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Year Number of Results
1973 2
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1982 2
1983 3
1984 4
1985 7
1986 7
1987 9
1988 4
1989 7
1990 5
1991 3
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1994 13
1995 13
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1997 9
1998 13
1999 10
2000 10
2001 24
2002 11
2003 16
2004 11
2005 18
2006 24
2007 11
2008 12
2009 18
2010 17
2011 24
2012 19
2013 19
2014 25
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Quoted phrase not found in phrase index: "Childhood Central Nervous System Embryonal Tumor"
Page 1
Medulloblastoma.
Northcott PA, Robinson GW, Kratz CP, Mabbott DJ, Pomeroy SL, Clifford SC, Rutkowski S, Ellison DW, Malkin D, Taylor MD, Gajjar A, Pfister SM. Northcott PA, et al. Nat Rev Dis Primers. 2019 Feb 14;5(1):11. doi: 10.1038/s41572-019-0063-6. Nat Rev Dis Primers. 2019. PMID: 30765705 Review.
Medulloblastoma (MB) comprises a biologically heterogeneous group of embryonal tumours of the cerebellum. Four subgroups of MB have been described (WNT, sonic hedgehog (SHH), Group 3 and Group 4), each of which is associated with different genetic alterations, age at onset …
Medulloblastoma (MB) comprises a biologically heterogeneous group of embryonal tumours of the cerebellum. Four subgroups of MB have b …
Anti-GD2 Directed Immunotherapy for High-Risk and Metastatic Neuroblastoma.
Chan GC, Chan CM. Chan GC, et al. Biomolecules. 2022 Feb 24;12(3):358. doi: 10.3390/biom12030358. Biomolecules. 2022. PMID: 35327550 Free PMC article. Review.
Neuroblastoma is one of the few childhood cancers that carries a tumor-specific antigen in the form of a glycolipid antigen known as GD2. ...How to improve its efficacy is another challenge. Late relapse and central nervous system metastasis hav …
Neuroblastoma is one of the few childhood cancers that carries a tumor-specific antigen in the form of a glycolipid antigen kn …
Neuron-oligodendroglial interactions in health and malignant disease.
Taylor KR, Monje M. Taylor KR, et al. Nat Rev Neurosci. 2023 Dec;24(12):733-746. doi: 10.1038/s41583-023-00744-3. Epub 2023 Oct 19. Nat Rev Neurosci. 2023. PMID: 37857838 Free PMC article. Review.
Activity-dependent modulation of the myelinated infrastructure of the nervous system has emerged as a dimension of adaptive change during childhood development and in adulthood. Myelination is a richly dynamic process, with neuronal activity regulating oligod …
Activity-dependent modulation of the myelinated infrastructure of the nervous system has emerged as a dimension of adaptive ch …
National UK guidelines for the management of paediatric craniopharyngioma.
Gan HW, Morillon P, Albanese A, Aquilina K, Chandler C, Chang YC, Drimtzias E, Farndon S, Jacques TS, Korbonits M, Kuczynski A, Limond J, Robinson L, Simmons I, Thomas N, Thomas S, Thorp N, Vargha-Khadem F, Warren D, Zebian B, Mallucci C, Spoudeas HA. Gan HW, et al. Lancet Diabetes Endocrinol. 2023 Sep;11(9):694-706. doi: 10.1016/S2213-8587(23)00162-6. Epub 2023 Aug 4. Lancet Diabetes Endocrinol. 2023. PMID: 37549682 Review.
Although rare, craniopharyngiomas constitute up to 80% of tumours in the hypothalamic-pituitary region in childhood. Despite being benign, the close proximity of these tumours to the visual pathways, hypothalamus, and pituitary gland means that both treatment of the tumour …
Although rare, craniopharyngiomas constitute up to 80% of tumours in the hypothalamic-pituitary region in childhood. Despite being be …
Resolving medulloblastoma cellular architecture by single-cell genomics.
Hovestadt V, Smith KS, Bihannic L, Filbin MG, Shaw ML, Baumgartner A, DeWitt JC, Groves A, Mayr L, Weisman HR, Richman AR, Shore ME, Goumnerova L, Rosencrance C, Carter RA, Phoenix TN, Hadley JL, Tong Y, Houston J, Ashmun RA, DeCuypere M, Sharma T, Flasch D, Silkov A, Ligon KL, Pomeroy SL, Rivera MN, Rozenblatt-Rosen O, Rusert JM, Wechsler-Reya RJ, Li XN, Peyrl A, Gojo J, Kirchhofer D, Lötsch D, Czech T, Dorfer C, Haberler C, Geyeregger R, Halfmann A, Gawad C, Easton J, Pfister SM, Regev A, Gajjar A, Orr BA, Slavc I, Robinson GW, Bernstein BE, Suvà ML, Northcott PA. Hovestadt V, et al. Nature. 2019 Aug;572(7767):74-79. doi: 10.1038/s41586-019-1434-6. Epub 2019 Jul 24. Nature. 2019. PMID: 31341285 Free PMC article.
Medulloblastoma is a malignant childhood cerebellar tumour type that comprises distinct molecular subgroups. Whereas genomic characteristics of these subgroups are well defined, the extent to which cellular diversity underlies their divergent biology and clinical behaviour …
Medulloblastoma is a malignant childhood cerebellar tumour type that comprises distinct molecular subgroups. Whereas genomic characte …
Childhood cerebellar tumours mirror conserved fetal transcriptional programs.
Vladoiu MC, El-Hamamy I, Donovan LK, Farooq H, Holgado BL, Sundaravadanam Y, Ramaswamy V, Hendrikse LD, Kumar S, Mack SC, Lee JJY, Fong V, Juraschka K, Przelicki D, Michealraj A, Skowron P, Luu B, Suzuki H, Morrissy AS, Cavalli FMG, Garzia L, Daniels C, Wu X, Qazi MA, Singh SK, Chan JA, Marra MA, Malkin D, Dirks P, Heisler L, Pugh T, Ng K, Notta F, Thompson EM, Kleinman CL, Joyner AL, Jabado N, Stein L, Taylor MD. Vladoiu MC, et al. Nature. 2019 Aug;572(7767):67-73. doi: 10.1038/s41586-019-1158-7. Epub 2019 May 1. Nature. 2019. PMID: 31043743 Free PMC article.
Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that change over the course of development. Here we use single-cell transcriptomics to study more than 60,000 cells from the developing mouse …
Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that cha …
Pediatric low-grade glioma: State-of-the-art and ongoing challenges.
Fangusaro J, Jones DT, Packer RJ, Gutmann DH, Milde T, Witt O, Mueller S, Fisher MJ, Hansford JR, Tabori U, Hargrave D, Bandopadhayay P. Fangusaro J, et al. Neuro Oncol. 2024 Jan 5;26(1):25-37. doi: 10.1093/neuonc/noad195. Neuro Oncol. 2024. PMID: 37944912 Review.
The most common childhood central nervous system (CNS) tumor is pediatric low-grade glioma (pLGG), representing 30%-40% of all CNS tumors in children. Although there is high associated morbidity, tumor-related mortality is relatively rare …
The most common childhood central nervous system (CNS) tumor is pediatric low-grade glioma (pLGG), repres …
Childhood Medulloblastoma Revisited.
Cassia GSE, Alves CAPF, Taranath A, López NS, Oztekin O, Gonçalves FG, Patay Z. Cassia GSE, et al. Top Magn Reson Imaging. 2018 Dec;27(6):479-502. doi: 10.1097/RMR.0000000000000184. Top Magn Reson Imaging. 2018. PMID: 30516696 Review.
Medulloblastoma is the most common malignant solid tumor in childhood and the most common embryonal neuroepithelial tumor of the central nervous system. ...Accordingly, the 2016 revision of the World Health Organization's Classific …
Medulloblastoma is the most common malignant solid tumor in childhood and the most common embryonal neuroepithelial …
Mapping pediatric brain tumors to their origins in the developing cerebellum.
Okonechnikov K, Joshi P, Sepp M, Leiss K, Sarropoulos I, Murat F, Sill M, Beck P, Chan KC, Korshunov A, Sah F, Deng MY, Sturm D, DeSisto J, Donson AM, Foreman NK, Green AL, Robinson G, Orr BA, Gao Q, Darrow E, Hadley JL, Northcott PA, Gojo J, Kawauchi D, Hovestadt V, Filbin MG, von Deimling A, Zuckermann M, Pajtler KW, Kool M, Jones DTW, Jäger N, Kutscher LM, Kaessmann H, Pfister SM. Okonechnikov K, et al. Neuro Oncol. 2023 Oct 3;25(10):1895-1909. doi: 10.1093/neuonc/noad124. Neuro Oncol. 2023. PMID: 37534924 Free PMC article.
BACKGROUND: Distinguishing the cellular origins of childhood brain tumors is key for understanding tumor initiation and identifying lineage-restricted, tumor-specific therapeutic targets. ...CONCLUSION: Based on our results, individual cells within a tumor …
BACKGROUND: Distinguishing the cellular origins of childhood brain tumors is key for understanding tumor initiation and identi …
Unified rhombic lip origins of group 3 and group 4 medulloblastoma.
Smith KS, Bihannic L, Gudenas BL, Haldipur P, Tao R, Gao Q, Li Y, Aldinger KA, Iskusnykh IY, Chizhikov VV, Scoggins M, Zhang S, Edwards A, Deng M, Glass IA, Overman LM, Millman J, Sjoboen AH, Hadley J, Golser J, Mankad K, Sheppard H, Onar-Thomas A, Gajjar A, Robinson GW, Hovestadt V, Orr BA, Patay Z, Millen KJ, Northcott PA. Smith KS, et al. Nature. 2022 Sep;609(7929):1012-1020. doi: 10.1038/s41586-022-05208-9. Epub 2022 Sep 21. Nature. 2022. PMID: 36131015 Free PMC article.
Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into biologically distinct subgroups, suggesting that a personalized approach to therapy would be beneficial(1). ...Molecular signatures encoded within a human rhombic-lip-derived lineage traj …
Medulloblastoma, a malignant childhood cerebellar tumour, segregates molecularly into biologically distinct subgroups, suggesting tha …
576 results