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Quoted phrase not found in phrase index: "Basal cell carcinoma, susceptibility to, 7"
Page 1
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma.
Bonilla X, Parmentier L, King B, Bezrukov F, Kaya G, Zoete V, Seplyarskiy VB, Sharpe HJ, McKee T, Letourneau A, Ribaux PG, Popadin K, Basset-Seguin N, Ben Chaabene R, Santoni FA, Andrianova MA, Guipponi M, Garieri M, Verdan C, Grosdemange K, Sumara O, Eilers M, Aifantis I, Michielin O, de Sauvage FJ, Antonarakis SE, Nikolaev SI. Bonilla X, et al. Nat Genet. 2016 Apr;48(4):398-406. doi: 10.1038/ng.3525. Epub 2016 Mar 7. Nat Genet. 2016. PMID: 26950094
Basal cell carcinoma (BCC) of the skin is the most common malignant neoplasm in humans. ...However, 85% of the BCCs also harbored additional driver mutations in other cancer-related genes. We observed recurrent mutations in MYCN (30%), PPP6C (15%), STK
Basal cell carcinoma (BCC) of the skin is the most common malignant neoplasm in humans. ...However, 85% of the BCCs als
Nervous system (NS) Tumors in Cancer Predisposition Syndromes.
Patil P, Pencheva BB, Patil VM, Fangusaro J. Patil P, et al. Neurotherapeutics. 2022 Oct;19(6):1752-1771. doi: 10.1007/s13311-022-01277-w. Epub 2022 Sep 2. Neurotherapeutics. 2022. PMID: 36056180 Free PMC article. Review.
Genetic counseling, defined as "the process of helping people understand and adapt to the medical, psychological and familial implications of genetic contributions to disease" plays a vital role in the adaptation to a genetic diagnosis and the overall management of these d …
Genetic counseling, defined as "the process of helping people understand and adapt to the medical, psychological and familial implications o …
Basal cell carcinoma genetic susceptibility increases the rate of skin ageing: a Mendelian randomization study.
van der Poort EKJ, Gunn DA, Beekman M, Griffiths CEM, Slagboom PE, van Heemst D, Noordam R. van der Poort EKJ, et al. J Eur Acad Dermatol Venereol. 2020 Jan;34(1):97-100. doi: 10.1111/jdv.15880. Epub 2019 Sep 5. J Eur Acad Dermatol Venereol. 2020. PMID: 31419349
BACKGROUND: Onset of basal cell carcinoma (BCC) is connected to skin ageing, but it is unclear whether higher BCC genetic susceptibility drives skin ageing. ...RESULTS: A higher BCC genetic risk score was associated with a higher perceived age ( …
BACKGROUND: Onset of basal cell carcinoma (BCC) is connected to skin ageing, but it is unclear whether higher BCC genet …
Genome-wide association studies and polygenic risk scores for skin cancer: clinically useful yet?
Roberts MR, Asgari MM, Toland AE. Roberts MR, et al. Br J Dermatol. 2019 Dec;181(6):1146-1155. doi: 10.1111/bjd.17917. Epub 2019 Jul 7. Br J Dermatol. 2019. PMID: 30908599 Free PMC article. Review.
OBJECTIVES: To review published GWAS and PRS studies for melanoma, cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC), and discuss their potential clinical utility. ...Clinical translation will require well-powered validatio …
OBJECTIVES: To review published GWAS and PRS studies for melanoma, cutaneous squamous cell carcinoma (cSCC) and basal
Polygenic Risk Scores Allow Risk Stratification for Keratinocyte Cancer in Organ-Transplant Recipients.
Seviiri M, Law MH, Ong JS, Gharahkhani P, Nyholt DR, Olsen CM, Whiteman DC, MacGregor S. Seviiri M, et al. J Invest Dermatol. 2021 Feb;141(2):325-333.e6. doi: 10.1016/j.jid.2020.06.017. Epub 2020 Jun 29. J Invest Dermatol. 2021. PMID: 32615124 Free article.
Organ-transplant recipients have an elevated risk of keratinocyte cancers: basal cell carcinoma (BCC) and squamous cell carcinoma. We assessed whether polygenic risk scores (PRSs) generated in nontransplantees from the UK Biobank and 23an …
Organ-transplant recipients have an elevated risk of keratinocyte cancers: basal cell carcinoma (BCC) and squamous c
DNA repair and susceptibility to basal cell carcinoma: a case-control study.
Wei Q, Matanoski GM, Farmer ER, Hedayati MA, Grossman L. Wei Q, et al. Am J Epidemiol. 1994 Oct 1;140(7):598-607. doi: 10.1093/oxfordjournals.aje.a117297. Am J Epidemiol. 1994. PMID: 7942760
This study investigated the role of DNA repair in susceptibility to sunlight-induced basal cell carcinoma using a host cell reactivation assay in peripheral lymphocytes. The study included Maryland basal cell carcinoma patie …
This study investigated the role of DNA repair in susceptibility to sunlight-induced basal cell carcinoma using …
Reviewing the genetic alterations in high-risk cutaneous squamous cell carcinoma: A search for prognostic markers and therapeutic targets.
Ashford BG, Clark J, Gupta R, Iyer NG, Yu B, Ranson M. Ashford BG, et al. Head Neck. 2017 Jul;39(7):1462-1469. doi: 10.1002/hed.24765. Epub 2017 Apr 3. Head Neck. 2017. PMID: 28370784 Review.
Cutaneous squamous cell carcinoma (SCC) is second only in incidence to basal cell carcinoma (BCC), effecting up to 500 000 people in the United States annually. ...Currently, there are no clinically useful biomarkers of metastatic potential in p …
Cutaneous squamous cell carcinoma (SCC) is second only in incidence to basal cell carcinoma (BCC), effect …
Amyloid β oligomers inhibit growth of human cancer cells.
Pavliukeviciene B, Zentelyte A, Jankunec M, Valiuliene G, Talaikis M, Navakauskiene R, Niaura G, Valincius G. Pavliukeviciene B, et al. PLoS One. 2019 Sep 11;14(9):e0221563. doi: 10.1371/journal.pone.0221563. eCollection 2019. PLoS One. 2019. PMID: 31509551 Free PMC article.
Effects of amyloid beta (Abeta) oligomers on viability and function of cell lines such as NB4 (human acute promyelocytic leukemia), A549 (human lung cancer (adenocarcinomic alveolar basal epithelial tumor)) and MCF-7 (human breast cancer (invasive breast duct …
Effects of amyloid beta (Abeta) oligomers on viability and function of cell lines such as NB4 (human acute promyelocytic leukemia), A …
Pan-TRK Immunohistochemistry Is Highly Correlated With NTRK3 Gene Rearrangements in Salivary Gland Tumors.
Csanyi-Bastien M, Lanic MD, Beaussire L, Ferric S, François A, Meseure D, Jardin F, Wassef M, Ruminy P, Laé M. Csanyi-Bastien M, et al. Am J Surg Pathol. 2021 Nov 1;45(11):1487-1498. doi: 10.1097/PAS.0000000000001718. Am J Surg Pathol. 2021. PMID: 33899788
Secretory carcinoma (SC) is characterized by ETV6 rearrangements, most often ETV6-NTRK3 fusion. ...When any pan-TRK staining (nuclear or cytoplasmic with any staining intensity) was considered to indicate positivity, 22 of 23 SCs with ETV6-NTRK3 fusion (95.7%) and 3 …
Secretory carcinoma (SC) is characterized by ETV6 rearrangements, most often ETV6-NTRK3 fusion. ...When any pan-TRK staining (nuclear …
Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans.
Abel EL, Angel JM, Riggs PK, Langfield L, Lo HH, Person MD, Awasthi YC, Wang LE, Strom SS, Wei Q, DiGiovanni J. Abel EL, et al. J Natl Cancer Inst. 2010 Nov 3;102(21):1663-75. doi: 10.1093/jnci/djq392. Epub 2010 Oct 21. J Natl Cancer Inst. 2010. PMID: 20966433 Free PMC article.
Having identified glutathione S-transferase alpha4 (Gsta4) as a candidate tumor promotion susceptibility gene that mapped within the delimited region, we analyzed Gsta4-deficient mice (n = 62) for susceptibility to skin tumor promotion by TPA. ...In addition, a four …
Having identified glutathione S-transferase alpha4 (Gsta4) as a candidate tumor promotion susceptibility gene that mapped within the …
37 results