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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1979 4
1980 3
1981 3
1982 6
1983 3
1984 2
1985 7
1986 13
1987 5
1988 6
1989 15
1990 11
1991 8
1992 15
1993 23
1994 16
1995 22
1996 23
1997 19
1998 21
1999 22
2000 34
2001 30
2002 30
2003 43
2004 57
2005 63
2006 59
2007 70
2008 84
2009 102
2010 116
2011 102
2012 141
2013 132
2014 157
2015 159
2016 182
2017 199
2018 188
2019 181
2020 182
2021 193
2022 210
2023 195
2024 75

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2,767 results

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Page 1
Hearing impairment is associated with cognitive decline, brain atrophy and tau pathology.
Wang HF, Zhang W, Rolls ET; Alzheimer's Disease Neuroimaging Initiative; Li Y, Wang L, Ma YH, Kang J, Feng J, Yu JT, Cheng W. Wang HF, et al. EBioMedicine. 2022 Dec;86:104336. doi: 10.1016/j.ebiom.2022.104336. Epub 2022 Nov 7. EBioMedicine. 2022. PMID: 36356475 Free PMC article.
Moreover, hearing impairment was correlated with a high level of CSF tau protein in the CABLE study and in the ADNI database. Finally, mediation analyses showed that brain atrophy and tau pathology partly mediated the association between hearing impairment and cogni …
Moreover, hearing impairment was correlated with a high level of CSF tau protein in the CABLE study and in the ADNI database. Finally, media …
Effect of Probiotic Bifidobacterium breve in Improving Cognitive Function and Preventing Brain Atrophy in Older Patients with Suspected Mild Cognitive Impairment: Results of a 24-Week Randomized, Double-Blind, Placebo-Controlled Trial.
Asaoka D, Xiao J, Takeda T, Yanagisawa N, Yamazaki T, Matsubara Y, Sugiyama H, Endo N, Higa M, Kasanuki K, Ichimiya Y, Koido S, Ohno K, Bernier F, Katsumata N, Nagahara A, Arai H, Ohkusa T, Sato N. Asaoka D, et al. J Alzheimers Dis. 2022;88(1):75-95. doi: 10.3233/JAD-220148. J Alzheimers Dis. 2022. PMID: 35570493 Free PMC article. Clinical Trial.
OBJECTIVE: We investigated the effect of the probiotic strain Bifidobacterium breve MCC1274 (A1) in enhancing cognition and preventing brain atrophy of older patients with mild cognitive impairment (MCI). ...Cognitive functions were assessed by ADAS-Jcog and MMSE te …
OBJECTIVE: We investigated the effect of the probiotic strain Bifidobacterium breve MCC1274 (A1) in enhancing cognition and preventing br …
The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS).
Kaplan A, Zelicha H, Yaskolka Meir A, Rinott E, Tsaban G, Levakov G, Prager O, Salti M, Yovell Y, Ofer J, Huhn S, Beyer F, Witte V, Villringer A, Meiran N, B Emesh T, Kovacs P, von Bergen M, Ceglarek U, Blüher M, Stumvoll M, Hu FB, Stampfer MJ, Friedman A, Shelef I, Avidan G, Shai I. Kaplan A, et al. Am J Clin Nutr. 2022 May 1;115(5):1270-1281. doi: 10.1093/ajcn/nqac001. Am J Clin Nutr. 2022. PMID: 35021194 Free PMC article. Clinical Trial.
BACKGROUND: The effect of diet on age-related brain atrophy is largely unproven. OBJECTIVES: We aimed to explore the effect of a Mediterranean diet (MED) higher in polyphenols and lower in red/processed meat (Green-MED diet) on age-related brain atrophy …
BACKGROUND: The effect of diet on age-related brain atrophy is largely unproven. OBJECTIVES: We aimed to explore the effect of …
Association between pseudoexfoliation and Alzheimer's disease-related brain atrophy.
Jeong WC, Min JY, Kang TG, Bae H. Jeong WC, et al. PLoS One. 2023 Jun 8;18(6):e0286727. doi: 10.1371/journal.pone.0286727. eCollection 2023. PLoS One. 2023. PMID: 37289754 Free PMC article. Review.
PEX deposition shares features with amyloid aggregation in AD, and brain atrophy is a common AD feature, with beta-amyloid accumulation among contributing factors. ...Patients with PEX were divided into two groups: with and without glaucoma. The main outcome measure …
PEX deposition shares features with amyloid aggregation in AD, and brain atrophy is a common AD feature, with beta-amyloid acc …
Brain atrophy in prodromal synucleinopathy is shaped by structural connectivity and gene expression.
Rahayel S, Tremblay C, Vo A, Zheng YQ, Lehéricy S, Arnulf I, Vidailhet M, Corvol JC; ICEBERG Study Group; Gagnon JF, Postuma RB, Montplaisir J, Lewis S, Matar E, Ehgoetz Martens K, Borghammer P, Knudsen K, Hansen A, Monchi O, Misic B, Dagher A. Rahayel S, et al. Brain. 2022 Sep 14;145(9):3162-3178. doi: 10.1093/brain/awac187. Brain. 2022. PMID: 35594873
Most iRBD patients develop dementia with Lewy bodies, Parkinson's disease or multiple system atrophy over time. Patients with iRBD exhibit brain atrophy patterns that are reminiscent of those observed in overt synucleinopathies. However, the mechanisms linking br …
Most iRBD patients develop dementia with Lewy bodies, Parkinson's disease or multiple system atrophy over time. Patients with iRBD exhibit …
Novel data-driven subtypes and stages of brain atrophy in the ALS-FTD spectrum.
Shen T, Vogel JW, Duda J, Phillips JS, Cook PA, Gee J, Elman L, Quinn C, Amado DA, Baer M, Massimo L, Grossman M, Irwin DJ, McMillan CT. Shen T, et al. Transl Neurodegener. 2023 Dec 7;12(1):57. doi: 10.1186/s40035-023-00389-3. Transl Neurodegener. 2023. PMID: 38062485 Free PMC article.
RESULTS: SuStaIn identified three novel subtypes: two disease subtypes with predominant brain atrophy in either prefrontal/somatomotor regions or limbic-related regions, and a normal-appearing group without obvious brain atrophy. ...CONCLUSIONS: Our fi …
RESULTS: SuStaIn identified three novel subtypes: two disease subtypes with predominant brain atrophy in either prefrontal/som …
Homocysteine and brain atrophy.
Sachdev PS. Sachdev PS. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Sep;29(7):1152-61. doi: 10.1016/j.pnpbp.2005.06.026. Prog Neuropsychopharmacol Biol Psychiatry. 2005. PMID: 16102882 Review.
Homocysteine (Hcy) has been implicated as a risk factor for vascular disease as well as brain atrophy. There is evidence to implicate Hcy in increased oxidative stress, DNA damage, the triggering of apoptosis and excitotoxicity, all important mechanisms in neurodege …
Homocysteine (Hcy) has been implicated as a risk factor for vascular disease as well as brain atrophy. There is evidence to im …
Nutrients, Cognitive Function, and Brain Aging: What We Have Learned from Dogs.
Pan Y. Pan Y. Med Sci (Basel). 2021 Nov 18;9(4):72. doi: 10.3390/medsci9040072. Med Sci (Basel). 2021. PMID: 34842769 Free PMC article. Review.
Both AD and CDS are incurable diseases at this moment, therefore more efforts should be focused on preventing or reducing brain atrophy and minimizing the risk of AD in people and CDS in dogs. Since brain atrophy leads to irreversible cognitive decline …
Both AD and CDS are incurable diseases at this moment, therefore more efforts should be focused on preventing or reducing brain at …
Triphasic waves and brain atrophy in patients with acute encephalopathy.
Merchán Del Hierro X, Persi G, Rojas G, Gatto E, Pereira de Silva N. Merchán Del Hierro X, et al. Colomb Med (Cali). 2022 Jun 30;53(2):e2034500. doi: 10.25100/cm.v53i2.4500. eCollection 2022 Apr-Jun. Colomb Med (Cali). 2022. PMID: 36415695 Free PMC article.
INTRODUCTION: Triphasic waves (TW) constitute an electroencephalographic pattern associated with certain kinds of encephalopathy. Brain atrophy may be a predisposing factor linked with TW. OBJECTIVE: To compare the degree of brain atrophy and white mat …
INTRODUCTION: Triphasic waves (TW) constitute an electroencephalographic pattern associated with certain kinds of encephalopathy. Brain …
Aging and Brain Atrophy in Multiple Sclerosis.
Ghione E, Bergsland N, Dwyer MG, Hagemeier J, Jakimovski D, Paunkoski I, Ramasamy DP, Carl E, Hojnacki D, Kolb C, Weinstock-Guttman B, Zivadinov R. Ghione E, et al. J Neuroimaging. 2019 Jul;29(4):527-535. doi: 10.1111/jon.12625. Epub 2019 May 10. J Neuroimaging. 2019. PMID: 31074192
BACKGROUND AND PURPOSE: Brain atrophy accelerates at the age of 60 in healthy individuals (HI) and at disease onset in multiple sclerosis (MS) patients. Whether there is an exacerbating effect of aging superimposed on MS-related brain atrophy is unknow …
BACKGROUND AND PURPOSE: Brain atrophy accelerates at the age of 60 in healthy individuals (HI) and at disease onset in multipl …
2,767 results