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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1975 1
1976 1
1977 1
1978 3
1979 3
1980 2
1981 3
1982 4
1983 5
1984 5
1985 6
1986 5
1987 4
1988 12
1989 10
1990 9
1991 13
1992 15
1993 14
1994 18
1995 24
1996 24
1997 22
1998 25
1999 25
2000 28
2001 25
2002 44
2003 39
2004 31
2005 32
2006 46
2007 39
2008 35
2009 47
2010 54
2011 70
2012 86
2013 75
2014 99
2015 88
2016 98
2017 104
2018 119
2019 137
2020 137
2021 129
2022 118
2023 122
2024 49

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1,848 results

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Quoted phrase not found in phrase index: "Cancer, variable types"
Page 1
Mitochondrial related genome-wide Mendelian randomization identifies putatively causal genes for multiple cancer types.
Li Y, Sundquist K, Zhang N, Wang X, Sundquist J, Memon AA. Li Y, et al. EBioMedicine. 2023 Feb;88:104432. doi: 10.1016/j.ebiom.2022.104432. Epub 2023 Jan 10. EBioMedicine. 2023. PMID: 36634566 Free PMC article.
BACKGROUND: Mitochondrial dysfunction is a hallmark of cancer. However, it is unclear whether it is a cause of cancer. This two-sample Mendelian randomization (MR) analyses, uses genetic instruments to proxy the exposure of mitochondrial dysfunction and ca …
BACKGROUND: Mitochondrial dysfunction is a hallmark of cancer. However, it is unclear whether it is a cause of cancer. This tw …
Chronic lymphocytic leukemia: 2022 update on diagnostic and therapeutic procedures.
Hallek M, Al-Sawaf O. Hallek M, et al. Am J Hematol. 2021 Dec 1;96(12):1679-1705. doi: 10.1002/ajh.26367. Am J Hematol. 2021. PMID: 34625994 Free article. Review.
DISEASE OVERVIEW: Chronic lymphocytic leukemia (CLL) is one of the most frequent types of leukemia. It typically occurs in elderly patients and has a highly variable clinical course. ...The CLL international prognostic index integrates genetic, biological, an …
DISEASE OVERVIEW: Chronic lymphocytic leukemia (CLL) is one of the most frequent types of leukemia. It typically occurs in elderly pa …
Proton therapy - Present and future.
Mohan R, Grosshans D. Mohan R, et al. Adv Drug Deliv Rev. 2017 Jan 15;109:26-44. doi: 10.1016/j.addr.2016.11.006. Epub 2016 Dec 3. Adv Drug Deliv Rev. 2017. PMID: 27919760 Free PMC article. Review.
The latter technique can be used to treat patients with optimized intensity modulated proton therapy (IMPT), the most powerful proton modality. Despite the high potential of proton therapy, the clinical evidence supporting the broad use of protons is mixed. It is generally …
The latter technique can be used to treat patients with optimized intensity modulated proton therapy (IMPT), the most powerful proton modali …
Selenium for preventing cancer.
Vinceti M, Filippini T, Del Giovane C, Dennert G, Zwahlen M, Brinkman M, Zeegers MP, Horneber M, D'Amico R, Crespi CM. Vinceti M, et al. Cochrane Database Syst Rev. 2018 Jan 29;1(1):CD005195. doi: 10.1002/14651858.CD005195.pub4. Cochrane Database Syst Rev. 2018. PMID: 29376219 Free PMC article. Review.
Summary RRs for site-specific cancers showed limited changes compared with estimates from high-quality studies alone, except for liver cancer, for which results were reversed.In the largest trial, the Selenium and Vitamin E Cancer Trial, seleniu …
Summary RRs for site-specific cancers showed limited changes compared with estimates from high-quality studies alone, except for live …
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
Zingg D, Bhin J, Yemelyanenko J, Kas SM, Rolfs F, Lutz C, Lee JK, Klarenbeek S, Silverman IM, Annunziato S, Chan CS, Piersma SR, Eijkman T, Badoux M, Gogola E, Siteur B, Sprengers J, de Klein B, de Goeij-de Haas RR, Riedlinger GM, Ke H, Madison R, Drenth AP, van der Burg E, Schut E, Henneman L, van Miltenburg MH, Proost N, Zhen H, Wientjens E, de Bruijn R, de Ruiter JR, Boon U, de Korte-Grimmerink R, van Gerwen B, Féliz L, Abou-Alfa GK, Ross JS, van de Ven M, Rottenberg S, Cuppen E, Chessex AV, Ali SM, Burn TC, Jimenez CR, Ganesan S, Wessels LFA, Jonkers J. Zingg D, et al. Nature. 2022 Aug;608(7923):609-617. doi: 10.1038/s41586-022-05066-5. Epub 2022 Aug 10. Nature. 2022. PMID: 35948633 Free PMC article. Clinical Trial.
Somatic hotspot mutations and structural amplifications and fusions that affect fibroblast growth factor receptor 2 (encoded by FGFR2) occur in multiple types of cancer(1). However, clinical responses to FGFR inhibitors have remained variable(1-9), emp …
Somatic hotspot mutations and structural amplifications and fusions that affect fibroblast growth factor receptor 2 (encoded by FGFR2) occur …
Genetically Predicted Circulating Levels of Cytokines and the Risk of Cancer.
Song J, Li A, Qian Y, Liu B, Lv L, Ye D, Sun X, Mao Y. Song J, et al. Front Immunol. 2022 Jul 5;13:886144. doi: 10.3389/fimmu.2022.886144. eCollection 2022. Front Immunol. 2022. PMID: 35865545 Free PMC article.
BACKGROUND: Inflammation plays a pivotal role in the pathogenesis of cancer. Though previous studies have reported a link between several inflammatory biomarkers and risk of certain types of cancer, there is a lack of systematic investigation. Therefore, we a …
BACKGROUND: Inflammation plays a pivotal role in the pathogenesis of cancer. Though previous studies have reported a link between sev …
Assessment of causal effects of visceral adipose tissue on risk of cancers: a Mendelian randomization study.
Lu Y, Tang H, Huang P, Wang J, Deng P, Li Y, Zheng J, Weng L. Lu Y, et al. Int J Epidemiol. 2022 Aug 10;51(4):1204-1218. doi: 10.1093/ije/dyac025. Int J Epidemiol. 2022. PMID: 35218345 Free PMC article.
METHODS: We conducted two-sample Mendelian randomization (MR) analysis to assess the causal effects of visceral adipose tissue (VAT) on six common cancers. ...There was no evidence for a causal effect of VAT on the risk of other types of cancer. CONCLU …
METHODS: We conducted two-sample Mendelian randomization (MR) analysis to assess the causal effects of visceral adipose tissue (VAT) …
Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study.
Vithayathil M, Carter P, Kar S, Mason AM, Burgess S, Larsson SC. Vithayathil M, et al. PLoS Med. 2021 Jul 29;18(7):e1003706. doi: 10.1371/journal.pmed.1003706. eCollection 2021 Jul. PLoS Med. 2021. PMID: 34324486 Free PMC article.

For sex-specific cancers, genetically predicted elevated BMI was associated with an increased risk of uterine cancer (OR 1.10, 95% CI 1.05-1.15; p < 0.001) and with a lower risk of prostate cancer (OR 0.97, 95% CI 0.94-0.99; p = 0.009). ...The main limitat

…
For sex-specific cancers, genetically predicted elevated BMI was associated with an increased risk of uterine cancer (OR 1.10, …
Risk-reducing mastectomy for the prevention of primary breast cancer.
Carbine NE, Lostumbo L, Wallace J, Ko H. Carbine NE, et al. Cochrane Database Syst Rev. 2018 Apr 5;4(4):CD002748. doi: 10.1002/14651858.CD002748.pub4. Cochrane Database Syst Rev. 2018. PMID: 29620792 Free PMC article. Review.
SEARCH METHODS: For this Review update, we searched Cochrane Breast Cancer's Specialized Register, MEDLINE, Embase and the WHO International Clinical Trials Registry Platform (ICTRP) on 9 July 2016. ...SELECTION CRITERIA: Participants included women at risk f …
SEARCH METHODS: For this Review update, we searched Cochrane Breast Cancer's Specialized Register, MEDLINE, Embase and the WHO …
Mitochondrial DNA copy number and cancer risks: A comprehensive Mendelian randomization analysis.
Cai X, Liang C, Zhang M, Dong Z, Weng Y, Yu W. Cai X, et al. Int J Cancer. 2024 Apr 15;154(8):1504-1513. doi: 10.1002/ijc.34833. Epub 2023 Dec 27. Int J Cancer. 2024. PMID: 38151753
Mitochondrial DNA plays a critical role in the pathophysiology of cancer. However, the associations between mitochondrial DNA copy number (mtDNA-CN) and cancer risk are controversial. Mendelian randomization (MR) analyses were performed using three independen …
Mitochondrial DNA plays a critical role in the pathophysiology of cancer. However, the associations between mitochondrial DNA copy nu …
1,848 results