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568 results

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Page 1
Thalassemia.
Aydinok Y. Aydinok Y. Hematology. 2012 Apr;17 Suppl 1:S28-31. doi: 10.1179/102453312X13336169155295. Hematology. 2012. PMID: 22507773
Despite important advances on curative approaches such as stem cell transplantation and promising results of gene therapy, blood transfusions and iron chelation still remain as cornerstones of disease management. The purpose of this article is to focus on mainly the clinical …
Despite important advances on curative approaches such as stem cell transplantation and promising results of gene therapy, blood transfusion …
Thalassemia Status in Cambodia.
Sophâl C. Sophâl C. Hemoglobin. 2022 Jan;46(1):10-11. doi: 10.1080/03630269.2021.2008956. Hemoglobin. 2022. PMID: 35950584 Review.
The population of Cambodia (in 2019) was approximately 16 million with an annual growth rate of 1.4% in which the prevalence of hemoglobinopathies was estimated at about 40.0% (range 30.0-50.0%) to be carriers, and 2240 annual births for beta-thalassemia major …
The population of Cambodia (in 2019) was approximately 16 million with an annual growth rate of 1.4% in which the prevalence of hemoglobinop …
Retinal abnormalities in beta-thalassemia major.
Bhoiwala DL, Dunaief JL. Bhoiwala DL, et al. Surv Ophthalmol. 2016 Jan-Feb;61(1):33-50. doi: 10.1016/j.survophthal.2015.08.005. Epub 2015 Aug 29. Surv Ophthalmol. 2016. PMID: 26325202 Free PMC article. Review.
Patients with beta (beta)-thalassemia (beta-TM: beta-thalassemia major, beta-TI: beta-thalassemia intermedia) have a variety of complications that may affect all organs, including the eye. ...We will focus on retinal abnormalities present in individuals with …
Patients with beta (beta)-thalassemia (beta-TM: beta-thalassemia major, beta-TI: beta-thalassemia intermedia) have a va …
β-Thalassemia and ocular implications: a systematic review.
Liaska A, Petrou P, Georgakopoulos CD, Diamanti R, Papaconstantinou D, Kanakis MG, Georgalas I. Liaska A, et al. BMC Ophthalmol. 2016 Jul 8;16:102. doi: 10.1186/s12886-016-0285-2. BMC Ophthalmol. 2016. PMID: 27390837 Free PMC article. Review.
BACKGROUND: Beta-thalassemia is a severe genetic blood disorder caused by a mutation in the gene encoding for the beta chains of hemoglobin. Individuals with beta-thalassemia major require regular lifelong Red Blood Cell transfusions to survive. ...METHODS: E …
BACKGROUND: Beta-thalassemia is a severe genetic blood disorder caused by a mutation in the gene encoding for the beta chains of hemoglobin. …
Thalassemia: Common Clinical Queries in Management.
Lal A, Bansal D. Lal A, et al. Indian J Pediatr. 2020 Jan;87(1):75-81. doi: 10.1007/s12098-019-03065-5. Epub 2019 Oct 16. Indian J Pediatr. 2020. PMID: 31620986 Review.
Beta thalassemia major (TM) is the most frequent form of transfusion-dependent inherited anemia in India. ...Clinical decision making can be influenced by the perceived difficulty in access to a safe blood supply and the cost of therapy. ...
Beta thalassemia major (TM) is the most frequent form of transfusion-dependent inherited anemia in India. ...Clinica …
Pulmonary hypertension associated with thalassemia syndromes.
Fraidenburg DR, Machado RF. Fraidenburg DR, et al. Ann N Y Acad Sci. 2016 Mar;1368(1):127-39. doi: 10.1111/nyas.13037. Epub 2016 Mar 23. Ann N Y Acad Sci. 2016. PMID: 27008311 Free PMC article. Review.
Within the thalassemia syndromes, there are multiple mechanisms, both distinct and overlapping, by which PH develops and that differ among beta-thalassemia major or intermedia patients. PH in beta-thalassemia major correlates with the sev …
Within the thalassemia syndromes, there are multiple mechanisms, both distinct and overlapping, by which PH develops and that differ among …
beta-thalassemia intermedia: a clinical perspective.
Musallam KM, Taher AT, Rachmilewitz EA. Musallam KM, et al. Cold Spring Harb Perspect Med. 2012 Jul;2(7):a013482. doi: 10.1101/cshperspect.a013482. Cold Spring Harb Perspect Med. 2012. PMID: 22762026 Free PMC article. Review.
Earlier studies observed that patients with beta-thalassemia intermedia experience a clinical-complications profile that is different from that in patients with beta-thalassemia major. ...The effects of some therapeutic interventions on the development …
Earlier studies observed that patients with beta-thalassemia intermedia experience a clinical-complications profile that is different …
Hydroxyurea for lifelong transfusion-dependent β-thalassemia: A meta-analysis.
Algiraigri AH, Wright NAM, Paolucci EO, Kassam A. Algiraigri AH, et al. Pediatr Hematol Oncol. 2017 Nov;34(8):435-448. doi: 10.1080/08880018.2017.1354948. Epub 2018 Jan 16. Pediatr Hematol Oncol. 2017. PMID: 29337597 Review.
Growing literature over the last twenty years suggests promising results of the use HU in lifelong TDbetaT; however, its role and safety remain unanswered questions. The objective of this study was to evaluate the clinical efficacy and safety of HU in patients with lifelon …
Growing literature over the last twenty years suggests promising results of the use HU in lifelong TDbetaT; however, its role and safety rem …
Chelation therapy in beta-thalassemia: the benefits and limitations of desferrioxamine.
Giardina PJ, Grady RW. Giardina PJ, et al. Semin Hematol. 1995 Oct;32(4):304-12. Semin Hematol. 1995. PMID: 8560288 Review.
In summary, long-term studies of DFO therapy in multiply-transfused patients with beta-thalassemia major have clearly shown it to be generally safe and effective. ...
In summary, long-term studies of DFO therapy in multiply-transfused patients with beta-thalassemia major have clearly s …
568 results