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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
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1971 1
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1974 2
1975 4
1976 2
1977 6
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1979 13
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1981 11
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1983 14
1984 14
1985 14
1986 11
1987 11
1988 16
1989 17
1990 25
1991 17
1992 35
1993 25
1994 26
1995 35
1996 46
1997 35
1998 41
1999 41
2000 49
2001 42
2002 45
2003 55
2004 58
2005 75
2006 78
2007 79
2008 80
2009 65
2010 93
2011 112
2012 104
2013 90
2014 100
2015 134
2016 148
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2019 195
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2,699 results

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Quoted phrase not found in phrase index: "Brain small vessel disease 1 with or without ocular anomalies"
Page 1
Small vessel disease: mechanisms and clinical implications.
Wardlaw JM, Smith C, Dichgans M. Wardlaw JM, et al. Lancet Neurol. 2019 Jul;18(7):684-696. doi: 10.1016/S1474-4422(19)30079-1. Epub 2019 May 13. Lancet Neurol. 2019. PMID: 31097385 Review.
Small vessel disease is a disorder of cerebral microvessels that causes white matter hyperintensities and several other common abnormalities (eg, recent small subcortical infarcts and lacunes) seen on brain imaging. ...This knowledge will …
Small vessel disease is a disorder of cerebral microvessels that causes white matter hyperintensities and several other …
Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease: A Mendelian Randomization Study.
Georgakis MK, Harshfield EL, Malik R, Franceschini N, Langenberg C, Wareham NJ, Markus HS, Dichgans M. Georgakis MK, et al. Neurology. 2021 Mar 30;96(13):e1732-e1742. doi: 10.1212/WNL.0000000000011555. Epub 2021 Jan 25. Neurology. 2021. PMID: 33495378 Free PMC article.
We further found associations of genetic predisposition to insulin resistance with large artery and small vessel stroke, whereas predisposition to beta-cell dysfunction was associated with small vessel stroke, intracerebral hemorrhage, lower gray matte …
We further found associations of genetic predisposition to insulin resistance with large artery and small vessel stroke, where …
Overcoming the blood-brain tumor barrier for effective glioblastoma treatment.
van Tellingen O, Yetkin-Arik B, de Gooijer MC, Wesseling P, Wurdinger T, de Vries HE. van Tellingen O, et al. Drug Resist Updat. 2015 Mar;19:1-12. doi: 10.1016/j.drup.2015.02.002. Epub 2015 Mar 6. Drug Resist Updat. 2015. PMID: 25791797 Review.
Unfortunately, glioblastoma multiforme (GBM) patients have not yet profited as although numerous experimental drugs have been tested in clinical trials, all failed miserably. This grim prognosis for GBM is at least partly due to the lack of successful drug delivery across …
Unfortunately, glioblastoma multiforme (GBM) patients have not yet profited as although numerous experimental drugs have been tested in clin …
Cerebral Small Vessel Disease Progression and the Risk of Dementia: A 14-Year Follow-Up Study.
Jacob MA, Cai M, van de Donk V, Bergkamp M, Marques J, Norris DG, Kessels RPC, Claassen JAHR, Duering M, Tuladhar AM, Leeuw FE. Jacob MA, et al. Am J Psychiatry. 2023 Jul 1;180(7):508-518. doi: 10.1176/appi.ajp.20220380. Epub 2023 Apr 19. Am J Psychiatry. 2023. PMID: 37073486
OBJECTIVE: Cerebral small vessel disease (SVD) is considered the most important vascular contributor to cognitive decline and dementia, although a causal relation between its MRI markers and dementia still needs to be established. ...WMH progression predic …
OBJECTIVE: Cerebral small vessel disease (SVD) is considered the most important vascular contributor to cognitive decli …
Incident cerebral lacunes: A review.
Ling Y, Chabriat H. Ling Y, et al. J Cereb Blood Flow Metab. 2020 May;40(5):909-921. doi: 10.1177/0271678X20908361. Epub 2020 Mar 3. J Cereb Blood Flow Metab. 2020. PMID: 32126874 Free PMC article. Review.
Lacunes on magnetic resonance imaging (MRI) are considered as a key hallmark for evaluating the progression and severity of cerebral small vessel diseases. We aimed to review the MRI diagnostic criteria, frequency, predictors and clinical impact of inc …
Lacunes on magnetic resonance imaging (MRI) are considered as a key hallmark for evaluating the progression and severity of cerebral smal …
Lacunar infarct.
Lastilla M. Lastilla M. Clin Exp Hypertens. 2006 Apr-May;28(3-4):205-15. doi: 10.1080/10641960600549082. Clin Exp Hypertens. 2006. PMID: 16833026 Review.
The term lacuna, or cerebral infarct, refers to a well-defined, subcortical ischemic lesion at the level of a single perforating artery, determined by primary disease of the latter. The radiological image is that of a small, deep infarct. ...Hemodynamic disorders al …
The term lacuna, or cerebral infarct, refers to a well-defined, subcortical ischemic lesion at the level of a single perforating artery, det …
Vascular Aging and Disease of the Small Vessels.
Rizzoni D, Rizzoni M, Nardin M, Chiarini G, Agabiti-Rosei C, Aggiusti C, Paini A, Salvetti M, Muiesan ML. Rizzoni D, et al. High Blood Press Cardiovasc Prev. 2019 Jun;26(3):183-189. doi: 10.1007/s40292-019-00320-w. Epub 2019 May 29. High Blood Press Cardiovasc Prev. 2019. PMID: 31144248 Review.
The relationship between large stiffening artery and microvascular disease may be bidirectional, since wave reflection from microvascular sites could increase systolic blood pressure and pulse pressure, while transmission of increased arterial pulsatility to microve …
The relationship between large stiffening artery and microvascular disease may be bidirectional, since wave reflection from microvasc …
Cystatin C in Cerebrovascular Disorders.
Zhang Y, Sun L. Zhang Y, et al. Curr Neurovasc Res. 2017;14(4):406-414. doi: 10.2174/1567202614666171116102504. Curr Neurovasc Res. 2017. PMID: 29149834 Review.
Cystatin C (CysC), a cysteine protease inhibitor, has been widely proven to be a highly sensitive biomarker to predict the kidney function. The similarity of the renal and cerebral small vessels has awakened a surge of studies suggesting that CysC plays a key …
Cystatin C (CysC), a cysteine protease inhibitor, has been widely proven to be a highly sensitive biomarker to predict the kidney fun …
Update on cerebral small vessel disease: a dynamic whole-brain disease.
Shi Y, Wardlaw JM. Shi Y, et al. Stroke Vasc Neurol. 2016 Oct 25;1(3):83-92. doi: 10.1136/svn-2016-000035. eCollection 2016 Sep. Stroke Vasc Neurol. 2016. PMID: 28959468 Free PMC article. Review.
Cerebral small vessel disease (CSVD) is a very common neurological disease in older people. ...Increasing evidence suggests that new studies should consider drugs that target endothelium and blood-brain barrier to prevent and treat CSVD. …
Cerebral small vessel disease (CSVD) is a very common neurological disease in older people. ...Increasing eviden …
Pathomechanisms of Vascular Depression in Older Adults.
Jellinger KA. Jellinger KA. Int J Mol Sci. 2021 Dec 28;23(1):308. doi: 10.3390/ijms23010308. Int J Mol Sci. 2021. PMID: 35008732 Free PMC article. Review.
Depression in older individuals is a common complex mood disorder with high comorbidity of both psychiatric and physical diseases, associated with high disability, cognitive decline, and increased mortality The factors predicting the risk of late-life depression (LL …
Depression in older individuals is a common complex mood disorder with high comorbidity of both psychiatric and physical diseases, as …
2,699 results