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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 1
2000 1
2009 2
2010 2
2011 1
2012 3
2013 2
2015 2
2016 3
2017 2
2018 1
2020 1
2022 1
2024 0

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18 results

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Page 1
Cuticular Drusen: Clinical Phenotypes and Natural History Defined Using Multimodal Imaging.
Balaratnasingam C, Cherepanoff S, Dolz-Marco R, Killingsworth M, Chen FK, Mendis R, Mrejen S, Too LK, Gal-Or O, Curcio CA, Freund KB, Yannuzzi LA. Balaratnasingam C, et al. Ophthalmology. 2018 Jan;125(1):100-118. doi: 10.1016/j.ophtha.2017.08.033. Epub 2017 Sep 28. Ophthalmology. 2018. PMID: 28964580
PURPOSE: To define the range and life cycles of cuticular drusen phenotypes using multimodal imaging and to review the histologic characteristics of cuticular drusen. DESIGN: Retrospective, observational cohort study and experimental laboratory study. PARTICIPANTS: Two hun …
PURPOSE: To define the range and life cycles of cuticular drusen phenotypes using multimodal imaging and to review the histologic characteri …
Aging is not a disease: distinguishing age-related macular degeneration from aging.
Ardeljan D, Chan CC. Ardeljan D, et al. Prog Retin Eye Res. 2013 Nov;37:68-89. doi: 10.1016/j.preteyeres.2013.07.003. Epub 2013 Aug 9. Prog Retin Eye Res. 2013. PMID: 23933169 Free PMC article. Review.
In AMD, imbalances in the M1 and M2 populations together with activation of retinal microglia are observed and potentially contribute to tissue degeneration. Nonetheless, the retina persists in a state of chronic inflammation and increased expression of certain cytokines a …
In AMD, imbalances in the M1 and M2 populations together with activation of retinal microglia are observed and potentially contribute …
Cuticular Drusen in Age-Related Macular Degeneration: Association with Progression and Impact on Visual Sensitivity.
Goh KL, Chen FK, Balaratnasingam C, Abbott CJ, Hodgson LAB, Guymer RH, Wu Z. Goh KL, et al. Ophthalmology. 2022 Jun;129(6):653-660. doi: 10.1016/j.ophtha.2022.01.028. Epub 2022 Feb 1. Ophthalmology. 2022. PMID: 35120992
PURPOSE: To determine the prognostic significance and impact on visual function of the cuticular drusen phenotype in a cohort with intermediate age-related macular degeneration (AMD). DESIGN: Longitudinal, observational study. PARTICIPANTS: Participants aged 50 years or ol …
PURPOSE: To determine the prognostic significance and impact on visual function of the cuticular drusen phenotype in a cohort with intermedi …
The spectrum of phenotypes caused by variants in the CFH gene.
Boon CJ, van de Kar NC, Klevering BJ, Keunen JE, Cremers FP, Klaver CC, Hoyng CB, Daha MR, den Hollander AI. Boon CJ, et al. Mol Immunol. 2009 May;46(8-9):1573-94. doi: 10.1016/j.molimm.2009.02.013. Epub 2009 Mar 17. Mol Immunol. 2009. PMID: 19297022 Review.
This phenotypic spectrum includes renal phenotypes, such as membranoproliferative glomerulonephritis and atypical hemolytic uremic syndrome, as well as ocular phenotypes, such as basal laminar drusen and age-related macular degeneration. In addition, several …
This phenotypic spectrum includes renal phenotypes, such as membranoproliferative glomerulonephritis and atypical hemolytic uremic syndrome, …
Short-term changes of Basal laminar drusen on spectral-domain optical coherence tomography.
van de Ven JP, Boon CJ, Smailhodzic D, Lechanteur YT, den Hollander AI, Hoyng CB, Theelen T. van de Ven JP, et al. Am J Ophthalmol. 2012 Sep;154(3):560-7. doi: 10.1016/j.ajo.2012.03.012. Epub 2012 May 23. Am J Ophthalmol. 2012. PMID: 22626619 Free article.
PURPOSE: To determine if small hard drusen in patients with basal laminar drusen show short-term changes. DESIGN: Prospective observational case series. METHODS: Ten subjects with basal laminar drusen were longitudinally followed d …
PURPOSE: To determine if small hard drusen in patients with basal laminar drusen show short-term changes. DESIGN: Prosp …
Clinical manifestations of cuticular drusen in Korean patients.
Shin DH, Kong M, Han G, Han JC, Ham DI. Shin DH, et al. Sci Rep. 2020 Jul 10;10(1):11469. doi: 10.1038/s41598-020-68493-2. Sci Rep. 2020. PMID: 32651454 Free PMC article.
Diffuse distribution was found in 61.7% and peripapillary involvement in 75.3% of eyes. Large drusen, drusenoid PED, GA, CNV, and AVL were observed in 59.3%, 26.5%, 18.5%, 3.7%, and 1.2% of eyes, respectively. ...
Diffuse distribution was found in 61.7% and peripapillary involvement in 75.3% of eyes. Large drusen, drusenoid PED, GA, CNV, and AVL were …
Drusen in patient-derived hiPSC-RPE models of macular dystrophies.
Galloway CA, Dalvi S, Hung SSC, MacDonald LA, Latchney LR, Wong RCB, Guymer RH, Mackey DA, Williams DS, Chung MM, Gamm DM, Pébay A, Hewitt AW, Singh R. Galloway CA, et al. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8214-E8223. doi: 10.1073/pnas.1710430114. Epub 2017 Sep 6. Proc Natl Acad Sci U S A. 2017. PMID: 28878022 Free PMC article.
Importantly basal deposits in patient hiPSC-RPE cultures were more abundant and displayed a lipid- and protein-rich "drusen-like" composition. Furthermore, increased accumulation of COL4 was observed in ECM isolated from control vs. patient hiPSC-RPE cultures. ...
Importantly basal deposits in patient hiPSC-RPE cultures were more abundant and displayed a lipid- and protein-rich "drusen-like" compositio …
Angiography features of early onset drusen.
Guigui B, Leveziel N, Martinet V, Massamba N, Sterkers M, Coscas G, Souied EH. Guigui B, et al. Br J Ophthalmol. 2011 Feb;95(2):238-44. doi: 10.1136/bjo.2009.178400. Epub 2010 Jul 7. Br J Ophthalmol. 2011. PMID: 20610475
AIMS: Drusen are rarely observed in patients < 50 years of age. Two types of early onset drusen (EOD) are commonly described: basal laminar drusen (BLD) and drusen associated with Malattia Leventinese (ML). ...

AIMS: Drusen are rarely observed in patients < 50 years of age. Two types of early onset drusen (EOD) are commonly described: b

…
Visual function and course of basal laminar drusen combined with vitelliform macular detachment.
Cohen SY, Meunier I, Soubrane G, Glacet-Bernard A, Coscas GJ. Cohen SY, et al. Br J Ophthalmol. 1994 Jun;78(6):437-40. doi: 10.1136/bjo.78.6.437. Br J Ophthalmol. 1994. PMID: 7520275 Free PMC article.
Basal laminar drusen (BLD) are small round yellow drusen that are more easily visualised angiographically than biomicroscopically, with a 'stars in the sky' pattern. ...Two thirds of cases of CNV were observed at the time of presentation; thus this fin …
Basal laminar drusen (BLD) are small round yellow drusen that are more easily visualised angiographically than biomicro …
THE ASSOCIATION BETWEEN CUTICULAR DRUSEN AND KIDNEY FUNCTION: A Population-Based Case-Control Study.
Høeg TB, Klein R, Moldow B, La Cour M, Klemp K, Erngaard D, Buch H, Ellervik C. Høeg TB, et al. Retina. 2016 May;36(5):896-900. doi: 10.1097/IAE.0000000000000808. Retina. 2016. PMID: 27115854
PURPOSE: To determine the association between cuticular drusen (CD) and kidney function. DESIGN: observational case-control study. SETTING: Population-based. Patients or Study Population: 53 participants with (CD) and 53 age- and sex-matched controls, selected from the Dan …
PURPOSE: To determine the association between cuticular drusen (CD) and kidney function. DESIGN: observational case-control study. SE …
18 results