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Page 1
Calcineurin nephrotoxicity.
Williams D, Haragsim L. Williams D, et al. Adv Chronic Kidney Dis. 2006 Jan;13(1):47-55. doi: 10.1053/j.ackd.2005.11.001. Adv Chronic Kidney Dis. 2006. PMID: 16412970 Review.
Chronic allograft dysfunction is the major hindrance to long-term graft survival and many components contribute to this entity, both immunologic and nonimmunologic. Chronic calcineurin nephrotoxicity is a major factor in chronic allograft dysfunction. This review wi …
Chronic allograft dysfunction is the major hindrance to long-term graft survival and many components contribute to this entity, both immunol …
Safety of mTOR inhibitors in adult solid organ transplantation.
Ventura-Aguiar P, Campistol JM, Diekmann F. Ventura-Aguiar P, et al. Expert Opin Drug Saf. 2016;15(3):303-19. doi: 10.1517/14740338.2016.1132698. Epub 2016 Jan 28. Expert Opin Drug Saf. 2016. PMID: 26667069 Review.
In the liver, conversion 4 weeks post-transplantation may reduce long-term chronic kidney disease secondary to calcineurin nephrotoxicity, without increasing hepatic artery/portal vein thrombosis....
In the liver, conversion 4 weeks post-transplantation may reduce long-term chronic kidney disease secondary to calcineurin nephrot
The pathobiology of chronic allograft nephropathy: immune-mediated damage and accelerated aging.
Joosten SA, van Kooten C, Sijpkens YW, de Fijter JW, Paul LC. Joosten SA, et al. Kidney Int. 2004 May;65(5):1556-9. doi: 10.1111/j.1523-1755.2004.05410.x. Kidney Int. 2004. PMID: 15086891 Free article. Review.
Chronic allograft nephropathy includes chronic calcineurin nephrotoxicity, recurrent and de novo glomerulonephritis and a group of disorders with graft dysfunction of unknown etiology designated chronic rejection. ...
Chronic allograft nephropathy includes chronic calcineurin nephrotoxicity, recurrent and de novo glomerulonephritis and a grou …
Alemtuzumab and sirolimus in renal transplantation: six-year results of a single-arm prospective pilot study.
Sutherland AI, Akhtar MZ, Zilvetti M, Brockmann J, Ruse S, Fuggle SV, Sinha S, Harden P, Friend PJ. Sutherland AI, et al. Am J Transplant. 2014 Mar;14(3):677-84. doi: 10.1111/ajt.12572. Am J Transplant. 2014. PMID: 24612687 Free article.
mTOR inhibitors avoid calcineurin nephrotoxicity, but sirolimus de novo is associated with unacceptable side effects and higher rejection rates. ...
mTOR inhibitors avoid calcineurin nephrotoxicity, but sirolimus de novo is associated with unacceptable side effects and highe …
Renal histopathological lesions after orthotopic liver transplantation (OLT).
Pillebout E, Nochy D, Hill G, Conti F, Antoine C, Calmus Y, Glotz D. Pillebout E, et al. Am J Transplant. 2005 May;5(5):1120-9. doi: 10.1111/j.1600-6143.2005.00852.x. Am J Transplant. 2005. PMID: 15816895 Free article.
Thus, CRF in OLT recipients is more complex than originally thought and should not be classified as anti-calcineurin nephrotoxicity without further investigations, including renal histology. ...
Thus, CRF in OLT recipients is more complex than originally thought and should not be classified as anti-calcineurin nephrotoxicit
Sodium thiosulfate treatment for calcific uremic arteriolopathy in children and young adults.
Araya CE, Fennell RS, Neiberger RE, Dharnidharka VR. Araya CE, et al. Clin J Am Soc Nephrol. 2006 Nov;1(6):1161-6. doi: 10.2215/CJN.01520506. Epub 2006 Aug 30. Clin J Am Soc Nephrol. 2006. PMID: 17699342
The patients were between 12 and 21 yr of age; two were male; and primary diagnoses were obstructive uropathy, renal dysplasia, and calcineurin nephrotoxicity. Time from ESRD to CUA diagnosis was 1, 9, and 20 yr. ...
The patients were between 12 and 21 yr of age; two were male; and primary diagnoses were obstructive uropathy, renal dysplasia, and calci
Histological findings of early graft biopsies in old donor renal transplant patients receiving induction therapy.
Gavela E, Pallardó LM, Sancho A, Avilla A, Beltrán S, Roselló E, Pérez ML, García F. Gavela E, et al. Transplant Proc. 2009 Jul-Aug;41(6):2099-101. doi: 10.1016/j.transproceed.2009.06.058. Transplant Proc. 2009. PMID: 19715842
Histological evaluation showed: acute tabular necrosis in 7 (78%) Thymoglobulin patients versus 14 (45%) basiliximab patients, with calcineurin nephrotoxicity in 2 (22%) and 1 (3.2%), respectively. An acute rejection episode was not diagnosed in the Thymoglobulin gr …
Histological evaluation showed: acute tabular necrosis in 7 (78%) Thymoglobulin patients versus 14 (45%) basiliximab patients, with calci