Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1991 1
1994 1
1995 1
1997 1
1998 2
1999 3
2000 1
2002 1
2004 1
2005 2
2006 3
2007 1
2008 3
2009 2
2010 1
2011 2
2012 1
2013 1
2014 4
2015 2
2017 1
2018 2
2019 1
2020 4
2021 4
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

43 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Autosomal dominant Parkinson disease 1"
Page 1
Mitochondria and Parkinson's Disease: Clinical, Molecular, and Translational Aspects.
Borsche M, Pereira SL, Klein C, Grünewald A. Borsche M, et al. J Parkinsons Dis. 2021;11(1):45-60. doi: 10.3233/JPD-201981. J Parkinsons Dis. 2021. PMID: 33074190 Free PMC article. Review.
Here, proteins encoded by the autosomal recessively inherited PD genes Parkin, PTEN-induced kinase 1 (PINK1), and DJ-1 are involved in mitochondrial pathways. Additional evidence for mitochondrial dysfunction stems from models of autosomal-dominant …
Here, proteins encoded by the autosomal recessively inherited PD genes Parkin, PTEN-induced kinase 1 (PINK1), and DJ-1 …
LRRK2 in Parkinson disease: challenges of clinical trials.
Tolosa E, Vila M, Klein C, Rascol O. Tolosa E, et al. Nat Rev Neurol. 2020 Feb;16(2):97-107. doi: 10.1038/s41582-019-0301-2. Epub 2020 Jan 24. Nat Rev Neurol. 2020. PMID: 31980808 Review.
One of the most common monogenic forms of Parkinson disease (PD) is caused by mutations in the LRRK2 gene that encodes leucine-rich repeat kinase 2 (LRRK2). LRRK2 mutations, and particularly the most common mutation Gly2019Ser, are observed in patients with autos …
One of the most common monogenic forms of Parkinson disease (PD) is caused by mutations in the LRRK2 gene that encodes leucine …
Progress in familial Parkinson's disease.
Mizuno Y, Hattori N, Yoshino H, Hatano Y, Satoh K, Tomiyama H, Li Y. Mizuno Y, et al. J Neural Transm Suppl. 2006;(70):191-204. doi: 10.1007/978-3-211-45295-0_30. J Neural Transm Suppl. 2006. PMID: 17017529 Review.
To date 11 forms of familial Parkinson's disease (PD) have been mapped to different chromosome loci, of which 6 genes have been identified as the causative genes, i.e., alpha-synuclein (SNCA), parkin, UCH-L1, PINK1, DJ-1, and LRRK2. For UCH-L1, additional fam …
To date 11 forms of familial Parkinson's disease (PD) have been mapped to different chromosome loci, of which 6 genes have bee …
Atypical presentation of dopa-responsive dystonia in Taiwan.
Weng YC, Wang CC, Wu YR. Weng YC, et al. Brain Behav. 2018 Jan 20;8(2):e00906. doi: 10.1002/brb3.906. eCollection 2018 Feb. Brain Behav. 2018. PMID: 29484265 Free PMC article. Review.
This disease has both autosomal dominant and autosomal recessive inheritance. Autosomal dominant Segawa disease is caused by GCH1 mutation on chromosome 14q22.1-q22.2. ...
This disease has both autosomal dominant and autosomal recessive inheritance. Autosomal dominant S …
Dopa-responsive dystonia--clinical and genetic heterogeneity.
Wijemanne S, Jankovic J. Wijemanne S, et al. Nat Rev Neurol. 2015 Jul;11(7):414-24. doi: 10.1038/nrneurol.2015.86. Epub 2015 Jun 23. Nat Rev Neurol. 2015. PMID: 26100751 Review.
Dopa-responsive dystonia (DRD) encompasses a group of clinically and genetically heterogeneous disorders that typically manifest as limb-onset, diurnally fluctuating dystonia and exhibit a robust and sustained response to levodopa treatment. Autosomal dominant GTP c …
Dopa-responsive dystonia (DRD) encompasses a group of clinically and genetically heterogeneous disorders that typically manifest as limb-ons …
Genetic and environmental risk factors in Parkinson's disease.
Veldman BA, Wijn AM, Knoers N, Praamstra P, Horstink MW. Veldman BA, et al. Clin Neurol Neurosurg. 1998 Mar;100(1):15-26. doi: 10.1016/s0303-8467(98)00009-2. Clin Neurol Neurosurg. 1998. PMID: 9637199 Review.
Parkinson's disease (PD) is a multifactorial disorder, caused by a combination of age, genetics and environmental factors. Nigral cells are susceptible to multiple causes of derangement of normal cell function, all of which may contribute to the same Parkinson …
Parkinson's disease (PD) is a multifactorial disorder, caused by a combination of age, genetics and environmental factors. Nig …
Advances in the genetics of Parkinson's disease.
Rosner S, Giladi N, Orr-Urtreger A. Rosner S, et al. Acta Pharmacol Sin. 2008 Jan;29(1):21-34. doi: 10.1111/j.1745-7254.2008.00731.x. Acta Pharmacol Sin. 2008. PMID: 18158863 Review.
Parkinson's disease (PD) is a neurodegenerative disorder affecting a significant proportion of the ageing population. ...Findings in the last decade suggest that the contribution of genetics to familial forms of PD is much greater than previously appreciated. Twelve …
Parkinson's disease (PD) is a neurodegenerative disorder affecting a significant proportion of the ageing population. ...Findi …
Neuroprotection and dopamine agonists.
Schapira AH. Schapira AH. Neurology. 2002 Feb 26;58(4 Suppl 1):S9-18. doi: 10.1212/wnl.58.suppl_1.s9. Neurology. 2002. PMID: 11909981 Review.
Several factors are known to be capable of inducing relatively selective dopaminergic cell death in the substantia nigra and inducing the clinical features that characterize Parkinson's disease (PD). Neuronal toxins such as 1-methyl-4-phenyl-1,2 …
Several factors are known to be capable of inducing relatively selective dopaminergic cell death in the substantia nigra and inducing the …
Glial reactions in Parkinson's disease.
McGeer PL, McGeer EG. McGeer PL, et al. Mov Disord. 2008 Mar 15;23(4):474-83. doi: 10.1002/mds.21751. Mov Disord. 2008. PMID: 18044695 Review.
Dopaminergic neurons of the substantia nigra are particularly vulnerable to oxidative and inflammatory attack. Such processes may play a crucial role in the etiology of Parkinson disease (PD). Since glia are the main generators of these processes, the possibility th …
Dopaminergic neurons of the substantia nigra are particularly vulnerable to oxidative and inflammatory attack. Such processes may play a cru …
Molecular genetics of dopa-responsive dystonia.
Ichinose H, Suzuki T, Inagaki H, Ohye T, Nagatsu T. Ichinose H, et al. Biol Chem. 1999 Dec;380(12):1355-64. doi: 10.1515/BC.1999.175. Biol Chem. 1999. PMID: 10661862 Review.
The causative genes of two types of hereditary dopa-responsive dystonia (DRD) due to dopamine (DA) deficiency in the nigrostriatum DA neurons have been elucidated. Autosomal dominant DRD (AD-DRD) was originally described by Segawa as hereditary progressive dystonia …
The causative genes of two types of hereditary dopa-responsive dystonia (DRD) due to dopamine (DA) deficiency in the nigrostriatum DA neuron …
43 results