Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
Arsiwala T, Pahla J, van Tits LJ, Bisceglie L, Gaul DS, Costantino S, Miranda MX, Nussbaum K, Stivala S, Blyszczuk P, Weber J, Tailleux A, Stein S, Paneni F, Beer JH, Greter M, Becher B, Mostoslavsky R, Eriksson U, Staels B, Auwerx J, Hottiger MO, Lüscher TF, Matter CM.
Arsiwala T, et al.
J Mol Cell Cardiol. 2020 Feb;139:24-32. doi: 10.1016/j.yjmcc.2020.01.002. Epub 2020 Jan 21.
J Mol Cell Cardiol. 2020.
PMID: 31972266
We determined the effects of bone marrow-restricted Sirt6 deletion on foam cell formation and atherogenesis using a mouse model. METHODS AND RESULTS: Sirt6 deletion in bone marrow-derived cells increased aortic plaques, lipid content and …
We determined the effects of bone marrow-restricted Sirt6 deletion on foam cell formation and atherogenesis using a mou …