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1987 1
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13 results

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Page 1
Neurocognitive and psychosocial outcomes in adult survivors of childhood soft-tissue sarcoma: A report from the St. Jude Lifetime Cohort.
Tonning Olsson I, Brinkman TM, Wang M, Ehrhardt MJ, Banerjee P, Mulrooney DA, Huang IC, Ness KK, Bishop MW, Srivastava D, Robison LL, Hudson MM, Krull KR. Tonning Olsson I, et al. Cancer. 2020 Apr 1;126(7):1576-1584. doi: 10.1002/cncr.32694. Epub 2020 Jan 8. Cancer. 2020. PMID: 31913509 Free PMC article.
BACKGROUND: To the authors' knowledge, few studies to date have examined long-term neurocognitive outcomes in survivors of childhood soft-tissue sarcoma. METHODS: A total of 150 survivors (41% of whom were female with a mean current age of 33 years [SD …
BACKGROUND: To the authors' knowledge, few studies to date have examined long-term neurocognitive outcomes in survivors of childhood …
Cancer in survivors of childhood soft tissue sarcoma and their relatives.
Strong LC, Stine M, Norsted TL. Strong LC, et al. J Natl Cancer Inst. 1987 Dec;79(6):1213-20. J Natl Cancer Inst. 1987. PMID: 3480372
One hundred fifty-nine 3-year survivors of childhood soft tissue sarcoma and their relatives were surveyed to determine the frequency of second malignant neoplasms (SMNs) in patients and cancer in their relatives. ...The findings confirm an association …
One hundred fifty-nine 3-year survivors of childhood soft tissue sarcoma and their relatives were surveyed to de …
Childhood soft tissue sarcoma: a 20-year experience.
Marcus KC, Grier HE, Shamberger RC, Gebhardt MC, Perez-Atayde A, Silver B, Tarbell NJ. Marcus KC, et al. J Pediatr. 1997 Oct;131(4):603-7. doi: 10.1016/s0022-3476(97)70070-2. J Pediatr. 1997. PMID: 9386667
CONCLUSIONS: As with adult soft tissue sarcomas, gross residual disease predicts local failure. Our results suggest that pediatric patients with soft tissue sarcomas treated with surgery and postoperative radiotherapy generally have a favorable overall survival rate....
CONCLUSIONS: As with adult soft tissue sarcomas, gross residual disease predicts local failure. Our results suggest that pediatric pa …
The risk of developing second cancers among survivors of childhood soft tissue sarcoma.
Cohen RJ, Curtis RE, Inskip PD, Fraumeni JF Jr. Cohen RJ, et al. Cancer. 2005 Jun 1;103(11):2391-6. doi: 10.1002/cncr.21040. Cancer. 2005. PMID: 15852362 Free article.
RESULTS: Twenty-seven children developed 28 subsequent primary malignancies, compared with 4.5 expected malignancies based on general population rates (observed-to-expected [O/E] ratio = 6.3 (95% confidence interval [95% CI], 4.2-9.1). The risk of developing a subsequent m …
RESULTS: Twenty-seven children developed 28 subsequent primary malignancies, compared with 4.5 expected malignancies based on general popula …
Segregation analysis of cancer in families of childhood soft-tissue-sarcoma patients.
Lustbader ED, Williams WR, Bondy ML, Strom S, Strong LC. Lustbader ED, et al. Am J Hum Genet. 1992 Aug;51(2):344-56. Am J Hum Genet. 1992. PMID: 1642235 Free PMC article.
This paper presents the analysis of familial cancer data collected in a hospital-based study of 159 childhood soft-tissue-sarcoma patients. Two different statistical models detected excess aggregation of cancer, which could be explained by a rare domin …
This paper presents the analysis of familial cancer data collected in a hospital-based study of 159 childhood soft-tissue …
Pleomorphic rhabdomyosarcoma of the liver in an adult: a rare case report.
Okazaki M, Tajima H, Ohbatake Y, Shinbashi H, Nakanuma S, Makino I, Ninomiya I, Fushida S, Ohtsubo K, Ohta T. Okazaki M, et al. BMC Surg. 2020 Apr 21;20(1):81. doi: 10.1186/s12893-020-00742-7. BMC Surg. 2020. PMID: 32316960 Free PMC article.
BACKGROUND: Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of childhood soft tissue sarcoma. However, it infrequently occurs in adults and is uncommon in the liver. ...A percut …
BACKGROUND: Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of …
Joint effects of germ-line p53 mutation and sex on cancer risk in Li-Fraumeni syndrome.
Wu CC, Shete S, Amos CI, Strong LC. Wu CC, et al. Cancer Res. 2006 Aug 15;66(16):8287-92. doi: 10.1158/0008-5472.CAN-05-4247. Cancer Res. 2006. PMID: 16912210
For germ-line p53 mutation carriers, there is considerable variability with respect to age of cancer onset and tumor type, suggesting that additional genetic effects influence the clinical severity and tumor spectrum. To identify factors that might contribute to the observed …
For germ-line p53 mutation carriers, there is considerable variability with respect to age of cancer onset and tumor type, suggesting that a …
Individual-specific liability groups in genetic linkage, with applications to kindreds with Li-Fraumeni syndrome.
Shete S, Amos CI, Hwang SJ, Strong LC. Shete S, et al. Am J Hum Genet. 2002 Mar;70(3):813-7. doi: 10.1086/339370. Epub 2002 Jan 30. Am J Hum Genet. 2002. PMID: 11822026 Free PMC article.
Our simulation study shows that this approach yields higher LOD scores and more-accurate estimates of the recombination fraction in the families showing linkage. The proposed method is also applied to kindreds collected, at the M. D. Anderson Cancer Center, through proband …
Our simulation study shows that this approach yields higher LOD scores and more-accurate estimates of the recombination fraction in t …
Genetic analysis of childhood sarcoma.
Strong LC, Williams WR, Ferrell RE, Tainsky MA. Strong LC, et al. Princess Takamatsu Symp. 1989;20:151-7. Princess Takamatsu Symp. 1989. PMID: 2488230
A survey of cancer in 159 3-year survivors of childhood soft tissue sarcoma and their relatives revealed a cancer excess in first-degree relatives primarily due to cancers occurring before the age of 35 years and a highly significant excess in relative …
A survey of cancer in 159 3-year survivors of childhood soft tissue sarcoma and their relatives revealed a cance …
Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model.
Kaylani SZ, Xu J, Srivastava RK, Kopelovich L, Pressey JG, Athar M. Kaylani SZ, et al. Biochem Biophys Res Commun. 2013 Jun 14;435(4):557-61. doi: 10.1016/j.bbrc.2013.05.001. Epub 2013 May 9. Biochem Biophys Res Commun. 2013. PMID: 23665330
Rhabdomyosarcomas (RMS) represent the most common childhood soft-tissue sarcoma. Over the past few decades outcomes for low and intermediate risk RMS patients have slowly improved while patients with metastatic or relapsed RMS still face a grim prognos …
Rhabdomyosarcomas (RMS) represent the most common childhood soft-tissue sarcoma. Over the past few decades outco …
13 results