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Page 1
Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries.
Logroscino G, Piccininni M, Graff C, Hardiman O, Ludolph AC, Moreno F, Otto M, Remes AM, Rowe JB, Seelaar H, Solje E, Stefanova E, Traykov L, Jelic V, Rydell MT, Pender N, Anderl-Straub S, Barandiaran M, Gabilondo A, Krüger J, Murley AG, Rittman T, van der Ende EL, van Swieten JC, Hartikainen P, Stojmenovic GM, Mehrabian S, Benussi L, Alberici A, Dell'Abate MT, Zecca C, Borroni B; FRONTIERS group. Logroscino G, et al. JAMA Neurol. 2023 Mar 1;80(3):279-286. doi: 10.1001/jamaneurol.2022.5128. JAMA Neurol. 2023. PMID: 36716024 Free PMC article.
DESIGN, SETTING, AND PARTICIPANTS: The Frontotemporal Dementia Incidence European Research Study (FRONTIERS) was a retrospective cohort study conducted from June 1, 2018, to May 31, 2019, using a population-based registry from 13 tertiary FTLD research clinics from the UK, the Ne …
DESIGN, SETTING, AND PARTICIPANTS: The Frontotemporal Dementia Incidence European Research Study (FRONTIERS) was a retrospective cohort stud …
Recognition of musical emotions in the behavioral variant of frontotemporal dementia.
Orjuela-Rojas JM, Montañés P, Rodríguez ILL, González-Marín NR. Orjuela-Rojas JM, et al. Rev Colomb Psiquiatr (Engl Ed). 2021 Apr-Jun;50(2):74-81. doi: 10.1016/j.rcpeng.2020.01.003. Rev Colomb Psiquiatr (Engl Ed). 2021. PMID: 34099256 English, Spanish.
INTRODUCTION: Multiple investigations have revealed that patients with behavioral variant of frontotemporal dementia (bvFTD) experience difficulty recognizing emotional signals in multiple processing modalities (e.g., faces, prosody). ...METHODS …
INTRODUCTION: Multiple investigations have revealed that patients with behavioral variant of frontotemporal d …
Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.
Seripa D, Solfrizzi V, Imbimbo BP, Daniele A, Santamato A, Lozupone M, Zuliani G, Greco A, Logroscino G, Panza F. Seripa D, et al. Expert Rev Neurother. 2016;16(3):259-77. doi: 10.1586/14737175.2016.1140039. Expert Rev Neurother. 2016. PMID: 26822031 Review.
MT chloride (also known as methylene blue) was investigated in a 24-week Phase II study in 321 mild-to-moderate AD patients at the doses of 69, 138, and 228 mg/day. This trial failed to show significant positive effects of MT in the overall patient population. ...A follow- …
MT chloride (also known as methylene blue) was investigated in a 24-week Phase II study in 321 mild-to-moderate AD patients at the doses of …
Clinical and MRI Predictors of Conversion From Mild Behavioural Impairment to Dementia.
Orso B, Mattei C, Arnaldi D, Massa F, Serafini G, Plantone D, Doglione E, Grafman J, Nobili F, Pardini M. Orso B, et al. Am J Geriatr Psychiatry. 2020 Jul;28(7):755-763. doi: 10.1016/j.jagp.2019.12.007. Epub 2019 Dec 17. Am J Geriatr Psychiatry. 2020. PMID: 31928846
METHODS: We retrospectively analyzed the cognitive performance and structural brain MRI of 113 subjects, with a clinical follow-up of at least 4 years available. Subjects were randomly assigned to a Group A (56 subjects; age: 65.4 7.9 years, 15 females, MMSE score: …
METHODS: We retrospectively analyzed the cognitive performance and structural brain MRI of 113 subjects, with a clinical follow-up of …
Prospective evaluation of behavioral scales in the behavioral variant of frontotemporal dementia.
Boutoleau-Bretonnière C, Lebouvier T, Volteau C, Jaulin P, Lacomblez L, Damier P, Thomas-Anterion C, Vercelletto M. Boutoleau-Bretonnière C, et al. Dement Geriatr Cogn Disord. 2012;34(2):75-82. doi: 10.1159/000341784. Epub 2012 Aug 23. Dement Geriatr Cogn Disord. 2012. PMID: 22922703
BACKGROUND: The Neuropsychiatric Inventory (NPI) and the Frontal Behavioral Inventory (FBI) are widely used in patients with the behavioral variant of frontotemporal dementia (bvFTD). Yet, few data are available on the long-term relevance of the …
BACKGROUND: The Neuropsychiatric Inventory (NPI) and the Frontal Behavioral Inventory (FBI) are widely used in patients with the behavior …
Cannabidiol in the management of bruxism in behavioral variant of frontotemporal degeneration.
Pina-Escudero SD, Okada de Oliveira M, Snyder A, Miller BL. Pina-Escudero SD, et al. Neurocase. 2021 Apr;27(2):209-211. doi: 10.1080/13554794.2021.1917620. Epub 2021 May 2. Neurocase. 2021. PMID: 33934685
Awake bruxism is an understudied feature of behavioral variant of frontotemporal dementia (bvFTD). We present the case of aman who presented with psychiatric, behavioral, cognitive changes, and teeth clenching that resulted in significant change …
Awake bruxism is an understudied feature of behavioral variant of frontotemporal dementia (bvFTD). We pre …
Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease.
Panza F, Solfrizzi V, Seripa D, Imbimbo BP, Lozupone M, Santamato A, Zecca C, Barulli MR, Bellomo A, Pilotto A, Daniele A, Greco A, Logroscino G. Panza F, et al. Biomed Res Int. 2016;2016:3245935. doi: 10.1155/2016/3245935. Epub 2016 Jun 26. Biomed Res Int. 2016. PMID: 27429978 Free PMC article. Review.
MT chloride (methylene blue) was investigated in a 24-week Phase II clinical trial in 321 patients with mild to moderate AD that failed to show significant positive effects in mild AD patients, although long-term observations (50 weeks) and biomarker studies suggest …
MT chloride (methylene blue) was investigated in a 24-week Phase II clinical trial in 321 patients with mild to moderate AD th …
Souvenaid reduces behavioral deficits and improves social cognition skills in frontotemporal dementia: a proof-of-concept study.
Pardini M, Serrati C, Guida S, Mattei C, Abate L, Massucco D, Sassos D, Amore M, Krueger F, Cocito L, Emberti Gialloreti L. Pardini M, et al. Neurodegener Dis. 2015;15(1):58-62. doi: 10.1159/000369811. Epub 2015 Jan 15. Neurodegener Dis. 2015. PMID: 25592742 Clinical Trial.
In line with this mechanism of action, Souvenaid has been shown to improve cognitive function in subjects with mild Alzheimer's disease in randomized clinical trials. To date, however, the potential of Souvenaid to improve cognitive functioning in subjects with othe …
In line with this mechanism of action, Souvenaid has been shown to improve cognitive function in subjects with mild Alzheimer's disease in …
Rationale and Design of the "DIagnostic and Prognostic Precision Algorithm for behavioral variant Frontotemporal Dementia" (DIPPA-FTD) Study: A Study Aiming to Distinguish Early Stage Sporadic FTD from Late-Onset Primary Psychiatric Disorders.
de Boer SCM, Riedl L, Fenoglio C, Rue I, Landin-Romero R, Matis S, Chatterton Z, Galimberti D, Halliday G, Diehl-Schmid J, Piguet O, Pijnenburg YAL, Ducharme S. de Boer SCM, et al. J Alzheimers Dis. 2024;97(2):963-973. doi: 10.3233/JAD-230829. J Alzheimers Dis. 2024. PMID: 38143357 Free PMC article.
BACKGROUND: The behavioral variant of frontotemporal dementia (bvFTD) is very heterogeneous in pathology, genetics, and disease course. ...Results will hopefully increase the ability to diagnose sporadic bvFTD in the early stage and predict prog …
BACKGROUND: The behavioral variant of frontotemporal dementia (bvFTD) is very heterogeneous in pathology, …
Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.
Binney RJ, Pankov A, Marx G, He X, McKenna F, Staffaroni AM, Kornak J, Attygalle S, Boxer AL, Schuff N, Gorno-Tempini ML, Weiner MW, Kramer JH, Miller BL, Rosen HJ. Binney RJ, et al. Brain Behav. 2017 Mar 23;7(4):e00675. doi: 10.1002/brb3.675. eCollection 2017 Apr. Brain Behav. 2017. PMID: 28413716 Free PMC article.
INTRODUCTION: Longitudinal imaging of neurodegenerative disorders is a potentially powerful biomarker for use in clinical trials. In Alzheimer's disease, studies have demonstrated that empirically derived regions of interest (ROIs) can provide more reliable measurement of …
INTRODUCTION: Longitudinal imaging of neurodegenerative disorders is a potentially powerful biomarker for use in clinical trials. In …
14 results