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Quoted phrase not found in phrase index: "Bone marrow failure syndrome 5"
Page 1
Hepatitis-Associated Aplastic Anemia.
Alshaibani A, Dufour C, Risitano A, de Latour R, Aljurf M. Alshaibani A, et al. Hematol Oncol Stem Cell Ther. 2022 Jun 1;15(2):8-12. doi: 10.1016/j.hemonc.2020.10.001. Hematol Oncol Stem Cell Ther. 2022. PMID: 33197413 Review.
Hepatitis-associated aplastic anemia (HAAA) is a rare illness, characterized by onset of pancytopenia with a hypoplastic bone marrow that traditionally occurs within 6 months of an increase in serum aminotransferases. HAAA is observed in 1% to 5% of all newly …
Hepatitis-associated aplastic anemia (HAAA) is a rare illness, characterized by onset of pancytopenia with a hypoplastic bone marr …
Horse versus rabbit antithymocyte globulin in acquired aplastic anemia.
Scheinberg P, Nunez O, Weinstein B, Scheinberg P, Biancotto A, Wu CO, Young NS. Scheinberg P, et al. N Engl J Med. 2011 Aug 4;365(5):430-8. doi: 10.1056/NEJMoa1103975. N Engl J Med. 2011. PMID: 21812672 Free PMC article. Clinical Trial.
BACKGROUND: In severe acquired aplastic anemia, hematopoietic failure is the result of immune-mediated destruction of bone marrow stem and progenitor cells. ...Although horse ATG is the standard therapy, rabbit ATG is more potent in depleting peripheral-blood …
BACKGROUND: In severe acquired aplastic anemia, hematopoietic failure is the result of immune-mediated destruction of bone …
Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial.
DeZern AE, Eapen M, Wu J, Talano JA, Solh M, Dávila Saldaña BJ, Karanes C, Horwitz ME, Mallhi K, Arai S, Farhadfar N, Hexner E, Westervelt P, Antin JH, Deeg HJ, Leifer E, Brodsky RA, Logan BR, Horowitz MM, Jones RJ, Pulsipher MA. DeZern AE, et al. Lancet Haematol. 2022 Sep;9(9):e660-e669. doi: 10.1016/S2352-3026(22)00206-X. Epub 2022 Jul 27. Lancet Haematol. 2022. PMID: 35907408 Free PMC article. Clinical Trial.
This study aimed to understand the 1-year overall survival in patients with relapsed or refractory severe aplastic anaemia after haploidentical bone marrow transplantation. METHODS: We report the outcomes of BMT CTN 1502, a single-arm, phase 2 clinical tri …
This study aimed to understand the 1-year overall survival in patients with relapsed or refractory severe aplastic anaemia after haploidenti …
Aplastic anemia.
Čermák J. Čermák J. Vnitr Lek. 2018 Summer;64(5):501-507. Vnitr Lek. 2018. PMID: 30193518 English.
Aplastic anemia - bone marrow failure (AA) is defined as pancytopenia with hypocellular bone marrow without signs of marrow fibrosis or of presence of abnormal cells. ...Toxic agent leads to expression of neoantigens or cryptic antigens o …
Aplastic anemia - bone marrow failure (AA) is defined as pancytopenia with hypocellular bone marrow witho …
Hepatitis-associated Aplastic Anemia.
Gonnot M, Neumann F, Huet F, Maudinas R, Leblanc T, Lacaille F. Gonnot M, et al. J Pediatr Gastroenterol Nutr. 2022 Nov 1;75(5):553-555. doi: 10.1097/MPG.0000000000003603. Epub 2022 Sep 6. J Pediatr Gastroenterol Nutr. 2022. PMID: 36070526
Eltrombopag with or without Tacrolimus for relapsed/refractory acquired aplastic anaemia: a prospective randomized trial.
Ji J, Wan Z, Ruan J, Yang Y, Hu Q, Chen Z, Yang C, Chen M, Han B. Ji J, et al. Blood Cancer J. 2023 Sep 19;13(1):146. doi: 10.1038/s41408-023-00921-8. Blood Cancer J. 2023. PMID: 37726286 Free PMC article. Clinical Trial.
This trial compared eltrombopag (EPAG)+tacrolimus and EPAG monotherapy in patients with refractory/relapsed acquired aplastic anaemia (AA). ...With a median follow-up of 18 (6-24) months, the overall response rate (ORR) for patients treated with EPAG+tacrolimus and EPAG al …
This trial compared eltrombopag (EPAG)+tacrolimus and EPAG monotherapy in patients with refractory/relapsed acquired aplastic anaemia …
Long-term eltrombopag for bone marrow failure depletes iron.
Young DJ, Fan X, Groarke EM, Patel B, Desmond R, Winkler T, Larochelle A, Calvo KR, Young NS, Dunbar CE. Young DJ, et al. Am J Hematol. 2022 Jun 1;97(6):791-801. doi: 10.1002/ajh.26543. Epub 2022 Mar 26. Am J Hematol. 2022. PMID: 35312200 Free PMC article.
We conducted a retrospective review of patients treated at the NIH for aplastic anemia, myelodysplastic syndrome, and unilineage cytopenias, comparing those treated with EPAG to a historical cohort treated with immunosuppression without EPAG. ...Baseline ferritin did not c …
We conducted a retrospective review of patients treated at the NIH for aplastic anemia, myelodysplastic syndrome, and unilineage cyto …
Haploidentical bone marrow transplants with post transplant cyclophosphamide on day + 3 + 5: The Genova protocol.
Raiola AM, Angelucci E, Sica S, Bacigalupo A. Raiola AM, et al. Blood Rev. 2023 Nov;62:101031. doi: 10.1016/j.blre.2022.101031. Epub 2022 Nov 11. Blood Rev. 2023. PMID: 36435691 Review.
We report 634 patients who underwent unmanipulated haploidentical (HAPLO) bone marrow transplantation (BMT) in two Centers. The diagnosis was acute myeloid leukemia (AML) (n = 251), acute lymphoblastic leukemia (ALL)(n = 107), myelodysplastic syndrome and mye …
We report 634 patients who underwent unmanipulated haploidentical (HAPLO) bone marrow transplantation (BMT) in two Centers. Th …
Pediatric bone marrow failure: Clinical, hematological and targeted next generation sequencing data.
Chhabra P, Bhatia P, Singh M, Bansal D, Jain R, Varma N, Trehan A. Chhabra P, et al. Blood Cells Mol Dis. 2021 Mar;87:102510. doi: 10.1016/j.bcmd.2020.102510. Epub 2020 Nov 5. Blood Cells Mol Dis. 2021. PMID: 33197791
RESULTS: We identified causative mutation in overall 15 of 27 tested children (55.5%) in group 1 and 2 of 15 tested children (13.3%) in group 2. In DBA, a mutation was noted in 50% cases with involvement of RPS 19 (75%) and RPL5 (25%) genes. Phenotypic abnormalities were p …
RESULTS: We identified causative mutation in overall 15 of 27 tested children (55.5%) in group 1 and 2 of 15 tested children (13.3%) …
Efficacy of Eltrombopag with Immunosuppressive Therapy Versus Immunosuppressive Therapy Alone on Severe Aplastic Anaemia: A Systematic Review and Meta-analysis.
Zhang S, Wang Q, Cui K, Cheng B, Fan J, Hu S. Zhang S, et al. Clin Drug Investig. 2023 May;43(5):315-324. doi: 10.1007/s40261-023-01266-7. Epub 2023 May 11. Clin Drug Investig. 2023. PMID: 37165250 Free PMC article.
BACKGROUND AND OBJECTIVE: Severe aplastic anaemia (SAA) is a syndrome of bone marrow failure caused by T cell-mediated destruction of haematopoietic stem cells and progenitor cells. ...METHODS: We performed this meta-analysis by retrieving studies that …
BACKGROUND AND OBJECTIVE: Severe aplastic anaemia (SAA) is a syndrome of bone marrow failure caused by T cell-me …
1,874 results