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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
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1973 1
1975 2
1976 1
1977 3
1978 2
1979 1
1980 2
1982 3
1983 5
1984 5
1985 7
1986 4
1987 3
1988 5
1989 4
1990 10
1991 6
1992 6
1993 4
1994 5
1995 6
1996 9
1997 10
1998 11
1999 11
2000 11
2001 9
2002 9
2003 6
2004 4
2005 10
2006 10
2007 5
2008 8
2009 8
2010 12
2011 10
2012 5
2013 11
2014 7
2015 10
2016 16
2017 8
2018 8
2019 15
2020 9
2021 9
2022 9
2023 5
2024 7

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321 results

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Quoted phrase not found in phrase index: "Childhood Cerebral Anaplastic Astrocytoma"
Page 1
Childhood brain tumors: current management, biological insights, and future directions.
Pollack IF, Agnihotri S, Broniscer A. Pollack IF, et al. J Neurosurg Pediatr. 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. Epub 2019 Mar 1. J Neurosurg Pediatr. 2019. PMID: 30835699 Free PMC article. Review.
Brain tumors are the most common solid tumors in children, and, unfortunately, many subtypes continue to have a suboptimal long-term outcome. ...Herein, the authors review advances in the categorization and treatment of several of the more common pediatric brain tum …
Brain tumors are the most common solid tumors in children, and, unfortunately, many subtypes continue to have a suboptimal long-term …
Childhood cerebellar tumours mirror conserved fetal transcriptional programs.
Vladoiu MC, El-Hamamy I, Donovan LK, Farooq H, Holgado BL, Sundaravadanam Y, Ramaswamy V, Hendrikse LD, Kumar S, Mack SC, Lee JJY, Fong V, Juraschka K, Przelicki D, Michealraj A, Skowron P, Luu B, Suzuki H, Morrissy AS, Cavalli FMG, Garzia L, Daniels C, Wu X, Qazi MA, Singh SK, Chan JA, Marra MA, Malkin D, Dirks P, Heisler L, Pugh T, Ng K, Notta F, Thompson EM, Kleinman CL, Joyner AL, Jabado N, Stein L, Taylor MD. Vladoiu MC, et al. Nature. 2019 Aug;572(7767):67-73. doi: 10.1038/s41586-019-1158-7. Epub 2019 May 1. Nature. 2019. PMID: 31043743 Free PMC article.
Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that change over the course of development. Here we use single-cell transcriptomics to study more than 60,000 cells from the developing mouse …
Study of the origin and development of cerebellar tumours has been hampered by the complexity and heterogeneity of cerebellar cells that cha …
Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.
Fangusaro J, Onar-Thomas A, Young Poussaint T, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn LB, Goldman S, Pollack IF, Qaddoumi I, Jakacki RI, Fisher PG, Dhall G, Baxter P, Kreissman SG, Stewart CF, Jones DTW, Pfister SM, Vezina G, Stern JS, Panigrahy A, Patay Z, Tamrazi B, Jones JY, Haque SS, Enterline DS, Cha S, Fisher MJ, Doyle LA, Smith M, Dunkel IJ, Fouladi M. Fangusaro J, et al. Lancet Oncol. 2019 Jul;20(7):1011-1022. doi: 10.1016/S1470-2045(19)30277-3. Epub 2019 May 28. Lancet Oncol. 2019. PMID: 31151904 Free PMC article. Clinical Trial.
Selumetinib was provided as capsules given orally at the recommended phase 2 dose of 25 mg/m(2) twice daily in 28-day courses for up to 26 courses. The primary endpoint was the proportion of patients with a stratum-specific objective response (partial response or co …
Selumetinib was provided as capsules given orally at the recommended phase 2 dose of 25 mg/m(2) twice daily in 28-day courses for up …
Multiplatform molecular analyses refine classification of gliomas arising in patients with neurofibromatosis type 1.
Lucas CG, Sloan EA, Gupta R, Wu J, Pratt D, Vasudevan HN, Ravindranathan A, Barreto J, Williams EA, Shai A, Whipple NS, Bruggers CS, Maher O, Nabors B, Rodriguez M, Samuel D, Brown M, Carmichael J, Lu R, Mirchia K, Sullivan DV, Pekmezci M, Tihan T, Bollen AW, Perry A, Banerjee A, Mueller S, Gupta N, Hervey-Jumper SL, Oberheim Bush NA, Daras M, Taylor JW, Butowski NA, de Groot J, Clarke JL, Raleigh DR, Costello JF, Phillips JJ, Reddy AT, Chang SM, Berger MS, Solomon DA. Lucas CG, et al. Acta Neuropathol. 2022 Oct;144(4):747-765. doi: 10.1007/s00401-022-02478-5. Epub 2022 Aug 9. Acta Neuropathol. 2022. PMID: 35945463 Free PMC article.
Gliomas arising in the setting of neurofibromatosis type 1 (NF1) are heterogeneous, occurring from childhood through adulthood, can be histologically low-grade or high-grade, and follow an indolent or aggressive clinical course. ...The first harbored biallelic NF1 i …
Gliomas arising in the setting of neurofibromatosis type 1 (NF1) are heterogeneous, occurring from childhood through adulthood, can b …
Molecular genetics of gliomas.
Appin CL, Brat DJ. Appin CL, et al. Cancer J. 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. Cancer J. 2014. PMID: 24445767 Review.
Histologic classification is increasingly aided by molecular genetic studies, which assist in the diagnosis and provide prognostic and predictive value. Mutations in IDH1 are frequent in grades II and III astrocytomas, oligodendrogliomas, and oligoastrocytomas, as w …
Histologic classification is increasingly aided by molecular genetic studies, which assist in the diagnosis and provide prognostic an …
Posterior fossa tumors in children: current insights.
Formentin C, Joaquim AF, Ghizoni E. Formentin C, et al. Eur J Pediatr. 2023 Nov;182(11):4833-4850. doi: 10.1007/s00431-023-05189-5. Epub 2023 Sep 8. Eur J Pediatr. 2023. PMID: 37679511 Review.
Molecular biomarkers play an important role in the diagnosis, prognosis, and treatment of childhood posterior fossa tumors and can be used to predict patient outcomes and response to treatment and monitor its effectiveness. ...Conclusion: Molecular biomarkers …
Molecular biomarkers play an important role in the diagnosis, prognosis, and treatment of childhood posterior fossa tumors and …
Childhood cancer.
Miller RW, Young JL Jr, Novakovic B. Miller RW, et al. Cancer. 1995 Jan 1;75(1 Suppl):395-405. doi: 10.1002/1097-0142(19950101)75:1+<395::aid-cncr2820751321>3.0.co;2-w. Cancer. 1995. PMID: 8001010
Tumors were grouped histologically according to a classification previously utilized in an international volume of childhood cancer incidence. RESULTS: The most frequent histologic types were acute lymphocytic leukemia (23.6%), astrocytoma (9.6%), neuroblastoma (6.6 …
Tumors were grouped histologically according to a classification previously utilized in an international volume of childhood cancer i …
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034 Free PMC article.
In this study, we analyzed exome-wide human glioblastoma copy number data and found that cytoband 6q27 is an independent poor prognostic marker in multiple data sets. We then combined CRISPR-Cas9 data, human spatial transcriptomic data, and human and mouse RNA sequencing d …
In this study, we analyzed exome-wide human glioblastoma copy number data and found that cytoband 6q27 is an independent poor prognostic …
Epidemiology of childhood cancer.
Kaatsch P. Kaatsch P. Cancer Treat Rev. 2010 Jun;36(4):277-85. doi: 10.1016/j.ctrv.2010.02.003. Epub 2010 Mar 15. Cancer Treat Rev. 2010. PMID: 20231056 Review.
The present contribution reports childhood cancer incidence and survival rates as well as time trends and geographical variation. The report is based on the databases of population-based cancer registries which joined forces in cooperative projects such as Automated Chi …
The present contribution reports childhood cancer incidence and survival rates as well as time trends and geographical variation. The …
The proteomics of pediatric brain tumors.
Anagnostopoulos AK, Tsangaris GT. Anagnostopoulos AK, et al. Expert Rev Proteomics. 2014 Oct;11(5):641-8. doi: 10.1586/14789450.2014.939633. Epub 2014 Jul 25. Expert Rev Proteomics. 2014. PMID: 25059388 Review.
Input from these technologies gives scientists the advantage of early prognosis assessment, more accurate diagnosis and prospective curative intent in the pediatric brain tumor clinical setting. The present review aims to summarize current knowledge on research appl …
Input from these technologies gives scientists the advantage of early prognosis assessment, more accurate diagnosis and prospective c …
321 results