Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 2
2008 1
2009 1
2010 3
2011 3
2012 1
2013 3
2014 1
2015 2
2016 1
2017 1
2018 2
2019 2
2022 2
2023 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

23 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Atypical hemolytic uremic syndrome with complement gene abnormality"
Page 1
Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults.
Fremeaux-Bacchi V, Fakhouri F, Garnier A, Bienaimé F, Dragon-Durey MA, Ngo S, Moulin B, Servais A, Provot F, Rostaing L, Burtey S, Niaudet P, Deschênes G, Lebranchu Y, Zuber J, Loirat C. Fremeaux-Bacchi V, et al. Clin J Am Soc Nephrol. 2013 Apr;8(4):554-62. doi: 10.2215/CJN.04760512. Epub 2013 Jan 10. Clin J Am Soc Nephrol. 2013. PMID: 23307876 Free PMC article.
BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome (aHUS) is a rare complement-mediated kidney disease that was first recognized in children but also affects adults. ...CONCLUSION: Mortality rate was higher in children than adults wit …
BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome (aHUS) is a rare complement-mediated kidney …
Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype.
Noris M, Caprioli J, Bresin E, Mossali C, Pianetti G, Gamba S, Daina E, Fenili C, Castelletti F, Sorosina A, Piras R, Donadelli R, Maranta R, van der Meer I, Conway EM, Zipfel PF, Goodship TH, Remuzzi G. Noris M, et al. Clin J Am Soc Nephrol. 2010 Oct;5(10):1844-59. doi: 10.2215/CJN.02210310. Epub 2010 Jul 1. Clin J Am Soc Nephrol. 2010. PMID: 20595690 Free PMC article.
BACKGROUND AND OBJECTIVES: Hemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. ...Genetic complement abnormalities have been found in aHUS. DESIGN, SETTING, PARTIC …
BACKGROUND AND OBJECTIVES: Hemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia …
Atypical hemolytic uremic syndrome.
Loirat C, Frémeaux-Bacchi V. Loirat C, et al. Orphanet J Rare Dis. 2011 Sep 8;6:60. doi: 10.1186/1750-1172-6-60. Orphanet J Rare Dis. 2011. PMID: 21902819 Free PMC article. Review.
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. ...The incidence of complement-aHUS is not known precisely. However, more than 1000 aHUS patients investigated for …
Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and ren …
Genetics and CKD.
Vehaskari VM. Vehaskari VM. Adv Chronic Kidney Dis. 2011 Sep;18(5):317-23. doi: 10.1053/j.ackd.2011.07.001. Adv Chronic Kidney Dis. 2011. PMID: 21896372 Review.
Molecular biology methods have clarified the underlying mutations in several types of CKD, and in the process have revealed previously unknown genes and pathogenetic pathways. Mutations affecting the integrity of the glomerular filtration barrier cause proteinuria or nephr …
Molecular biology methods have clarified the underlying mutations in several types of CKD, and in the process have revealed previously unkno …
Complement Activation and Thrombotic Microangiopathy Associated With Monoclonal Gammopathy: A National French Case Series.
Martins M, Bridoux F, Goujon JM, Meuleman MS, Ribes D, Rondeau E, Guerry MJ, Delmas Y, Levy B, Ducloux D, Kandel-Aznar C, Le Fur A, Garrouste C, Provot F, Gibier JB, Thervet E, Bruneval P, Rabant M, Karras A, Dragon Durey MA, Fremeaux-Bacchi V, Chauvet S. Martins M, et al. Am J Kidney Dis. 2022 Sep;80(3):341-352. doi: 10.1053/j.ajkd.2021.12.014. Epub 2022 Feb 22. Am J Kidney Dis. 2022. PMID: 35217094 Free article.
RATIONALE & OBJECTIVE: Hemolytic uremic syndrome (HUS), a thrombotic microangiopathy (TMA) with kidney involvement, is a rare condition in patients with monoclonal gammopathy. ...Genetic abnormalities in complement genes known to be a …
RATIONALE & OBJECTIVE: Hemolytic uremic syndrome (HUS), a thrombotic microangiopathy (TMA) with kidney involvement, …
CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.
Piras R, Valoti E, Alberti M, Bresin E, Mele C, Breno M, Liguori L, Donadelli R, Rigoldi M, Benigni A, Remuzzi G, Noris M. Piras R, et al. Front Immunol. 2023 Jan 30;13:1011580. doi: 10.3389/fimmu.2022.1011580. eCollection 2022. Front Immunol. 2023. PMID: 36793547 Free PMC article.
INTRODUCTION: Atypical hemolytic uremic syndrome (aHUS) is a rare disease that manifests with microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure, and is associated with dysregulation of the alternative complement …
INTRODUCTION: Atypical hemolytic uremic syndrome (aHUS) is a rare disease that manifests with microangiopathic …
Genetics of hemolytic uremic syndromes.
Malina M, Roumenina LT, Seeman T, Le Quintrec M, Dragon-Durey MA, Schaefer F, Fremeaux-Bacchi V. Malina M, et al. Presse Med. 2012 Mar;41(3 Pt 2):e105-14. doi: 10.1016/j.lpm.2011.10.028. Epub 2012 Jan 20. Presse Med. 2012. PMID: 22265161 Review.
Atypical HUS appears to have a genetic basis. Mutations in genes coding for components of the alternative complement pathway are found in about 60% of cases. ...The pathophysiology of the disease and the implication of genetic abnormalities in the c …
Atypical HUS appears to have a genetic basis. Mutations in genes coding for components of the alternative complement pa …
Atypical hemolytic uremic syndrome, genetic basis, and clinical manifestations.
Kavanagh D, Goodship TH. Kavanagh D, et al. Hematology Am Soc Hematol Educ Program. 2011;2011:15-20. doi: 10.1182/asheducation-2011.1.15. Hematology Am Soc Hematol Educ Program. 2011. PMID: 22160007
Atypical hemolytic uremic syndrome (aHUS) is now well recognized to be a disease characterized by excessive complement activation in the microvasculature. ...Multiple hits are necessary for the disease to manifest, including a trigger, mutations …
Atypical hemolytic uremic syndrome (aHUS) is now well recognized to be a disease characterized by excessive c …
A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome.
Huerta A, Arjona E, Portoles J, Lopez-Sanchez P, Rabasco C, Espinosa M, Cavero T, Blasco M, Cao M, Manrique J, Cabello-Chavez V, Suñer M, Heras M, Fulladosa X, Belmar L, Sempere A, Peralta C, Castillo L, Arnau A, Praga M, Rodriguez de Cordoba S. Huerta A, et al. Kidney Int. 2018 Feb;93(2):450-459. doi: 10.1016/j.kint.2017.06.022. Epub 2017 Sep 12. Kidney Int. 2018. PMID: 28911789 Free article.
Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) refers to the thrombotic microangiopathy resulting from uncontrolled complement activation during pregnancy or the postpartum period. ...Sixteen patients presented during the first p …
Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) refers to the thrombotic microangiopathy resultin …
Severe and malignant hypertension are common in primary atypical hemolytic uremic syndrome.
Cavero T, Arjona E, Soto K, Caravaca-Fontán F, Rabasco C, Bravo L, de la Cerda F, Martín N, Blasco M, Ávila A, Huerta A, Cabello V, Jarque A, Alcázar C, Fulladosa X, Carbayo J, Anaya S, Cobelo C, Ramos N, Iglesias E, Baltar J, Martínez-Gallardo R, Pérez L, Morales E, González R, Macía M, Draibe J, Pallardó L, Quintana LF, Espinosa M, Barros X, Pereira F, Cao M, Moreno JA, Rodríguez de Córdoba S, Praga M; Spanish Group for the Study of Glomerular Diseases (GLOSEN). Cavero T, et al. Kidney Int. 2019 Oct;96(4):995-1004. doi: 10.1016/j.kint.2019.05.014. Epub 2019 May 31. Kidney Int. 2019. PMID: 31420192 Free article.
Malignant hypertension is listed among the causes of secondary thrombotic microangiopathy, but pathogenic mutations in complement genes have been reported in patients with hypertension-induced thrombotic microangiopathy. Here we investigated the frequency and severi …
Malignant hypertension is listed among the causes of secondary thrombotic microangiopathy, but pathogenic mutations in complement …
23 results