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How I approach B-lymphoblastic lymphoma in children.
Devine KJ, Fries C, Hermiston M, Wistinghausen B. Devine KJ, et al. Pediatr Blood Cancer. 2023 Aug;70(8):e30401. doi: 10.1002/pbc.30401. Epub 2023 May 9. Pediatr Blood Cancer. 2023. PMID: 37158503
Outcomes are favorable following treatment modeled after acute lymphoblastic leukemia (ALL) regimens, but prognosis is dismal after relapse, and there are no established features for predicting therapy response. Ongoing US and international trials will include the largest …
Outcomes are favorable following treatment modeled after acute lymphoblastic leukemia (ALL) regimens, but prognosis is dismal after relapse, …
Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues.
Meyer JA, Zhou D, Mason CC, Downie JM, Rodic V, Abromowitch M, Wistinghausen B, Termuhlen AM, Angiolillo AL, Perkins SL, Lones MA, Barnette P, Schiffman JD, Miles RR. Meyer JA, et al. Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26363. Epub 2016 Dec 13. Pediatr Blood Cancer. 2017. PMID: 27957801
BACKGROUND: Recurrent genomic changes in B-lymphoblastic leukemia (B-ALL) identified by genome-wide single-nucleotide polymorphism (SNP) microarray analysis provide important prognostic information, but gene copy number analysis of its rare lymphoma counterpart, B-lymph …
BACKGROUND: Recurrent genomic changes in B-lymphoblastic leukemia (B-ALL) identified by genome-wide single-nucleotide polymorphism (SNP) mic …
B-Lymphoblastic Lymphoma in Children: A Case Series From a Single Institution.
Devine KJ, Trivedi H, Reilly AF. Devine KJ, et al. J Pediatr Hematol Oncol. 2024 Apr 1;46(3):e254-e258. doi: 10.1097/MPH.0000000000002828. Epub 2024 Feb 16. J Pediatr Hematol Oncol. 2024. PMID: 38408123 Free PMC article.
BACKGROUND: Pediatric B-lymphoblastic lymphoma is an uncommon subtype of non-Hodgkin lymphoma. ...CONCLUSIONS: The prognostic significance of cytogenetic changes in B-lymphoblastic lymphoma is not well described but may offer improved ris …
BACKGROUND: Pediatric B-lymphoblastic lymphoma is an uncommon subtype of non-Hodgkin lymphoma. ...CONCLUSIONS: The prog …
Predicting transformation in follicular lymphoma.
de Jong D, de Boer JP. de Jong D, et al. Leuk Lymphoma. 2009 Sep;50(9):1406-11. doi: 10.1080/10428190903093815. Leuk Lymphoma. 2009. PMID: 19606378 Review.
Mostly, the transformed phase has a morphology of diffuse large B-cell lymphoma, and more rarely the features reminiscent of Burkitt lymphoma or precursor B-lymphoblastic lymphoma are seen. The risk of transformation may be determined by factors that influenc …
Mostly, the transformed phase has a morphology of diffuse large B-cell lymphoma, and more rarely the features reminiscent of Burkitt lymphom …
Analysis of clinicopathological and cytogenetic differences between B-lymphoblastic lymphoma and B-lymphoblastic leukemia in childhood.
Knez V, Bao L, Carstens B, Liang X. Knez V, et al. Leuk Lymphoma. 2020 Sep;61(9):2129-2135. doi: 10.1080/10428194.2020.1761970. Epub 2020 May 19. Leuk Lymphoma. 2020. PMID: 32427530
Performing a retrospective review of 126 cases of B-ALL and 18 cases of B-LBL in patients 18 years, revealed the following significant differences: younger age of presentation for leukemia; increased cytogenetic abnormalities in leukemia than lymphoma, specifically increased recu …
Performing a retrospective review of 126 cases of B-ALL and 18 cases of B-LBL in patients 18 years, revealed the following significant diffe …
Primary cutaneous B-cell lymphoma: A single-center 5-year experience.
Jacob LA, Asati V, Lakshmaiah KC, Govind BK, Lokanatha D, Babu SM, Lokesh KN, Rudresh AH, Rajeev LK, Mulchandani NJ, Anand A, Koppaka D, Mysore SN. Jacob LA, et al. Indian J Cancer. 2018 Apr-Jun;55(2):134-137. doi: 10.4103/ijc.IJC_418_17. Indian J Cancer. 2018. PMID: 30604723 Free article.
Two patients had primary cutaneous follicle center lymphoma, whereas the remaining 1 patient had precursor B-lymphoblastic lymphoma. All 5 DLBCL cases were treated with CHOP chemotherapy, and rituximab was given to 3 patients. Of the primary cutaneous follicl …
Two patients had primary cutaneous follicle center lymphoma, whereas the remaining 1 patient had precursor B-lymphoblastic …
Precursor B lymphoblastic lymphoma presenting as lytic bone lesions.
Iravani S, Singleton TP, Ross CW, Schnitzer B. Iravani S, et al. Am J Clin Pathol. 1999 Dec;112(6):836-43. doi: 10.1093/ajcp/112.6.836. Am J Clin Pathol. 1999. PMID: 10587707
Precursor B lymphoblastic lymphoma is an aggressive but potentially curable disease. ...Immunophenotyping these neoplasms is essential to establish the correct diagnosis of precursor B lymphoblastic lymphoma, and a panel of antibodies is …
Precursor B lymphoblastic lymphoma is an aggressive but potentially curable disease. ...Immunophenotyping these neoplas …
Clinical features and treatment outcomes of adult B- and T-lymphoblastic lymphoma: results of multicentre analysis in Korea.
Chang MH, Kim SJ, Kim K, Oh SY, Lee DH, Huh J, Ko YH, Choi CW, Yang DH, Won JH, Kim WS, Suh C. Chang MH, et al. Leuk Lymphoma. 2009 Jul;50(7):1119-25. doi: 10.1080/10428190902926999. Leuk Lymphoma. 2009. PMID: 19557632
We performed a retrospective multicentre analysis to study the clinical features and treatment outcomes of B-lymphoblastic lymphoma (B-LBL) and T-lymphoblastic lymphoma (T-LBL) in Asian adult patients, and identify risk factors that predict relapse and …
We performed a retrospective multicentre analysis to study the clinical features and treatment outcomes of B-lymphoblastic …
Functional characterization of two rare BCR-FGFR1+ leukemias.
Barnes EJ, Leonard J, Medeiros BC, Druker BJ, Tognon CE. Barnes EJ, et al. Cold Spring Harb Mol Case Stud. 2020 Apr 1;6(2):a004838. doi: 10.1101/mcs.a004838. Print 2020 Apr. Cold Spring Harb Mol Case Stud. 2020. PMID: 31980503 Free PMC article.
The syndrome is a myeloproliferative neoplasm characterized by eosinophilia and lymphadenopathy, with risk of progression to either acute myeloid leukemia (AML) or T- or B-lymphoblastic lymphoma/leukemia. Within the EMS subtype, translocations between breakpo …
The syndrome is a myeloproliferative neoplasm characterized by eosinophilia and lymphadenopathy, with risk of progression to either acute my …
B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements are aggressive neoplasms with clinical and pathologic features distinct from Burkitt lymphoma and diffuse large B-cell lymphoma.
Snuderl M, Kolman OK, Chen YB, Hsu JJ, Ackerman AM, Dal Cin P, Ferry JA, Harris NL, Hasserjian RP, Zukerberg LR, Abramson JS, Hochberg EP, Lee H, Lee AI, Toomey CE, Sohani AR. Snuderl M, et al. Am J Surg Pathol. 2010 Mar;34(3):327-40. doi: 10.1097/PAS.0b013e3181cd3aeb. Am J Surg Pathol. 2010. PMID: 20118770 Free PMC article.
B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements, also known as "double-hit" lymphomas (DHL), are rare neoplasms characterized by highly aggressive clinical behavior, complex karyotypes, and a spectrum of pathologic features overlapping with Burkitt lymphoma (BL), …
B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements, also known as "double-hit" lymphomas (DHL), are rare neoplasms characteriz …
14 results