Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2001 1
2005 3
2014 1
2015 1
2016 3
2018 2
2019 2
2020 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

13 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Body mass index quantitative trait locus 10"
Page 1
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, Zhu G, Macé A, Sidore C, Trompet S, Mangino M, Sabater-Lleal M, Kemp JP, Abbasi A, Kacprowski T, Verweij N, Smith AV, Huang T, Marzi C, Feitosa MF, Lohman KK, Kleber ME, Milaneschi Y, Mueller C, Huq M, Vlachopoulou E, Lyytikäinen LP, Oldmeadow C, Deelen J, Perola M, Zhao JH, Feenstra B; LifeLines Cohort Study; Amini M; CHARGE Inflammation Working Group; Lahti J, Schraut KE, Fornage M, Suktitipat B, Chen WM, Li X, Nutile T, Malerba G, Luan J, Bak T, Schork N, Del Greco M F, Thiering E, Mahajan A, Marioni RE, Mihailov E, Eriksson J, Ozel AB, Zhang W, Nethander M, Cheng YC, Aslibekyan S, Ang W, Gandin I, Yengo L, Portas L, Kooperberg C, Hofer E, Rajan KB, Schurmann C, den Hollander W, Ahluwalia TS, Zhao J, Draisma HHM, Ford I, Timpson N, Teumer A, Huang H, Wahl S, Liu Y, Huang J, Uh HW, Geller F, Joshi PK, Yanek LR, Trabetti E, Lehne B, Vozzi D, Verbanck M, Biino G, Saba Y, Meulenbelt I, O'Connell JR, Laakso M, Giulianini F, Magnusson PKE, Ballantyne CM, Hottenga JJ, Montgomery GW, Rivadineira F, Rueedi R, Steri M, Herzig KH, S… See abstract for full author list ➔ Ligthart S, et al. Am J Hum Genet. 2018 Nov 1;103(5):691-706. doi: 10.1016/j.ajhg.2018.09.009. Am J Hum Genet. 2018. PMID: 30388399 Free PMC article.

Additionally, we performed in silico functional analyses and Mendelian randomization analyses with several clinical outcomes. The GWAS meta-analyses of CRP revealed 58 distinct genetic loci (p < 5 10(-8)). After adjustment for body mass index

…
Additionally, we performed in silico functional analyses and Mendelian randomization analyses with several clinical outcomes. The GWAS meta- …
Advances in Exercise, Fitness, and Performance Genomics in 2015.
Sarzynski MA, Loos RJ, Lucia A, Pérusse L, Roth SM, Wolfarth B, Rankinen T, Bouchard C. Sarzynski MA, et al. Med Sci Sports Exerc. 2016 Oct;48(10):1906-16. doi: 10.1249/MSS.0000000000000982. Med Sci Sports Exerc. 2016. PMID: 27183119 Review.
One study used a quantitative trait locus for wheel running in mice to identify single nucleotide polymorphisms (SNPs) in humans associated with physical activity levels. ...Several studies examined gene-physical activity interactions on cardiometabolic trait …
One study used a quantitative trait locus for wheel running in mice to identify single nucleotide polymorphisms (SNPs) …
Genetics of insulin resistance.
Pedersen O. Pedersen O. Exp Clin Endocrinol Diabetes. 1999;107(2):113-8. doi: 10.1055/s-0029-1212085. Exp Clin Endocrinol Diabetes. 1999. PMID: 10320051 Review.
Three complementary approaches have been applied in the search for mutations: mutational analysis of candidate genes; linkage analysis of candidate genes or chromosomal regions for insulin resistance in familial type 2 diabetes; and random genome mapping with quantitative …
Three complementary approaches have been applied in the search for mutations: mutational analysis of candidate genes; linkage analysis of ca …
Glycated Serum Protein Genetics and Pleiotropy with Cardiometabolic Risk Factors.
Johnson MP, Keyho R, Blackburn NB, Laston S, Kumar S, Peralta J, Thapa SS, Towne B, Subedi J, Blangero J, Williams-Blangero S. Johnson MP, et al. J Diabetes Res. 2019 Apr 4;2019:2310235. doi: 10.1155/2019/2310235. eCollection 2019. J Diabetes Res. 2019. PMID: 31089471 Free PMC article.
Additive genetic effects significantly influence variation in GSP and %GA levels (p values: 1.15 10(-5) and 3.39 10(-5), respectively). We localized a significant (LOD score = 3.18) and novel GSP QTL on chromosome 11q, which has been previously linked to type 2 diab …
Additive genetic effects significantly influence variation in GSP and %GA levels (p values: 1.15 10(-5) and 3.39 10(-5), respe …
Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci.
Rahmioglu N, Macgregor S, Drong AW, Hedman ÅK, Harris HR, Randall JC, Prokopenko I; International Endogene Consortium (IEC), The GIANT Consortium; Nyholt DR, Morris AP, Montgomery GW, Missmer SA, Lindgren CM, Zondervan KT. Rahmioglu N, et al. Hum Mol Genet. 2015 Feb 15;24(4):1185-99. doi: 10.1093/hmg/ddu516. Epub 2014 Oct 8. Hum Mol Genet. 2015. PMID: 25296917 Free PMC article.
Endometriosis is a chronic inflammatory condition in women that results in pelvic pain and subfertility, and has been associated with decreased body mass index (BMI). Genetic variants contributing to the heritable component have started to emerge from genome- …
Endometriosis is a chronic inflammatory condition in women that results in pelvic pain and subfertility, and has been associated with decrea …
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.
Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, Bressler J, Ward-Caviness CK, Chen BH, Huan T, Bakulski K, Salfati EL; WHI-EMPC Investigators; Fiorito G; CHARGE epigenetics of Coronary Heart Disease; Wahl S, Schramm K, Sha J, Hernandez DG, Just AC, Smith JA, Sotoodehnia N, Pilling LC, Pankow JS, Tsao PS, Liu C, Zhao W, Guarrera S, Michopoulos VJ, Smith AK, Peters MJ, Melzer D, Vokonas P, Fornage M, Prokisch H, Bis JC, Chu AY, Herder C, Grallert H, Yao C, Shah S, McRae AF, Lin H, Horvath S, Fallin D, Hofman A, Wareham NJ, Wiggins KL, Feinberg AP, Starr JM, Visscher PM, Murabito JM, Kardia SL, Absher DM, Binder EB, Singleton AB, Bandinelli S, Peters A, Waldenberger M, Matullo G, Schwartz JD, Demerath EW, Uitterlinden AG, van Meurs JB, Franco OH, Chen YI, Levy D, Turner ST, Deary IJ, Ressler KJ, Dupuis J, Ferrucci L, Ong KK, Assimes TL, Boerwinkle E, Koenig W, Arnett DK, Baccarelli AA, Benjamin EJ, Dehghan A. Ligthart S, et al. Genome Biol. 2016 Dec 12;17(1):255. doi: 10.1186/s13059-016-1119-5. Genome Biol. 2016. PMID: 27955697 Free PMC article.

We found differential methylation at 218 CpG sites to be associated with CRP (P < 1.15 10(-7)) in the discovery panel of European ancestry and replicated (P < 2.29 10(-4)) 58 CpG sites (45 unique loci) among African Americans. ...DNA methylation at nine

…

We found differential methylation at 218 CpG sites to be associated with CRP (P < 1.15 10(-7)) in the discovery panel of European

…
Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.
Galván-Femenía I, Obón-Santacana M, Piñeyro D, Guindo-Martinez M, Duran X, Carreras A, Pluvinet R, Velasco J, Ramos L, Aussó S, Mercader JM, Puig L, Perucho M, Torrents D, Moreno V, Sumoy L, de Cid R. Galván-Femenía I, et al. J Med Genet. 2018 Nov;55(11):765-778. doi: 10.1136/jmedgenet-2018-105437. Epub 2018 Aug 30. J Med Genet. 2018. PMID: 30166351 Free PMC article.
RESULTS: Heritability estimates (eg, skin colour, alcohol consumption, smoking habit, body mass index, educational level or height) revealed an important contribution of SNP variants, ranging from 18% to 77%. Single-trait analysis identified 1785 SNPs …
RESULTS: Heritability estimates (eg, skin colour, alcohol consumption, smoking habit, body mass index, educational leve …
Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2.
Luo A, Jung J, Longley M, Rosoff DB, Charlet K, Muench C, Lee J, Hodgkinson CA, Goldman D, Horvath S, Kaminsky ZA, Lohoff FW. Luo A, et al. Neuropsychopharmacology. 2020 Jan;45(2):327-336. doi: 10.1038/s41386-019-0500-y. Epub 2019 Aug 29. Neuropsychopharmacology. 2020. PMID: 31466081 Free PMC article.
We followed up on relevant top findings with in silico expression quantitative trait loci (eQTL) analyses for biological function using the BRAINEAC database. There was a 2.22-year age acceleration in AUD compared to controls after adjusting for gender and bl …
We followed up on relevant top findings with in silico expression quantitative trait loci (eQTL) analyses for biologica …
Genome-wide linkage analysis of pulse pressure in Mexican Americans.
Atwood LD, Samollow PB, Hixson JE, Stern MP, MacCluer JW. Atwood LD, et al. Hypertension. 2001 Feb;37(2 Pt 2):425-8. doi: 10.1161/01.hyp.37.2.425. Hypertension. 2001. PMID: 11230312
The single-locus component included sex-specific and genotype-specific effects of both age and body mass index. ...The model that contained only the polygenic component and simple effects of the covariates showed pulse pressure heritability of 0.21. Wh …
The single-locus component included sex-specific and genotype-specific effects of both age and body mass index. …
The Pro12Ala and C-681G variants of the PPARG locus are associated with opposing growth phenotypes in young schoolchildren.
Cecil JE, Fischer B, Doney AS, Hetherington M, Watt P, Wrieden W, Bolton-Smith C, Palmer CN. Cecil JE, et al. Diabetologia. 2005 Aug;48(8):1496-502. doi: 10.1007/s00125-005-1817-0. Epub 2005 Jul 9. Diabetologia. 2005. PMID: 16007414 Free article.
METHODS: Height and weight were recorded for 2454 prepubertal children aged between 4 and 10 years, who were then genotyped for three common variants of the PPARG locus: C-681G, Pro12Ala and C1431T. ...CONCLUSIONS/INTERPRETATION: This study demonstrates that quan …
METHODS: Height and weight were recorded for 2454 prepubertal children aged between 4 and 10 years, who were then genotyped for three …
13 results