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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1978 1
1979 1
1986 1
1994 1
1997 2
1998 1
1999 1
2000 6
2001 1
2002 6
2003 10
2004 6
2005 11
2006 10
2007 15
2008 16
2009 15
2010 12
2011 14
2012 11
2013 15
2014 13
2015 29
2016 30
2017 25
2018 15
2019 16
2020 18
2021 14
2022 16
2023 14
2024 5

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301 results

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Page 1
Diagnosis, Monitoring, and Treatment of Systemic Lupus Erythematosus: A Systematic Review of Clinical Practice Guidelines.
Tunnicliffe DJ, Singh-Grewal D, Kim S, Craig JC, Tong A. Tunnicliffe DJ, et al. Arthritis Care Res (Hoboken). 2015 Oct;67(10):1440-52. doi: 10.1002/acr.22591. Arthritis Care Res (Hoboken). 2015. PMID: 25778500 Free article. Review.
The methodological quality of the guidelines was variable, with the overall mean AGREE II scores ranging from 31% to 75%, out of a maximum 100%. Scores were consistently low for applicability, with only 1 guideline scoring above 50%. ...
The methodological quality of the guidelines was variable, with the overall mean AGREE II scores ranging from 31% to 75%, out of a ma …
Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus.
Moore E, Huang MW, Putterman C. Moore E, et al. Curr Opin Rheumatol. 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. Curr Opin Rheumatol. 2020. PMID: 31895125 Free PMC article. Review.
Among such autoantibodies, anti-NR2 and anti-ribosomal P autoantibodies also have a pathogenic role, although newer studies demonstrate that blood-brain barrier damage may not always be required as previously believed. These and other observations, together with new eviden …
Among such autoantibodies, anti-NR2 and anti-ribosomal P autoantibodies also have a pathogenic role, although newer studies demonstrate that …
Management of inflammatory neurologic and psychiatric manifestations of systemic lupus erythematosus: A systematic review.
Papachristos DA, Oon S, Hanly JG, Nikpour M. Papachristos DA, et al. Semin Arthritis Rheum. 2021 Feb;51(1):49-71. doi: 10.1016/j.semarthrit.2020.12.004. Epub 2020 Dec 17. Semin Arthritis Rheum. 2021. PMID: 33360230 Review.
METHODS: Medline, Embase, CINHAL and Cochrane CENTRAL were searched from 1990 to end of March 2019 using key words that related to NPSLE and treatment. Included studies comprised clinical trials, observational studies or case series with 5 patients and sufficient data rela …
METHODS: Medline, Embase, CINHAL and Cochrane CENTRAL were searched from 1990 to end of March 2019 using key words that related to NPSLE and …
Microglia activation in the presence of intact blood-brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus.
Nikolopoulos D, Manolakou T, Polissidis A, Filia A, Bertsias G, Koutmani Y, Boumpas DT. Nikolopoulos D, et al. Ann Rheum Dis. 2023 May;82(5):646-657. doi: 10.1136/ard-2022-223506. Epub 2023 Mar 10. Ann Rheum Dis. 2023. PMID: 36898766 Free PMC article.
During the nephritic stage, BBB becomes disrupted which facilitates immune components of peripheral blood, particularly B-cells, to penetrate into the hippocampus further augmenting inflammation with locally increased levels of IL-6, IL-12, IL-18 and IL-23. Of note, an interferon …
During the nephritic stage, BBB becomes disrupted which facilitates immune components of peripheral blood, particularly B-cells, to penetrat …
Corticosteroids in Lupus Nephritis and Central Nervous System Lupus.
Kamen DL, Zollars ES. Kamen DL, et al. Rheum Dis Clin North Am. 2016 Feb;42(1):63-73, viii. doi: 10.1016/j.rdc.2015.08.008. Epub 2015 Oct 24. Rheum Dis Clin North Am. 2016. PMID: 26611551 Review.
The dose and duration of corticosteroids required for control of lupus nephritis and CNS lupus have never been tested in a randomized trial design, so current recommendations are based on observation and expert opinion. As more targeted individualized therapeutic approache …
The dose and duration of corticosteroids required for control of lupus nephritis and CNS lupus have never been tested in a randomized trial …
Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus.
Cocco C, Manca E, Corda G, Angioni MM, Noli B, Congia M, Loy F, Isola M, Chessa E, Floris A, Lorefice L, Saba L, Mathieu A, Ferri GL, Cauli A, Piga M. Cocco C, et al. Front Immunol. 2023 Jun 13;14:1157149. doi: 10.3389/fimmu.2023.1157149. eCollection 2023. Front Immunol. 2023. PMID: 37383228 Free PMC article.
RESULTS: We enrolled 209 subjects, including patients affected by SLE (n=69), NPSLE (n=36), Multiple Sclerosis (MS, n=22), and 82 age- and gender-matched healthy donors (HD). Autoantibody reactivity by IF was observed in almost the entire rat brain (cortex, hippocampus, an …
RESULTS: We enrolled 209 subjects, including patients affected by SLE (n=69), NPSLE (n=36), Multiple Sclerosis (MS, n=22), and 82 age- and g …
The management of neuropsychiatric lupus in the 21st century: still so many unmet needs?
Govoni M, Hanly JG. Govoni M, et al. Rheumatology (Oxford). 2020 Dec 5;59(Suppl5):v52-v62. doi: 10.1093/rheumatology/keaa404. Rheumatology (Oxford). 2020. PMID: 33280014 Free PMC article. Review.
There is a dearth of controlled clinical trials to guide management, but therapeutic options include symptomatic, antithrombotic and immunosuppressive agents that are supported by observational cohort studies. Our objective was to review what is currently known about NPSLE …
There is a dearth of controlled clinical trials to guide management, but therapeutic options include symptomatic, antithrombotic and immunos …
Neuropsychiatric Systemic Lupus Erythematosus in Older Adults: Diagnosis and Management.
Tayer-Shifman OE, Bingham KS, Touma Z. Tayer-Shifman OE, et al. Drugs Aging. 2022 Feb;39(2):129-142. doi: 10.1007/s40266-021-00911-0. Epub 2021 Dec 16. Drugs Aging. 2022. PMID: 34913146 Review.
Neuropsychiatric systemic lupus erythematosus (NPSLE) includes the neurologic syndromes of the central, peripheral and autonomic nervous system and the psychiatric syndromes observed in patients with SLE. Neuropsychiatric systemic lupus erythematosus events may present as …
Neuropsychiatric systemic lupus erythematosus (NPSLE) includes the neurologic syndromes of the central, peripheral and autonomic nervous sys …
Neuropsychiatric lupus in Malaysian children: clinical characteristics, imaging features and 12-month outcomes.
Lim SC, Md-Yusof YL, Johari B, Abdul-Kadir RF, Tang SP. Lim SC, et al. Turk J Pediatr. 2021;63(5):743-751. doi: 10.24953/turkjped.2021.05.002. Turk J Pediatr. 2021. PMID: 34738356 Free article.
Twenty-three patients had single episodes of NPSLE and five patients had two distinct episodes each. The mean disease activity score (SLEDAI- 2K) was 24.911.8 at presentation with 81.8% having high disease activity (score > 12). ...
Twenty-three patients had single episodes of NPSLE and five patients had two distinct episodes each. The mean disease activity score …
Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers.
Jeltsch-David H, Muller S. Jeltsch-David H, et al. Nat Rev Neurol. 2014 Oct;10(10):579-96. doi: 10.1038/nrneurol.2014.148. Epub 2014 Sep 9. Nat Rev Neurol. 2014. PMID: 25201240 Review.
Thus, efforts to define biomarkers of NPSLE are needed to improve prediction of disease outcomes and guide treatment. In this article, we review the manifestation and pathogenesis of NPSLE, focusing on the features that might aid identification of potential biomarkers....
Thus, efforts to define biomarkers of NPSLE are needed to improve prediction of disease outcomes and guide treatment. In this article …
301 results