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Advances in the diagnosis and treatment of neuroblastoma.
Weinstein JL, Katzenstein HM, Cohn SL. Weinstein JL, et al. Oncologist. 2003;8(3):278-92. doi: 10.1634/theoncologist.8-3-278. Oncologist. 2003. PMID: 12773750 Free article. Review.
Neuroblastoma, a childhood neoplasm arising from neural crest cells, is characterized by a diversity of clinical behavior ranging from spontaneous remission to rapid tumor progression and death. To a large extent, outcome can be predicted by the stage of dise …
Neuroblastoma, a childhood neoplasm arising from neural crest cells, is characterized by a diversity of clinical behavior rang …
Family and parent-child relationship correlates of pediatric cancer survivors' substance use.
Tillery R, Willard VW, Gordon ML, Adams K, Long A, Phipps S. Tillery R, et al. J Cancer Surviv. 2022 Apr;16(2):329-337. doi: 10.1007/s11764-021-01026-6. Epub 2021 Mar 17. J Cancer Surviv. 2022. PMID: 33733380 Free PMC article.
Family functioning and caregiver relationship patterns did not predict AYA comparison substance use. CONCLUSION: AYA survivors were just as likely as AYA comparisons to engage in substance use, increasing their vulnerability to problematic health outcomes. ...
Family functioning and caregiver relationship patterns did not predict AYA comparison substance use. CONCLUSION: AYA survivors were j …
HOXB13 controls cell state through super-enhancers.
Aspuria PJ, Cheon DJ, Gozo MC, Beach JA, Recouvreux MS, Walts AE, Karlan BY, Orsulic S. Aspuria PJ, et al. Exp Cell Res. 2020 Aug 1;393(1):112039. doi: 10.1016/j.yexcr.2020.112039. Epub 2020 May 4. Exp Cell Res. 2020. PMID: 32376288 Free article.
Expression of the homeodomain transcription factor HOXB13 has been demonstrated in several malignancies but its role in tumorigenesis remains elusive. We observed high levels of HOXB13 in poorly differentiated pediatric tumors including a highly aggressive childhood
Expression of the homeodomain transcription factor HOXB13 has been demonstrated in several malignancies but its role in tumorigenesis remain …
Comprehensive Overview of Gene Rearrangements in Childhood T-Cell Acute Lymphoblastic Leukaemia.
Mroczek A, Zawitkowska J, Kowalczyk J, Lejman M. Mroczek A, et al. Int J Mol Sci. 2021 Jan 15;22(2):808. doi: 10.3390/ijms22020808. Int J Mol Sci. 2021. PMID: 33467425 Free PMC article. Review.
Acute lymphoblastic leukaemia (ALL) is a relevant form of childhood neoplasm, as it accounts for over 80% of all leukaemia cases. ...As molecular biology techniques provide insights into the biology of cancer, our study focuses on new potential therapeutic targets a …
Acute lymphoblastic leukaemia (ALL) is a relevant form of childhood neoplasm, as it accounts for over 80% of all leukaemia cas …
Lipoblastoma and liposarcoma in children: an analysis of 9 cases and a review of the literature.
Miller GG, Yanchar NL, Magee JF, Blair GK. Miller GG, et al. Can J Surg. 1998 Dec;41(6):455-8. Can J Surg. 1998. PMID: 9854536 Free PMC article. Review.
The myxoid liposarcoma karyotype was 46,XY,t(12;16)(q13;p11), and the lipoblastoma was reported as 46,XY,der(8)?t(8q;?),+mar. CONCLUSIONS: Lipoblastoma is an unusual childhood neoplasm and liposarcoma is very rare in children. Both tumours may present in a similar f …
The myxoid liposarcoma karyotype was 46,XY,t(12;16)(q13;p11), and the lipoblastoma was reported as 46,XY,der(8)?t(8q;?),+mar. CONCLUSIONS: L …
Programmed Death Ligand 1 Expression and Related Markers in Pleuropulmonary Blastoma.
Alipour Z, Schultz KAP, Chen L, Harris AK, Gonzalez IA, Pfeifer J, Hill DA, He M, Dehner LP. Alipour Z, et al. Pediatr Dev Pathol. 2021 Nov-Dec;24(6):523-530. doi: 10.1177/10935266211027417. Epub 2021 Jul 15. Pediatr Dev Pathol. 2021. PMID: 34266329 Free PMC article.
INTRODUCTION: Pleuropulmonary blastoma (PPB), a rare childhood neoplasm of the lung, is linked to pathogenic DICER1 variants. ...RESULTS: Twenty-five PPB cases were studied, consisting of Type I (n = 8, including 2 Ir), Type II (n = 8) and Type III (n = 9). PD-L1 co …
INTRODUCTION: Pleuropulmonary blastoma (PPB), a rare childhood neoplasm of the lung, is linked to pathogenic DICER1 variants. …
A dynamic mutational landscape associated with an inter-regionally diverse immune response in malignant rhabdoid tumour.
Yasui H, Valind A, Karlsson J, Pietras C, Jansson C, Wille J, Romerius P, Backman T, Gisselsson D. Yasui H, et al. J Pathol. 2020 Sep;252(1):22-28. doi: 10.1002/path.5490. Epub 2020 Jul 22. J Pathol. 2020. PMID: 32542645
Malignant rhabdoid tumour (MRT) is a childhood neoplasm of high malignancy characterised by biallelic mutation and/or loss of the epigenetic master regulator SMARCB1, accompanied by no or few other oncogenic drivers. ...Both patients showed a regionally heterogeneou …
Malignant rhabdoid tumour (MRT) is a childhood neoplasm of high malignancy characterised by biallelic mutation and/or loss of …
Advances in the diagnosis and treatment of neuroblastoma.
Katzenstein HM, Cohn SL. Katzenstein HM, et al. Curr Opin Oncol. 1998 Jan;10(1):43-51. doi: 10.1097/00001622-199801000-00008. Curr Opin Oncol. 1998. PMID: 9466484 Review.
Neuroblastoma, a childhood neoplasm arising from neural crest cells, is characterized by a diversity of clinical behavior, ranging from spontaneous remission to rapid tumor progression and death. To some extent, outcome can be predicted by the stage of diseas …
Neuroblastoma, a childhood neoplasm arising from neural crest cells, is characterized by a diversity of clinical behavior, ran …
Incidence of childhood cancer in Cuba (1986-1990).
Martín AA, Alert JA, Renó JS, Lonchong M, Grueiro S. Martín AA, et al. Int J Cancer. 1997 Aug 7;72(4):551-5. doi: 10.1002/(sici)1097-0215(19970807)72:4<551::aid-ijc1>3.0.co;2-p. Int J Cancer. 1997. PMID: 9259390 Free article.
Leukaemias, lymphomas and malignant tumours of the central nervous system were the most common childhood neoplasm groups. The majority of leukaemias were acute lymphoblastic leukaemias (ALL), and the incidence peak extended until 6 years of age. ...Most of the hepat …
Leukaemias, lymphomas and malignant tumours of the central nervous system were the most common childhood neoplasm groups. The …
A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma.
Calabrese FM, Clima R, Pignataro P, Lasorsa VA, Hogarty MD, Castellano A, Conte M, Tonini GP, Iolascon A, Gasparre G, Capasso M. Calabrese FM, et al. Oncotarget. 2016 Aug 2;7(31):49246-49258. doi: 10.18632/oncotarget.10271. Oncotarget. 2016. PMID: 27351283 Free PMC article.
BACKGROUND: Neuroblastoma, a tumor of the developing sympathetic nervous system, is a common childhood neoplasm that is often lethal. Mitochondrial DNA (mtDNA) mutations have been found in most tumors including neuroblastoma. ...The bioinformatics pipeline used to e …
BACKGROUND: Neuroblastoma, a tumor of the developing sympathetic nervous system, is a common childhood neoplasm that is often …
16 results