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Year Number of Results
1974 1
1977 1
1981 2
1982 2
1983 1
1984 2
1985 1
1986 3
1989 5
1990 5
1992 2
1993 3
1994 5
1995 8
1996 8
1997 8
1998 9
1999 6
2000 10
2001 21
2002 13
2003 26
2004 17
2005 19
2006 19
2007 18
2008 28
2009 12
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2014 25
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2016 31
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2024 9

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542 results

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Quoted phrase not found in phrase index: "Blood xenobiotic"
Page 1
Vitamin K and Osteoporosis.
Fusaro M, Cianciolo G, Brandi ML, Ferrari S, Nickolas TL, Tripepi G, Plebani M, Zaninotto M, Iervasi G, La Manna G, Gallieni M, Vettor R, Aghi A, Gasperoni L, Giannini S, Sella S, M Cheung A. Fusaro M, et al. Nutrients. 2020 Nov 25;12(12):3625. doi: 10.3390/nu12123625. Nutrients. 2020. PMID: 33255760 Free PMC article. Review.
Vitamin K acts as a coenzyme of carboxylase, catalyzing the carboxylation of several vitamin K dependent proteins. Beyond its well-known effects on blood coagulation, it also exerts relevant effects on bone and the vascular system. ...Another bone-related action of Vitamin …
Vitamin K acts as a coenzyme of carboxylase, catalyzing the carboxylation of several vitamin K dependent proteins. Beyond its well-known eff …
Drug-induced liver injury.
Andrade RJ, Chalasani N, Björnsson ES, Suzuki A, Kullak-Ublick GA, Watkins PB, Devarbhavi H, Merz M, Lucena MI, Kaplowitz N, Aithal GP. Andrade RJ, et al. Nat Rev Dis Primers. 2019 Aug 22;5(1):58. doi: 10.1038/s41572-019-0105-0. Nat Rev Dis Primers. 2019. PMID: 31439850 Free article. Review.
A number of clinical variables, validated in prospective cohorts, can be used to predict a more severe DILI outcome. Although no pharmacological therapy has been adequately tested in randomized clinical trials, corticosteroids can be useful, particularly in t …
A number of clinical variables, validated in prospective cohorts, can be used to predict a more severe DILI outcome. Although no phar …
Gut microbiome and type 2 diabetes: where we are and where to go?
Sharma S, Tripathi P. Sharma S, et al. J Nutr Biochem. 2019 Jan;63:101-108. doi: 10.1016/j.jnutbio.2018.10.003. Epub 2018 Oct 11. J Nutr Biochem. 2019. PMID: 30366260 Review.
Type 2 diabetes mellitus (T2D) is a highly prevalent metabolic disorder characterized by an imbalance in blood glucose level, altered lipid profile and high blood pressure. ...Thousands of the metabolites derived from microbes interact with the epithelial, hepatic a …
Type 2 diabetes mellitus (T2D) is a highly prevalent metabolic disorder characterized by an imbalance in blood glucose level, altered …
The shared biomarkers and pathways of systemic lupus erythematosus and metabolic syndrome analyzed by bioinformatics combining machine learning algorithm and single-cell sequencing analysis.
Wang Y, Huang Z, Xiao Y, Wan W, Yang X. Wang Y, et al. Front Immunol. 2022 Oct 19;13:1015882. doi: 10.3389/fimmu.2022.1015882. eCollection 2022. Front Immunol. 2022. PMID: 36341378 Free PMC article.
Those shared hub genes were associated with immunological and metabolic processes in peripheral blood. The scRNA-seq results verified that TNFSF13B and OAS1, possessing the highest diagnostic efficacy, were mainly expressed by monocytes. Additionally, they showed positive …
Those shared hub genes were associated with immunological and metabolic processes in peripheral blood. The scRNA-seq results verified …
Metabolic alterations in multiple sclerosis and the impact of vitamin D supplementation.
Bhargava P, Fitzgerald KC, Calabresi PA, Mowry EM. Bhargava P, et al. JCI Insight. 2017 Oct 5;2(19):e95302. doi: 10.1172/jci.insight.95302. JCI Insight. 2017. PMID: 28978801 Free PMC article. Clinical Trial.
RESULTS: Utilizing multiple analytical techniques, we identified metabolic alterations in oxidative stress (gamma-glutamyl amino acid, glutathione) and xenobiotic metabolism (benzoate, caffeine) in MS patients compared with healthy controls in the first cohort. ...CONCLUSI …
RESULTS: Utilizing multiple analytical techniques, we identified metabolic alterations in oxidative stress (gamma-glutamyl amino acid, gluta …
Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension.
Masaki T, Okazawa M, Asano R, Inagaki T, Ishibashi T, Yamagishi A, Umeki-Mizushima S, Nishimura M, Manabe Y, Ishibashi-Ueda H, Shirai M, Tsuchimochi H, Pearson JT, Kumanogoh A, Sakata Y, Ogo T, Kishimoto T, Nakaoka Y. Masaki T, et al. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2023899118. doi: 10.1073/pnas.2023899118. Proc Natl Acad Sci U S A. 2021. PMID: 33836606 Free PMC article.
Aryl hydrocarbon receptor (AHR), a nuclear receptor/transcription factor, detoxifies xenobiotics and regulates the differentiation and function of various immune cells. ...RNA-seq analysis, chromatin immunoprecipitation (ChIP)-seq analysis, immunohistochemical analysis, an …
Aryl hydrocarbon receptor (AHR), a nuclear receptor/transcription factor, detoxifies xenobiotics and regulates the differentiation an …
Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice.
Xu J, Wang X, Chen J, Chen S, Li Z, Liu H, Bai Y, Zhi F. Xu J, et al. Theranostics. 2020 Oct 30;10(26):12204-12222. doi: 10.7150/thno.47683. eCollection 2020. Theranostics. 2020. PMID: 33204338 Free PMC article.
RNA sequencing showed that T-MSC treatment contributed to colonic cell integrity and promoted xenobiotic metabolism. In vitro IGF-1 stimulation promoted the growth and proliferation of colon cells and organoids. ...
RNA sequencing showed that T-MSC treatment contributed to colonic cell integrity and promoted xenobiotic metabolism. In vitro IGF-1 s …
Toxico-/biokinetics of nanomaterials.
Landsiedel R, Fabian E, Ma-Hock L, van Ravenzwaay B, Wohlleben W, Wiench K, Oesch F. Landsiedel R, et al. Arch Toxicol. 2012 Jul;86(7):1021-60. doi: 10.1007/s00204-012-0858-7. Epub 2012 May 11. Arch Toxicol. 2012. PMID: 22576463 Review.
For toxicological testing and evaluation, information on the toxicokinetics of NM is essential as it is different from that of most other xenobiotics. This review provides an overview on the toxicokinetics of NM available to date. ...NM are prone to lymphatic transport, an …
For toxicological testing and evaluation, information on the toxicokinetics of NM is essential as it is different from that of most other …
Bystander activation and autoimmunity.
Pacheco Y, Acosta-Ampudia Y, Monsalve DM, Chang C, Gershwin ME, Anaya JM. Pacheco Y, et al. J Autoimmun. 2019 Sep;103:102301. doi: 10.1016/j.jaut.2019.06.012. Epub 2019 Jul 17. J Autoimmun. 2019. PMID: 31326230 Review.
Pathogens have been the most common antecedent events studied, but multiple other environmental factors including xenobiotic chemicals, drugs, vaccines, and nutritional factors have been implicated into the development of ADs. ...In all cases, we are cognizant of individua …
Pathogens have been the most common antecedent events studied, but multiple other environmental factors including xenobiotic chemical …
ABCG2: a perspective.
Robey RW, To KK, Polgar O, Dohse M, Fetsch P, Dean M, Bates SE. Robey RW, et al. Adv Drug Deliv Rev. 2009 Jan 31;61(1):3-13. doi: 10.1016/j.addr.2008.11.003. Epub 2008 Dec 16. Adv Drug Deliv Rev. 2009. PMID: 19135109 Free PMC article. Review.
With high normal tissue expression in the brain endothelium, gastrointestinal tract, and placenta, ABCG2 is believed to be important in the protection from xenobiotics, regulating oral bioavailability, forming part of the blood-brain barrier, the blood-testis …
With high normal tissue expression in the brain endothelium, gastrointestinal tract, and placenta, ABCG2 is believed to be important in the …
542 results