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2003 3
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67 results

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Page 1
Smoking Is Associated With Basal Cell Hyperplasia on Prostate Biopsy Specimens.
Freitas DM, Andriole GL, Freedland SJ, Neto BS, Moreira DM. Freitas DM, et al. Am J Clin Pathol. 2021 Oct 13;156(5):934-938. doi: 10.1093/ajcp/aqab030. Am J Clin Pathol. 2021. PMID: 33939794
Therefore, we sought to evaluate whether smoking status is associated with the presence of basal cell hyperplasia (BCH). METHODS: We performed a retrospective analysis of 8,196 men aged 50 to 75 years with prostate-specific antigen values between 2.5 g/mL and …
Therefore, we sought to evaluate whether smoking status is associated with the presence of basal cell hyperplasia (BCH) …
CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis.
Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, Shimonosono M, Shimonosono R, Maekawa H, Dolinsky L, Wilkins B, Klein J, Wei J, Nunes K, Lynch K, Spergel JM, Hamilton KE, Ruffner MA, Karakasheva TA, Whelan KA, Nakagawa H, Muir AB. Hara T, et al. Cell Mol Gastroenterol Hepatol. 2022;13(5):1449-1467. doi: 10.1016/j.jcmgh.2022.01.018. Epub 2022 Jan 30. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35108658 Free PMC article.
BACKGROUND & AIMS: Although basal cell hyperplasia is a histologic hallmark of eosinophilic esophagitis (EoE), little is known about the capabilities of epithelial renewal and differentiation in the EoE inflammatory milieu. ...IL4 and IL13 stimulation dep …
BACKGROUND & AIMS: Although basal cell hyperplasia is a histologic hallmark of eosinophilic esophagitis (EoE), litt …
Allergen-induced NLRP3/caspase1/IL-18 signaling initiate eosinophilic esophagitis and respective inhibitors protect disease pathogenesis.
Yadavalli CS, Upparahalli Venkateshaiah S, Kumar S, Kandikattu HK, Oruganti L, Kathera CS, Mishra A. Yadavalli CS, et al. Commun Biol. 2023 Jul 31;6(1):763. doi: 10.1038/s42003-023-05130-4. Commun Biol. 2023. PMID: 37524769 Free PMC article.
Most importantly, we present that intravascular rIL-18 delivery to deltadblGATA mice and CD2-IL-5 mice show the development of EoE characteristics feature like degranulated and intraepithelial eosinophils, basal cell hyperplasia, remodeling and fibrosis. Simi …
Most importantly, we present that intravascular rIL-18 delivery to deltadblGATA mice and CD2-IL-5 mice show the development of EoE character …
Baseline Basal Cell Hyperplasia Is not Associated With Baseline Lower Urinary Tract Symptoms, Baseline Clinical Prostatitis or Prostate Cancer in Repeat Biopsies.
Freitas D, Andriole GL, Freedland SJ, Neto BS, Moreira DM. Freitas D, et al. Urology. 2019 Jul;129:160-164. doi: 10.1016/j.urology.2019.02.034. Epub 2019 Mar 23. Urology. 2019. PMID: 30914334 Clinical Trial.
OBJECTIVES: To evaluate whether the presence of basal cell hyperplasia (BCH) in negative biopsies is associated with concurrent lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH), clinical prostatitis, and future prostate cancer …
OBJECTIVES: To evaluate whether the presence of basal cell hyperplasia (BCH) in negative biopsies is associated with co …
Effect of Proton Pump Inhibitor Treatment in "PPI Non-responsive" Patients with Eosinophilic Esophagitis.
Thakkar KP, Philpott H, Lafata S, Fowler M, Keene S, Iuga A, Dellon E. Thakkar KP, et al. J Gastrointestin Liver Dis. 2023 Mar 31;32(1):15-22. doi: 10.15403/jgld-4746. J Gastrointestin Liver Dis. 2023. PMID: 37004219 Free PMC article.
When comparing the 50% and <50% decrease groups, differences in endoscopic features were identified, but the 50% group had improvement in eosinophil degranulation, microabscesses, spongiosis, and basal cell hyperplasia. CONCLUSION: Peak eosinophil counts d …
When comparing the 50% and <50% decrease groups, differences in endoscopic features were identified, but the 50% group had improvement in …
Anemoside B4 prevents chronic obstructive pulmonary disease through alleviating cigarette smoke-induced inflammatory response and airway epithelial hyperplasia.
Ma H, Zhou Z, Chen L, Wang L, Muge Q. Ma H, et al. Phytomedicine. 2022 Dec;107:154431. doi: 10.1016/j.phymed.2022.154431. Epub 2022 Sep 2. Phytomedicine. 2022. PMID: 36115169
However, in recent years, there is no relevant literature report on the therapeutic effect of B4 on COPD, and the anti-inflammatory and inhibitory effects of anemoside B4 on basal cell hyperplasia in CS-induced COPD have not been clearly established. ...Bronc …
However, in recent years, there is no relevant literature report on the therapeutic effect of B4 on COPD, and the anti-inflammatory and inhi …
Plasminogen Activator Inhibitor-1 as a Marker of Esophageal Functional Changes in Pediatric Eosinophilic Esophagitis.
Williamson P, Proudfoot J, Gharibans A, Dohil L, Newbury R, Barsamian J, Hassan M, Rawson R, Katzka D, Kurten R, Dohil R, Mousa H, Aceves S. Williamson P, et al. Clin Gastroenterol Hepatol. 2022 Jan;20(1):57-64.e3. doi: 10.1016/j.cgh.2020.09.040. Epub 2020 Sep 30. Clin Gastroenterol Hepatol. 2022. PMID: 33007513 Free PMC article.
METHODS: Esophageal biopsy specimens from children with and without EoE and primary human esophageal epithelial cells were used for PAI-1 immunohistochemistry, and cell proliferation experiments. PAI-1 immunostaining and basal cell hyperplasia were assessed i …
METHODS: Esophageal biopsy specimens from children with and without EoE and primary human esophageal epithelial cells were used for PAI-1 im …
Epidermal growth factor receptor family in lung cancer and premalignancy.
Franklin WA, Veve R, Hirsch FR, Helfrich BA, Bunn PA Jr. Franklin WA, et al. Semin Oncol. 2002 Feb;29(1 Suppl 4):3-14. doi: 10.1053/sonc.2002.31520. Semin Oncol. 2002. PMID: 11894009 Review.
Overexpression of EGFR is one of the earliest and most consistent abnormalities in bronchial epithelium of high-risk smokers. It is present at the stage of basal cell hyperplasia and persists through squamous metaplasia, dysplasia, and carcinoma in situ. ...
Overexpression of EGFR is one of the earliest and most consistent abnormalities in bronchial epithelium of high-risk smokers. It is present …
High-intensity focused ultrasound for the treatment of prostate cancer: assessing location of failure after focal therapy in prostate cancer and review of histological characteristics and clinicopathologic correlates after treatment-a 5-year experience.
Collins K, Brocken E, Bahler CD, Alabd A, Koch MO, Cheng L. Collins K, et al. Hum Pathol. 2022 Jan;119:79-84. doi: 10.1016/j.humpath.2021.11.005. Epub 2021 Nov 18. Hum Pathol. 2022. PMID: 34801600
Inclusion criteria included pathologically confirmed prostate cancer and clinical stage T1/T2 disease. We describe the histological changes in post-treatment needle biopsies as part of routine follow-up. ...Histological examination of benign glands revealed glandular heter …
Inclusion criteria included pathologically confirmed prostate cancer and clinical stage T1/T2 disease. We describe the histological c …
Prostate Cancer in Male-to-Female Transgender Individuals: Histopathologic Findings and Association With Gender-affirming Hormonal Therapy.
Baraban E, Ding CC, White M, Vohra P, Simko J, Boyle K, Guo C, Zhang M, Dobs A, Ketheeswaran S, Liang F, Epstein JI. Baraban E, et al. Am J Surg Pathol. 2022 Dec 1;46(12):1650-1658. doi: 10.1097/PAS.0000000000001964. Epub 2022 Aug 26. Am J Surg Pathol. 2022. PMID: 36006769
Both of these specimens showed diffuse glandular atrophy and basal cell hyperplasia, indicative of hormone therapy effect on benign prostatic tissue. ...Hormone therapy administered for gender identity affirmation induces histopathologic changes to both benig …
Both of these specimens showed diffuse glandular atrophy and basal cell hyperplasia, indicative of hormone therapy effe …
67 results