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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1978 1
1980 1
1982 2
1985 1
1987 1
1988 1
1989 1
1992 1
1993 1
1994 2
1997 3
1998 2
1999 1
2000 3
2001 4
2002 8
2003 19
2004 5
2005 8
2006 9
2007 15
2008 13
2009 15
2010 10
2011 10
2012 12
2013 18
2014 14
2015 20
2016 19
2017 17
2018 13
2019 10
2020 12
2021 10
2022 11
2023 6
2024 1

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262 results

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Page 1
Update οn the diagnosis and management of systemic lupus erythematosus.
Fanouriakis A, Tziolos N, Bertsias G, Boumpas DT. Fanouriakis A, et al. Ann Rheum Dis. 2021 Jan;80(1):14-25. doi: 10.1136/annrheumdis-2020-218272. Epub 2020 Oct 13. Ann Rheum Dis. 2021. PMID: 33051219 Free article. Review.
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus erythematosus (SLE). ...There is increased recognition of milder cases at presentation, but almost half of them progress overtime to more severe disease. Approximately 70% of pati …
Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus erythematosus (SLE). ...There is increa …
Neuropsychiatric lupus: new mechanistic insights and future treatment directions.
Schwartz N, Stock AD, Putterman C. Schwartz N, et al. Nat Rev Rheumatol. 2019 Mar;15(3):137-152. doi: 10.1038/s41584-018-0156-8. Nat Rev Rheumatol. 2019. PMID: 30659245 Free PMC article. Review.
The CNS manifestations of SLE are diverse and have a broad spectrum of severity and prognostic implications. Patients with NPSLE typically present with nonspecific symptoms, such as headache and cognitive impairment, but might also experience devastating features, such as …
The CNS manifestations of SLE are diverse and have a broad spectrum of severity and prognostic implications. Patients with NPSLE typi …
Advances in the diagnosis, pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus.
Moore E, Huang MW, Putterman C. Moore E, et al. Curr Opin Rheumatol. 2020 Mar;32(2):152-158. doi: 10.1097/BOR.0000000000000682. Curr Opin Rheumatol. 2020. PMID: 31895125 Free PMC article. Review.
SUMMARY: Neuropsychiatric involvement of SLE includes a variety of symptoms that impact quality of life and patient prognosis. There have been recent advances in improving the diagnosis of NPSLE as well as in dissecting the underlying pathogenesis. ...
SUMMARY: Neuropsychiatric involvement of SLE includes a variety of symptoms that impact quality of life and patient prognosis. There …
Microglia activation in the presence of intact blood-brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus.
Nikolopoulos D, Manolakou T, Polissidis A, Filia A, Bertsias G, Koutmani Y, Boumpas DT. Nikolopoulos D, et al. Ann Rheum Dis. 2023 May;82(5):646-657. doi: 10.1136/ard-2022-223506. Epub 2023 Mar 10. Ann Rheum Dis. 2023. PMID: 36898766 Free PMC article.
Disturbances of the BBB and interferon signature are evident later in the course of the disease....
Disturbances of the BBB and interferon signature are evident later in the course of the disease....
EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs.
Bertsias GK, Ioannidis JP, Aringer M, Bollen E, Bombardieri S, Bruce IN, Cervera R, Dalakas M, Doria A, Hanly JG, Huizinga TW, Isenberg D, Kallenberg C, Piette JC, Schneider M, Scolding N, Smolen J, Stara A, Tassiulas I, Tektonidou M, Tincani A, van Buchem MA, van Vollenhoven R, Ward M, Gordon C, Boumpas DT. Bertsias GK, et al. Ann Rheum Dis. 2010 Dec;69(12):2074-82. doi: 10.1136/ard.2010.130476. Epub 2010 Aug 19. Ann Rheum Dis. 2010. PMID: 20724309
METHODS: The authors compiled questions on prevalence and risk factors, diagnosis and monitoring, therapy and prognosis of NPSLE. A systematic literature search was performed and evidence was categorised based on sample size and study design. ...
METHODS: The authors compiled questions on prevalence and risk factors, diagnosis and monitoring, therapy and prognosis of NPSLE. A s …
Neuropsychiatric lupus erythematosus: Focusing on autoantibodies.
Wang J, Xu J, Yang P. Wang J, et al. J Autoimmun. 2022 Oct;132:102892. doi: 10.1016/j.jaut.2022.102892. Epub 2022 Aug 25. J Autoimmun. 2022. PMID: 36030137 Review.
Patients with systemic lupus erythematosus (SLE) frequently suffer from nervous system complications, termed neuropsychiatric lupus erythematosus (NPLE). NPLE accounts for the poor prognosis of SLE. Correct attribution of NP events to SLE is the primary principle in managi …
Patients with systemic lupus erythematosus (SLE) frequently suffer from nervous system complications, termed neuropsychiatric lupus erythema …
Neuropsychiatric Lupus in clinical practice.
Alessi H, Dutra LA, Braga P Neto, Pedroso JL, Toso FF, Kayser C, Barsottini OG. Alessi H, et al. Arq Neuropsiquiatr. 2016 Dec;74(12):1021-1030. doi: 10.1590/0004-282X20160150. Arq Neuropsiquiatr. 2016. PMID: 27992002 Free article. Review.
As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are associated with impaired quality of life, and high morbidity and mortality rates. ...
As many as 50% of patients with SLE have neurological involvement during the course of their disease. Neurological manifestations are …
Central nervous system involvement in systemic lupus erythematosus: Data from the Spanish Society of Rheumatology Lupus Register (RELESSER).
Magro-Checa C, Ramiro S, Rúa-Figueroa I, Jimenez N, Del Campo-Pérez V, Martinez-Barrio J, Galindo-Izquierdo M, Calvo-Alén J, Uriarte-Isacelaya E, Tomero-Muriel E, Freire-González M, Martínez-Taboada V, Salgado E, Vela P, Mena-Vázquez N, Olivé A, Narváez J, Menor-Almagro R, Santos-Soler G, Hernández-Beriaín JA, Manero-Ruiz J, Aurrecoechea-Aguinaga E, Ibarguengoitia O, Montilla-Morales C, Bonilla-Hernán G, Torrente-Segarra V, Salman-Monte T, Ros-Vilamajo I, García-Villanueva MJ, Moriano-Morales C, Fito-Manteca C, Lozano-Rivas N, Bohórquez C, Pego-Reigosa JM. Magro-Checa C, et al. Semin Arthritis Rheum. 2023 Feb;58:152121. doi: 10.1016/j.semarthrit.2022.152121. Epub 2022 Oct 22. Semin Arthritis Rheum. 2023. PMID: 36375359
Major CNS NP-SLE (HR 1.85, 1.29-2.67) and more specifically CVD (HR 2.17, 1.41-3.33) and organic brain syndrome (HR 2.11, 1.19-3.74) accounted as independent prognostic factors for poor survival. CONCLUSION: The presentation of major CNS NP-SLE during the disease course …
Major CNS NP-SLE (HR 1.85, 1.29-2.67) and more specifically CVD (HR 2.17, 1.41-3.33) and organic brain syndrome (HR 2.11, 1.19-3.74) account …
262 results