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MiR-22-3p Regulates Cell Proliferation and Inhibits Cell Apoptosis through Targeting the eIF4EBP3 Gene in Human Cervical Squamous Carcinoma Cells.
Lv KT, Liu Z, Feng J, Zhao W, Hao T, Ding WY, Chu JP, Gao LJ. Lv KT, et al. Int J Med Sci. 2018 Jan 1;15(2):142-152. doi: 10.7150/ijms.21645. eCollection 2018. Int J Med Sci. 2018. PMID: 29333098 Free PMC article.
Results: Among the aberrantly expressed miRNAs, miR-22-3p was significantly differentially expressed in cervical cancer tissues and was highly associated with cervical cancer cell growth regulation. In addition, bioinformatic predictions and exp …
Results: Among the aberrantly expressed miRNAs, miR-22-3p was significantly differentially expressed in cervical cancer tissues and was high …
Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.
Börnigen D, Tyekucheva S, Wang X, Rider JR, Lee GS, Mucci LA, Sweeney C, Huttenhower C. Börnigen D, et al. PLoS Comput Biol. 2016 Apr 14;12(4):e1004820. doi: 10.1371/journal.pcbi.1004820. eCollection 2016 Apr. PLoS Comput Biol. 2016. PMID: 27078000 Free PMC article.
We identified novel roles for ATF3, CXCL2, DUSP5, JUNB, NEDD9, SELE, TRIB1, and ZFP36 in this pathway, in addition to new mechanistic interactions between these genes and 10 known NFkappaB pathway members. A newly predicted interaction between NEDD9 and ZFP36 in particular …
We identified novel roles for ATF3, CXCL2, DUSP5, JUNB, NEDD9, SELE, TRIB1, and ZFP36 in this pathway, in addition to new mechanistic intera …