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Quoted phrase not found in phrase index: "Blood xenobiotic"
Page 1
Drug-induced liver injury.
Andrade RJ, Chalasani N, Björnsson ES, Suzuki A, Kullak-Ublick GA, Watkins PB, Devarbhavi H, Merz M, Lucena MI, Kaplowitz N, Aithal GP. Andrade RJ, et al. Nat Rev Dis Primers. 2019 Aug 22;5(1):58. doi: 10.1038/s41572-019-0105-0. Nat Rev Dis Primers. 2019. PMID: 31439850 Free article. Review.
Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. ...A number of …
Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable even …
Revisited: Therapeutic and toxic blood concentrations of more than 1100 drugs and other xenobiotics.
Schulz M, Schmoldt A, Andresen-Streichert H, Iwersen-Bergmann S. Schulz M, et al. Crit Care. 2020 May 6;24(1):195. doi: 10.1186/s13054-020-02915-5. Crit Care. 2020. PMID: 32375836 Free PMC article. Review.
In addition, more than 200 substances, especially drugs who have been introduced since 2012 to the market as well as illegal drugs and other xenobiotics which became known to cause intoxications were added. We carefully referenced all data. Moreover, the annotations provid …
In addition, more than 200 substances, especially drugs who have been introduced since 2012 to the market as well as illegal drugs and other …
Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics.
Schulz M, Iwersen-Bergmann S, Andresen H, Schmoldt A. Schulz M, et al. Crit Care. 2012 Jul 26;16(4):R136. doi: 10.1186/cc11441. Crit Care. 2012. PMID: 22835221 Free PMC article. Review.
Moreover, the annotations providing details were completely revised and more than 100 annotations were added. RESULTS: For nearly 1,000 drugs and other xenobiotics, therapeutic ("normal") and, if data were available, toxic and comatose-fatal blood-plasma concentrati …
Moreover, the annotations providing details were completely revised and more than 100 annotations were added. RESULTS: For nearly 1,000 drug …
Metabolic alterations in multiple sclerosis and the impact of vitamin D supplementation.
Bhargava P, Fitzgerald KC, Calabresi PA, Mowry EM. Bhargava P, et al. JCI Insight. 2017 Oct 5;2(19):e95302. doi: 10.1172/jci.insight.95302. JCI Insight. 2017. PMID: 28978801 Free PMC article. Clinical Trial.
Generalized estimating equations models were used to assess change in WGCNA-identified module scores or metabolite pathways with vitamin D supplementation. RESULTS: Utilizing multiple analytical techniques, we identified metabolic alterations in oxidative stress (gamma-glu …
Generalized estimating equations models were used to assess change in WGCNA-identified module scores or metabolite pathways with vita …
Toxico-/biokinetics of nanomaterials.
Landsiedel R, Fabian E, Ma-Hock L, van Ravenzwaay B, Wohlleben W, Wiench K, Oesch F. Landsiedel R, et al. Arch Toxicol. 2012 Jul;86(7):1021-60. doi: 10.1007/s00204-012-0858-7. Epub 2012 May 11. Arch Toxicol. 2012. PMID: 22576463 Review.
In most studies with topical skin application, unintentional permeation and systemic availability were not observed; permeation for some NM with distinct properties was observed in animals. ...NM are typically not metabolized. Some NM cross the blood-brain ba …
In most studies with topical skin application, unintentional permeation and systemic availability were not observed; permeation for s …
Nephrotoxicity: Topical issue.
Gabelova A, Kozics K, Kapka-Skrzypczak L, Kruszewski M, Sramkova M. Gabelova A, et al. Mutat Res Genet Toxicol Environ Mutagen. 2019 Sep;845:402988. doi: 10.1016/j.mrgentox.2018.11.012. Epub 2018 Dec 6. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 31561894
Moreover, kidney injury can also occur as a consequence of exposures to environmental xenobiotics such as heavy metals, fungal toxins and nanomaterials. The lack of adequate in vitro human kidney models that mimic more realistically the in vivo conditions and the absence o …
Moreover, kidney injury can also occur as a consequence of exposures to environmental xenobiotics such as heavy metals, fungal toxins …
Is It Realistic to Propose Determination of a Lifetime Internal Exposome?
Sabbioni G, Berset JD, Day BW. Sabbioni G, et al. Chem Res Toxicol. 2020 Aug 17;33(8):2010-2021. doi: 10.1021/acs.chemrestox.0c00092. Epub 2020 Jul 16. Chem Res Toxicol. 2020. PMID: 32672951 Review.
Biomonitoring of xenobiotics has been performed for many years in occupational and environmental medicine. ...It is likely that only a small fraction of xenobiotics form such adducts. In addition, adduct analyses are more work intensive than the measurement of xe …
Biomonitoring of xenobiotics has been performed for many years in occupational and environmental medicine. ...It is likely that only …
Methodological Approaches to Evaluate Fetal Drug Exposure.
Bouazza N, Foissac F, Hirt D, Urien S, Benaboud S, Lui G, Treluyer JM. Bouazza N, et al. Curr Pharm Des. 2019;25(5):496-504. doi: 10.2174/1381612825666190319102812. Curr Pharm Des. 2019. PMID: 30892158 Review.
METHODS: To summarize the different methodologies developed towards the prediction of fetal drug exposure. RESULTS: Neonatal cord blood concentration is the most specific measurement of the transplacental drug transfer at the end of pregnancy. ...Some research group …
METHODS: To summarize the different methodologies developed towards the prediction of fetal drug exposure. RESULTS: Neonatal cord …
KLF15 regulates endobiotic and xenobiotic metabolism.
Han S, Ray JW, Pathak P, Sweet DR, Zhang R, Gao H, Jain N, Koritzinsky EH, Matoba K, Xu W, Chan ER, Simon DI, Jain MK. Han S, et al. Nat Metab. 2019 Apr;1(4):422-430. doi: 10.1038/s42255-019-0054-7. Epub 2019 Apr 8. Nat Metab. 2019. PMID: 32694878
Hepatic metabolism and elimination of endobiotics (for example, steroids, bile acids) and xenobiotics (for example, drugs, toxins) is essential for health. While the enzymatic (termed phase I-II) and transport machinery (termed phase III) controlling endobiotic and xeno …
Hepatic metabolism and elimination of endobiotics (for example, steroids, bile acids) and xenobiotics (for example, drugs, toxins) is …
Multiple Modes of Vitamin K Actions in Aging-Related Musculoskeletal Disorders.
Azuma K, Inoue S. Azuma K, et al. Int J Mol Sci. 2019 Jun 11;20(11):2844. doi: 10.3390/ijms20112844. Int J Mol Sci. 2019. PMID: 31212662 Free PMC article. Review.
Vitamin K is a fat-soluble vitamin that was originally found as an essential factor for blood coagulation. With the discovery of its role as a co-factor for gamma-glutamyl carboxylase (GGCX), its function for blood coagulation was understood as the activation of sev …
Vitamin K is a fat-soluble vitamin that was originally found as an essential factor for blood coagulation. With the discovery of its …
656 results