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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1951 2
1952 8
1953 4
1954 10
1955 6
1956 5
1957 1
1958 2
1959 4
1960 4
1961 7
1962 3
1965 10
1966 20
1967 23
1968 21
1969 24
1970 30
1971 35
1972 51
1973 37
1974 34
1975 40
1976 36
1977 58
1978 62
1979 55
1980 43
1981 49
1982 43
1983 38
1984 44
1985 55
1986 44
1987 45
1988 35
1989 51
1990 51
1991 61
1992 59
1993 98
1994 110
1995 71
1996 88
1997 57
1998 52
1999 43
2000 106
2001 42
2002 57
2003 109
2004 62
2005 71
2006 96
2007 69
2008 51
2009 75
2010 59
2011 66
2012 100
2013 87
2014 56
2015 84
2016 52
2017 38
2018 64
2019 12
2020 0
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Search Results

2,924 results
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Page 1
The Logic of Carotid Body Connectivity to the Brain.
Zera T, et al. Physiology (Bethesda) 2019 - Review. PMID 31165684
The carotid body has emerged as a therapeutic target for cardio-respiratory-metabolic diseases. With the expansive functions of the chemoreflex, we sought mechanisms to explain differential control of individual responses. ...
The carotid body has emerged as a therapeutic target for cardio-respiratory-metabolic diseases. With the expansive functions o …
Carotid body: a metabolic sensor implicated in insulin resistance.
Conde SV, et al. Physiol Genomics 2018 - Review. PMID 29373079
The carotid body is now looked at as a multipurpose sensor for blood gases, blood pH, and several hormones. The matter of glucose sensing by the carotid body has been debated for several years in the literature, and these days there is a consensus that carotid body activity is modified by metabolic factors that contribute to glucose homeostasis. ...Herein, we debate the glucose and insulin sensing capabilities of the carotid body as key early events in the overactivation of the carotid body, which is increasingly recognized as an important feature of metabolic diseases. ...
The carotid body is now looked at as a multipurpose sensor for blood gases, blood pH, and several hormones. The matter of gluc …
Ageing of the carotid body.
Di Giulio C. J Physiol 2018 - Review. PMID 29319194 Free PMC article.
The lowered homeostatic capacity seems to involve the carotid body (CB), whose role is to modulate ventilation and tissue oxygen supply. ...The carotid glomitis is present with aggregates of lymphocytes and fibrosis of the lobules. Type I cells are dehydrated, with a profound vacuolization, a shrinking nucleus, and lipofuscin accumulation. ...
The lowered homeostatic capacity seems to involve the carotid body (CB), whose role is to modulate ventilation and tissue oxyg …
Measurement of Sensory Nerve Activity from the Carotid Body.
Peng YJ and Prabhakar NR. Methods Mol Biol 2018. PMID 29330795
Hypoxia increases sensory nerve activity of the carotid body, which is transmitted to the brainstem neurons triggering reflex stimulation of breathing and blood pressure. Measurement of action potentials from the carotid sinus nerve is a widely used approach for understanding the mechanisms of hypoxic sensing by the carotid body. ...
Hypoxia increases sensory nerve activity of the carotid body, which is transmitted to the brainstem neurons triggering reflex …
Oxygen Sensing by the Carotid Body: Past and Present.
Prabhakar NR and Peng YJ. Adv Exp Med Biol 2017 - Review. PMID 28685420
It is now well established that carotid bodies are sensory organs for monitoring arterial blood oxygen levels and trigger reflexes that are critical for maintaining homeostasis during hypoxemia. This review article provides a brief account of the early studies leading to the discovery of the carotid body as a sensory receptor and addresses current views of O(2) sensing mechanism(s) in the carotid body and their physiological importance....
It is now well established that carotid bodies are sensory organs for monitoring arterial blood oxygen levels and trigger reflexes th …
The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system.
Sobrino V, et al. Cell Mol Life Sci 2019 - Review. PMID 30498994
The carotid body represents the most important peripheral arterial chemoreceptor organ in mammals and informs about hypoxemic situations to the effectors at the brainstem cardiorespiratory centers. To optimize organismal adaptation to maintained hypoxemic situations, the carotid body has evolved containing a niche of adult tissue-specific stem cells with the capacity to differentiate into both neuronal and vascular cell types in response to hypoxia. ...
The carotid body represents the most important peripheral arterial chemoreceptor organ in mammals and informs about hypoxemic …
Carotid body oxygen sensing and adaptation to hypoxia.
López-Barneo J, et al. Pflugers Arch 2016 - Review. PMID 26373853
The carotid body (CB) is the principal arterial chemoreceptor that mediates the hyperventilatory response to hypoxia. Our understanding of CB function and its role in disease mechanisms has progressed considerably in the last decades, particularly in recent years. ...
The carotid body (CB) is the principal arterial chemoreceptor that mediates the hyperventilatory response to hypoxia. Our unde …
Acute oxygen sensing by the carotid body: a rattlebag of molecular mechanisms.
Rakoczy RJ and Wyatt CN. J Physiol 2018 - Review. PMID 29214644 Free PMC article.
The molecular underpinnings of the oxygen sensitivity of the carotid body Type I cells are becoming better defined as research begins to identify potential interactions between previously separate theories. ...The purpose of this brief review is to address five of the current oxygen sensing hypotheses: the lactate-Olfr 78 hypothesis of oxygen chemotransduction; the role mitochondrial ATP and metabolism may have in chemotransduction; the AMP-activated protein kinase hypothesis and its current role in oxygen sensing by the carotid body; reactive oxygen species as key transducers in the oxygen sensing cascade; and the mechanisms by which H(2) S, reactive oxygen species and haem oxygenase may integrate to provide a rapid oxygen sensing transduction system. ...
The molecular underpinnings of the oxygen sensitivity of the carotid body Type I cells are becoming better defined as research …
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