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Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubulin Polymerization: The Morpholine Position Matters.
Milunovic MNM, Ohui K, Besleaga I, Petrasheuskaya TV, Dömötör O, Enyedy ÉA, Darvasiova D, Rapta P, Barbieriková Z, Vegh D, Tóth S, Tóth J, Kucsma N, Szakács G, Popović-Bijelić A, Zafar A, Reynisson J, Shutalev AD, Bai R, Hamel E, Arion VB. Milunovic MNM, et al. Among authors: besleaga i. J Med Chem. 2024 Jun 13;67(11):9069-9090. doi: 10.1021/acs.jmedchem.4c00259. Epub 2024 May 21. J Med Chem. 2024. PMID: 38771959 Free PMC article.
Triapine Analogues and Their Copper(II) Complexes: Synthesis, Characterization, Solution Speciation, Redox Activity, Cytotoxicity, and mR2 RNR Inhibition.
Besleaga I, Stepanenko I, Petrasheuskaya TV, Darvasiova D, Breza M, Hammerstad M, Marć MA, Prado-Roller A, Spengler G, Popović-Bijelić A, Enyedy EA, Rapta P, Shutalev AD, Arion VB. Besleaga I, et al. Inorg Chem. 2021 Aug 2;60(15):11297-11319. doi: 10.1021/acs.inorgchem.1c01275. Epub 2021 Jul 19. Inorg Chem. 2021. PMID: 34279079 Free PMC article.