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Seven chronic granulomatous disease cases in a single-center experience and a review of the literature.
Kutluğ Ş, Şensoy G, Birinci A, Saraymen B, Yavuz Köker M, Yιldιran A. Kutluğ Ş, et al. Asian Pac J Allergy Immunol. 2018 Mar;36(1):35-41. doi: 10.12932/AP0859. Asian Pac J Allergy Immunol. 2018. PMID: 28577521 Free article. Review.
Severe invasive infections due to Aspergillus, Staphylococcus, and Serratia species were reported. Frequent lung and lymph node involvement was observed during follow-up of the cases. CONCLUSIONS: CGD is life-threatening disease that involves deep-seated infection. ...
Severe invasive infections due to Aspergillus, Staphylococcus, and Serratia species were reported. Frequent lung and lymph node involvement …
BCG infection (BCGitis) following intravesical instillation for bladder cancer and time interval between treatment and presentation: A systematic review.
Cabas P, Rizzo M, Giuffrè M, Antonello RM, Trombetta C, Luzzati R, Liguori G, Di Bella S. Cabas P, et al. Urol Oncol. 2021 Feb;39(2):85-92. doi: 10.1016/j.urolonc.2020.11.037. Epub 2020 Dec 8. Urol Oncol. 2021. PMID: 33308969
The analysis detected a cluster between lungs, liver, and bone marrow complications on one side and muscular and osteoarticular or vascular complications on the other side was also observed. CONCLUSIONS: BCG infection after intravesical BCG for bladder cancer may develop e …
The analysis detected a cluster between lungs, liver, and bone marrow complications on one side and muscular and osteoarticular or vascular …
Expanding the clinical and genetic spectrum of G6PD deficiency: The occurrence of BCGitis and novel missense mutation.
Khan TA, Mazhar H, Nawaz M, Kalsoom K, Ishfaq M, Asif H, Rahman H, Qasim M, Naz F, Hussain M, Khattak B, Ullah W, Cabral-Marques O, Butt J, Iqbal A. Khan TA, et al. Microb Pathog. 2017 Jan;102:160-165. doi: 10.1016/j.micpath.2016.11.025. Epub 2016 Nov 30. Microb Pathog. 2017. PMID: 27914961
Genetic and in silico analyses were carried out by Sanger sequencing and mutation pathogenicity predicted using bioinformatics tools, respectively. Activated neutrophils and monocytes from patients displayed impaired oxidative burst. ...
Genetic and in silico analyses were carried out by Sanger sequencing and mutation pathogenicity predicted using bioinformatics tools, …
Novel mutatıons and diverse clinical phenotypes in recombinase-activating gene 1 deficiency.
Kutukculer N, Gulez N, Karaca NE, Aksu G, Berdeli A. Kutukculer N, et al. Ital J Pediatr. 2012 Mar 16;38:8. doi: 10.1186/1824-7288-38-8. Ital J Pediatr. 2012. PMID: 22424479 Free PMC article.
Genotype-phenotype correlation was not significantly apparent in most of the cases. BCG infection was observed in 36.4% of patients (two BCG-osis and two BCG-itis). CONCLUSION: Epigenetic factors such as compound genetic defects, enviromental factors, and exposure to recur …
Genotype-phenotype correlation was not significantly apparent in most of the cases. BCG infection was observed in 36.4% of patients ( …
Clinical, genetic and immunological characteristics of 40 Chinese patients with CD40 ligand deficiency.
Du X, Tang W, Chen X, Zeng T, Wang Y, Chen Z, Xu T, Zhou L, Tang X, An Y, Zhao X. Du X, et al. Scand J Immunol. 2019 Oct;90(4):e12798. doi: 10.1111/sji.12798. Epub 2019 Jul 21. Scand J Immunol. 2019. PMID: 31179555 Free article.
It was intriguing that reduced IgM levels were observed in 12.5% of patients, while normal or elevated IgA levels were shown in 47.5% of patients. Thirty-seven unique mutations were identified in 40 patients; of these, 10 were novel. Furthermore, we observed a lower …
It was intriguing that reduced IgM levels were observed in 12.5% of patients, while normal or elevated IgA levels were shown in 47.5% …
Clinical, laboratory and imaging findings of the patients with disseminated bacilli Calmette-Guerin disease.
Sharifi Asadi P, Aghamohammadi A, Mahmoudi S, Pourakbari B, Saboui F, Mamishi S. Sharifi Asadi P, et al. Allergol Immunopathol (Madr). 2015 May-Jun;43(3):254-8. doi: 10.1016/j.aller.2014.01.003. Epub 2014 Jun 16. Allergol Immunopathol (Madr). 2015. PMID: 24948188
CONCLUSION: These findings confirm the need to do sonography as well as bone imaging immediately in all patients with BCGitis. Assessment of the inflammatory factors in order to predict the prognosis of the disease is recommended. Furthermore, complete blood count w …
CONCLUSION: These findings confirm the need to do sonography as well as bone imaging immediately in all patients with BCGitis. Assess …
Bacillus Calmette-Guerin (BCG) Vaccine-associated Complications in Immunodeficient Patients Following Stem Cell Transplantation.
NaserEddin A, Dinur-Schejter Y, Shadur B, Zaidman I, Even-Or E, Averbuch D, Shamriz O, Tal Y, Shaag A, Warnatz K, Elpeleg O, Stepensky P. NaserEddin A, et al. J Clin Immunol. 2021 Jan;41(1):147-162. doi: 10.1007/s10875-020-00892-6. Epub 2020 Oct 27. J Clin Immunol. 2021. PMID: 33111199 Free PMC article.
The most significant risk factor for developing BCG-related complications was T cell deficiency (47.6% of the non-complicated vs 83.3% of the BCGitis and 100% of the BCGosis groups had T cell lymphopenia, p = 0.013). ...Among T cell-deficient patients, lower NK (127 vs 698 …
The most significant risk factor for developing BCG-related complications was T cell deficiency (47.6% of the non-complicated vs 83.3% of th …
Systemic bacillus Calmette-Guerin infection, 'BCGitis', in patients treated by intravesical bacillus Calmette-Guerin therapy for bladder cancer.
Steg A, Leleu C, Debré B, Boccon-Gibod L, Sicard D. Steg A, et al. Eur Urol. 1989;16(3):161-4. doi: 10.1159/000471561. Eur Urol. 1989. PMID: 2744050
Among 169 patients treated for supeficial bladder tumor with 150 mg Pasteur-strain bacillus Calmette-Guerin (BCG) intravesical instillation, 5 cases of 'BCGitis' were observed, i.e. a severe systemic BCG infection with bronchopulmonary lesions and granulomatous hepa …
Among 169 patients treated for supeficial bladder tumor with 150 mg Pasteur-strain bacillus Calmette-Guerin (BCG) intravesical instillation, …
Adjuvant intravesical treatment for nonmuscle invasive bladder cancer: The importance of the strain and maintenance.
Guerrero-Ramos F, Lara-Isla A, Justo-Quintas J, Duarte-Ojeda JM, de la Rosa-Kehrmann F, Villacampa-Aubá F. Guerrero-Ramos F, et al. Actas Urol Esp. 2017 Nov;41(9):590-595. doi: 10.1016/j.acuro.2017.03.003. Epub 2017 Apr 28. Actas Urol Esp. 2017. PMID: 28457495 English, Spanish.
We calculated the relapse-free survival rate in each group and compared the patients who completed the maintenance treatments against those who did not. To identify the predictors of relapse, we performed a multivariate analysis. We also assessed the toxicity by analysing …
We calculated the relapse-free survival rate in each group and compared the patients who completed the maintenance treatments against those …
Clinical features and genetic analysis of 20 Chinese patients with X-linked hyper-IgM syndrome.
Wang LL, Zhou W, Zhao W, Tian ZQ, Wang WF, Wang XF, Chen TX. Wang LL, et al. J Immunol Res. 2014;2014:683160. doi: 10.1155/2014/683160. Epub 2014 Aug 20. J Immunol Res. 2014. PMID: 25215306 Free PMC article.
The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients, 65%), and protracted diarrhea (13 patients, 65%). Six patients had BCGitis. Six patients received hematopoietic stem cell transplan …
The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients …
14 results