblastoma is not known. METHODS: In this …
Encephalocraniocutaneous Lipomatosis.
Bavle A, Shah R, Gross N, Gavula T, Ruiz-Elizalde A, Wierenga K, McNall-Knapp R. Bavle A, et al. J Pediatr Hematol Oncol. 2018 Oct;40(7):553-554. doi: 10.1097/MPH.0000000000001170. J Pediatr Hematol Oncol. 2018. PMID: 29683947
Magnetic resonance imaging revealed a large suprasellar mass, which was debulked and found to be a pilocytic astrocytoma. Testing was not performed for the BRAF/KIAA1549 fusion or BRAFV600E mutation. ...Targeted sequencing of tissue from the right gluteal mass, revealed a …
Magnetic resonance imaging revealed a large suprasellar mass, which was debulked and found to be a pilocytic astrocytoma. Testing was …
Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y. Su J, et al. J Transl Med. 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. J Transl Med. 2022. PMID: 36180956 Free PMC article.
Based on LASSO Cox analysis, 12 DE-MRGs were selected to construct a risk score model. Survival, time dependent ROC, and stratified analyses were performed to evaluate the performance of this risk model. ...Mechanistically, SSBP1 knockdown resulted in mitochondrial …
Based on LASSO Cox analysis, 12 DE-MRGs were selected to construct a risk score model. Survival, time dependent ROC, and stratified a …
Glioblastoma care in the elderly.
Jordan JT, Gerstner ER, Batchelor TT, Cahill DP, Plotkin SR. Jordan JT, et al. Cancer. 2016 Jan 15;122(2):189-97. doi: 10.1002/cncr.29742. Epub 2015 Nov 30. Cancer. 2016. PMID: 26618888 Free article. Review.
Although the standard of care for nonelderly patients with glioblastoma includes maximal safe surgical resection followed by radiotherapy with concurrent and adjuvant temozolomide, the safety and efficacy of these modalities in elderly patients are less certain given the populati …
Although the standard of care for nonelderly patients with glioblastoma includes maximal safe surgical resection followed by radiotherapy wi …
Glioblastoma: changing expectations?
Arribas Alpuente L, Menéndez López A, Yayá Tur R. Arribas Alpuente L, et al. Clin Transl Oncol. 2011 Apr;13(4):240-8. doi: 10.1007/s12094-011-0648-3. Clin Transl Oncol. 2011. PMID: 21493184 Review.
Lately, the knowledge of genetic information about gliomagenesis has increased; we even have a classification of the genetic expression of the tumour. ...These imaging techniques allow the radiation oncologist to better contour the irradiation target volume, the structures …
Lately, the knowledge of genetic information about gliomagenesis has increased; we even have a classification of the genetic expressi …
The effects of statin therapy on brain tumors, particularly glioma: a review.
Alrosan AZ, Heilat GB, Al Subeh ZY, Alrosan K, Alrousan AF, Abu-Safieh AK, Alabdallat NS. Alrosan AZ, et al. Anticancer Drugs. 2023 Oct 1;34(9):985-994. doi: 10.1097/CAD.0000000000001533. Epub 2023 Jul 19. Anticancer Drugs. 2023. PMID: 37466094 Free PMC article. Review.
Statins, also known as competitive HMG-CoA reductase inhibitors, are effective medications for reducing cholesterol and cardiovascular risk. The use of statins prior to and during other cancer treatments appears to enhance patient outcomes according to preclinical studies. …
Statins, also known as competitive HMG-CoA reductase inhibitors, are effective medications for reducing cholesterol and cardiovascular ri …
Epidemiology, biology, and management of venous thromboembolism in gliomas: An interdisciplinary review.
Jo J, Diaz M, Horbinski C, Mackman N, Bagley S, Broekman M, Rak J, Perry J, Pabinger I, Key NS, Schiff D. Jo J, et al. Neuro Oncol. 2023 Aug 3;25(8):1381-1394. doi: 10.1093/neuonc/noad059. Neuro Oncol. 2023. PMID: 37100086 Free PMC article.
Due to the elevated risk of intracranial hemorrhage (ICH) in GBM, anticoagulation treatment remains challenging and at times fraught. There are conflicting data on the risk of ICH with LMWH in patients with glioma; small retrospective studies suggest D …
Due to the elevated risk of intracranial hemorrhage (ICH) in GBM, anticoagulation treatment remains challenging and at times f …
Parental Age and Childhood Lymphoma and Solid Tumor Risk: A Literature Review and Meta-Analysis.
Domingues A, Moore KJ, Sample J, Kharoud H, Marcotte EL, Spector LG. Domingues A, et al. JNCI Cancer Spectr. 2022 May 2;6(3):pkac040. doi: 10.1093/jncics/pkac040. JNCI Cancer Spectr. 2022. PMID: 35639955 Free PMC article. Review.
RESULTS: A total of 15 studies covering 10 childhood solid tumor types (30 323 cases and 3 499 934 controls) were included in this analysis. A 5-year increase in maternal age was associated with an increased risk of combined central nervous system tumo …
RESULTS: A total of 15 studies covering 10 childhood solid tumor types (30 323 cases and 3 499 934 controls) were included in this analysis. …
306 results