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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1999 1
2000 1
2001 1
2002 2
2004 1
2005 2
2006 6
2007 5
2008 10
2009 13
2010 18
2011 14
2012 22
2013 35
2014 28
2015 41
2016 39
2017 49
2018 46
2019 38
2020 50
2021 48
2022 44
2023 51
2024 9

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481 results

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Page 1
Thrombotic Microangiopathy and the Kidney.
Brocklebank V, Wood KM, Kavanagh D. Brocklebank V, et al. Clin J Am Soc Nephrol. 2018 Feb 7;13(2):300-317. doi: 10.2215/CJN.00620117. Epub 2017 Oct 17. Clin J Am Soc Nephrol. 2018. PMID: 29042465 Free PMC article. Review.
How I diagnose and treat atypical hemolytic uremic syndrome.
Fakhouri F, Schwotzer N, Frémeaux-Bacchi V. Fakhouri F, et al. Blood. 2023 Mar 2;141(9):984-995. doi: 10.1182/blood.2022017860. Blood. 2023. PMID: 36322940 Free article.
Our understanding and management of atypical hemolytic uremic syndrome (aHUS) have dramatically improved in the last decade. aHUS has been established as a prototypic disease resulting from a dysregulation of the complement alternative C3 convertase. . …
Our understanding and management of atypical hemolytic uremic syndrome (aHUS) have dramatically improved in the …
Complement-driven hemolytic uremic syndrome.
Leon J, LeStang MB, Sberro-Soussan R, Servais A, Anglicheau D, Frémeaux-Bacchi V, Zuber J. Leon J, et al. Am J Hematol. 2023 May;98 Suppl 4:S44-S56. doi: 10.1002/ajh.26854. Am J Hematol. 2023. PMID: 36683290 Free article. Review.
Overactivation of the complement alternative pathway drives the pathogenesis of primary atypical hemolytic uremic syndrome (aHUS). Genetically-determined or acquired dysregulation of the complement is frequently identified in patients with aHUS, pregna …
Overactivation of the complement alternative pathway drives the pathogenesis of primary atypical hemolytic uremic sy …
Typical and Atypical Hemolytic Uremic Syndrome in the Critically Ill.
Manrique-Caballero CL, Peerapornratana S, Formeck C, Del Rio-Pertuz G, Gomez Danies H, Kellum JA. Manrique-Caballero CL, et al. Crit Care Clin. 2020 Apr;36(2):333-356. doi: 10.1016/j.ccc.2019.11.004. Epub 2020 Jan 31. Crit Care Clin. 2020. PMID: 32172817 Review.
Thrombotic microangiopathies of pregnancy: Differential diagnosis.
Gupta M, Feinberg BB, Burwick RM. Gupta M, et al. Pregnancy Hypertens. 2018 Apr;12:29-34. doi: 10.1016/j.preghy.2018.02.007. Epub 2018 Feb 16. Pregnancy Hypertens. 2018. PMID: 29674195 Review.
In pregnancy and postpartum, TMA is most commonly encountered with HELLP (hemolysis, elevated liver enzymes, low platelet count syndrome) or preeclampsia with severe features, but rarely TMA is due to thrombotic thrombocytopenic purpura (TTP) or atypical hemolytic …
In pregnancy and postpartum, TMA is most commonly encountered with HELLP (hemolysis, elevated liver enzymes, low platelet count syndrome) or …
An international consensus approach to the management of atypical hemolytic uremic syndrome in children.
Loirat C, Fakhouri F, Ariceta G, Besbas N, Bitzan M, Bjerre A, Coppo R, Emma F, Johnson S, Karpman D, Landau D, Langman CB, Lapeyraque AL, Licht C, Nester C, Pecoraro C, Riedl M, van de Kar NC, Van de Walle J, Vivarelli M, Frémeaux-Bacchi V; HUS International. Loirat C, et al. Pediatr Nephrol. 2016 Jan;31(1):15-39. doi: 10.1007/s00467-015-3076-8. Epub 2015 Apr 11. Pediatr Nephrol. 2016. PMID: 25859752 Review.
Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysregulation. ...
Atypical hemolytic uremic syndrome (aHUS) emerged during the last decade as a disease largely of complement dysr …
Complement dysregulation in glomerulonephritis.
Kaartinen K, Safa A, Kotha S, Ratti G, Meri S. Kaartinen K, et al. Semin Immunol. 2019 Oct;45:101331. doi: 10.1016/j.smim.2019.101331. Epub 2019 Nov 9. Semin Immunol. 2019. PMID: 31711769 Free article. Review.
This review describes the known mechanisms of complement dysfunction leading to different forms of primary GN (like IgA glomerulonephritis, dense deposit disease, C3 glomerulonephritis, post-infectious GN, membranous GN) and differences to atypical hemolytic urem …
This review describes the known mechanisms of complement dysfunction leading to different forms of primary GN (like IgA glomerulonephritis, …
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference.
Goodship TH, Cook HT, Fakhouri F, Fervenza FC, Frémeaux-Bacchi V, Kavanagh D, Nester CM, Noris M, Pickering MC, Rodríguez de Córdoba S, Roumenina LT, Sethi S, Smith RJ; Conference Participants. Goodship TH, et al. Kidney Int. 2017 Mar;91(3):539-551. doi: 10.1016/j.kint.2016.10.005. Epub 2016 Dec 16. Kidney Int. 2017. PMID: 27989322 Free article.
In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement plays a primary role in disease pathogenesis. ...
In both atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) complement plays a primary role in …
Eculizumab discontinuation in children and adults with atypical hemolytic-uremic syndrome: a prospective multicenter study.
Fakhouri F, Fila M, Hummel A, Ribes D, Sellier-Leclerc AL, Ville S, Pouteil-Noble C, Coindre JP, Le Quintrec M, Rondeau E, Boyer O, Provôt F, Djeddi D, Hanf W, Delmas Y, Louillet F, Lahoche A, Favre G, Châtelet V, Launay EA, Presne C, Zaloszyc A, Caillard S, Bally S, Raimbourg Q, Tricot L, Mousson C, Le Thuaut A, Loirat C, Frémeaux-Bacchi V. Fakhouri F, et al. Blood. 2021 May 6;137(18):2438-2449. doi: 10.1182/blood.2020009280. Blood. 2021. PMID: 33270832 Free article. Clinical Trial.
The optimal duration of eculizumab treatment in patients with atypical hemolytic uremic syndrome (aHUS) remains poorly defined. We conducted a prospective national multicenter open-label study to assess eculizumab discontinuation in children and adults …
The optimal duration of eculizumab treatment in patients with atypical hemolytic uremic syndrome (aHUS) remains …
Thrombocytopenia in pregnancy.
Cines DB, Levine LD. Cines DB, et al. Blood. 2017 Nov 23;130(21):2271-2277. doi: 10.1182/blood-2017-05-781971. Epub 2017 Jun 21. Blood. 2017. PMID: 28637667 Free PMC article. Review.
New criteria to diagnose preeclampsia, judicious reliance on measurement of ADAMTS13 to make management decisions in suspected thrombotic thrombocytopenic purpura, new evidence supporting the efficacy and safety of anticomplement therapy for atypical hemolytic ur …
New criteria to diagnose preeclampsia, judicious reliance on measurement of ADAMTS13 to make management decisions in suspected thrombotic th …
481 results