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Quoted phrase not found in phrase index: "Calcineurin Inhibitor - Induced Nephropathy"
Page 1
Membranous nephropathy.
Ronco P, Beck L, Debiec H, Fervenza FC, Hou FF, Jha V, Sethi S, Tong A, Vivarelli M, Wetzels J. Ronco P, et al. Nat Rev Dis Primers. 2021 Sep 30;7(1):69. doi: 10.1038/s41572-021-00303-z. Nat Rev Dis Primers. 2021. PMID: 34593809 Review.
In those at high risk of progression, immunosuppressive therapy with cyclophosphamide plus corticosteroids has substantially reduced the need for kidney replacement therapy. Owing to carcinogenic risk, other treatments (calcineurin inhibitors and CD20-targete …
In those at high risk of progression, immunosuppressive therapy with cyclophosphamide plus corticosteroids has substantially reduced the nee …
Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis.
Barrera-Chimal J, Girerd S, Jaisser F. Barrera-Chimal J, et al. Kidney Int. 2019 Aug;96(2):302-319. doi: 10.1016/j.kint.2019.02.030. Epub 2019 Mar 13. Kidney Int. 2019. PMID: 31133455 Free article. Review.
The ultimate therapeutic option for CKD is kidney transplantation. However, the use of drugs that target specific pathways to delay or halt CKD progression, such as angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and sodium-glucose co-transp …
The ultimate therapeutic option for CKD is kidney transplantation. However, the use of drugs that target specific pathways to delay o …
Cellular aspects of the pathogenesis of lupus nephritis.
Chang A, Clark MR, Ko K. Chang A, et al. Curr Opin Rheumatol. 2021 Mar 1;33(2):197-204. doi: 10.1097/BOR.0000000000000777. Curr Opin Rheumatol. 2021. PMID: 33394604 Free PMC article. Review.
In combination with mycophenolate mofetil, a B-cell-targeted therapy (belimumab) and a calcineurin inhibitor (voclosporin) have shown efficacy in recent lupus nephritis trials. ...SUMMARY: Better understanding of the pathogenesis of TII will identify novel therapeut …
In combination with mycophenolate mofetil, a B-cell-targeted therapy (belimumab) and a calcineurin inhibitor (voclosporin) hav …
The STARMEN trial indicates that alternating treatment with corticosteroids and cyclophosphamide is superior to sequential treatment with tacrolimus and rituximab in primary membranous nephropathy.
Fernández-Juárez G, Rojas-Rivera J, Logt AV, Justino J, Sevillano A, Caravaca-Fontán F, Ávila A, Rabasco C, Cabello V, Varela A, Díez M, Martín-Reyes G, Diezhandino MG, Quintana LF, Agraz I, Gómez-Martino JR, Cao M, Rodríguez-Moreno A, Rivas B, Galeano C, Bonet J, Romera A, Shabaka A, Plaisier E, Espinosa M, Egido J, Segarra A, Lambeau G, Ronco P, Wetzels J, Praga M; STARMEN Investigators. Fernández-Juárez G, et al. Kidney Int. 2021 Apr;99(4):986-998. doi: 10.1016/j.kint.2020.10.014. Epub 2020 Nov 7. Kidney Int. 2021. PMID: 33166580 Free article. Clinical Trial.
A cyclical corticosteroid-cyclophosphamide regimen is recommended for patients with primary membranous nephropathy at high risk of progression. We hypothesized that sequential therapy with tacrolimus and rituximab is superior to cyclical alternating treatment with corticos …
A cyclical corticosteroid-cyclophosphamide regimen is recommended for patients with primary membranous nephropathy at high risk of pr …
B cell suppression in primary glomerular disease.
Rood IM, Hofstra JM, Deegens JK, Wetzels JF. Rood IM, et al. Adv Chronic Kidney Dis. 2014 Mar;21(2):166-81. doi: 10.1053/j.ackd.2014.01.005. Adv Chronic Kidney Dis. 2014. PMID: 24602466 Review.
For many years prednisone, alkylating agents, and calcineurin inhibitors have been the standard of therapy for these patients. ...In contrast, response is limited in patients with steroid-resistant nephrotic syndrome. Rituximab also induces remissions in pati …
For many years prednisone, alkylating agents, and calcineurin inhibitors have been the standard of therapy for these patients. …
Calcineurin and Systemic Lupus Erythematosus: The Rationale for Using Calcineurin Inhibitors in the Treatment of Lupus Nephritis.
Rafael-Vidal C, Altabás I, Pérez N, Mourino Rodríguez C, Pego-Reigosa JM, Garcia S. Rafael-Vidal C, et al. Int J Mol Sci. 2021 Jan 27;22(3):1263. doi: 10.3390/ijms22031263. Int J Mol Sci. 2021. PMID: 33514066 Free PMC article. Review.
Moreover, calcineurin is also involved in the alterations of the podocyte phenotype, which contribute to proteinuria and kidney damage observed in LN patients. ...Here, we review the role of calcineurin in SLE and the latest findings about calcineur …
Moreover, calcineurin is also involved in the alterations of the podocyte phenotype, which contribute to proteinuria and kidney …
Cancers after renal transplantation.
Wong G, Chapman JR. Wong G, et al. Transplant Rev (Orlando). 2008 Apr;22(2):141-9. doi: 10.1016/j.trre.2007.12.004. Transplant Rev (Orlando). 2008. PMID: 18631867 Review.
For patients with end-stage kidney failure, kidney transplantation improves both their quality of life and overall life expectancy compared with dialysis, but it is not without adverse effects. ...Uncertainties exist as to how modern immunosuppressive agents impact …
For patients with end-stage kidney failure, kidney transplantation improves both their quality of life and overall life expect …
The pharmacogenetics of calcineurin inhibitor-related nephrotoxicity.
Hesselink DA, Bouamar R, van Gelder T. Hesselink DA, et al. Ther Drug Monit. 2010 Aug;32(4):387-93. doi: 10.1097/FTD.0b013e3181e44244. Ther Drug Monit. 2010. PMID: 20571464 Review.
Chronic calcineurin inhibitor (CNI)-induced nephrotoxicity is associated with prolonged use of cyclosporine and tacrolimus and has been observed after all types of transplantation, as well as during treatment of autoimmune disease. ...Increasing eviden …
Chronic calcineurin inhibitor (CNI)-induced nephrotoxicity is associated with prolonged use of cyclosporine and tacroli …
Mineralocorticoid receptor antagonists in kidney transplantation: time to consider?
Girerd S, Jaisser F. Girerd S, et al. Nephrol Dial Transplant. 2018 Dec 1;33(12):2080-2091. doi: 10.1093/ndt/gfy065. Nephrol Dial Transplant. 2018. PMID: 29672718 Review.
Preclinical studies suggest that MRAs may prevent ischaemia/reperfusion-related lesions in addition to having a protective effect in preventing calcineurin inhibitor-induced nephrotoxicity. Clinical data also support the anti-proteinuric effect of MRAs in chr …
Preclinical studies suggest that MRAs may prevent ischaemia/reperfusion-related lesions in addition to having a protective effect in prevent …
Risk factors for calcineurin inhibitor nephrotoxicity after renal transplantation: a systematic review and meta-analysis.
Xia T, Zhu S, Wen Y, Gao S, Li M, Tao X, Zhang F, Chen W. Xia T, et al. Drug Des Devel Ther. 2018 Feb 28;12:417-428. doi: 10.2147/DDDT.S149340. eCollection 2018. Drug Des Devel Ther. 2018. PMID: 29535503 Free PMC article. Review.
BACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is the major concern for long-term allograft survival despite its predominant role in current immunosuppressive regime after renal transplantation. ...CNI nephrotoxicity was primarily indicated with protoco …
BACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is the major concern for long-term allograft survival despite its …
430 results