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Page 1
Pediatric atypical choroid plexus papilloma: Clinical features and diagnosis.
Chen Y, Zhao R, Shi W, Li H. Chen Y, et al. Clin Neurol Neurosurg. 2021 Jan;200:106345. doi: 10.1016/j.clineuro.2020.106345. Epub 2020 Nov 4. Clin Neurol Neurosurg. 2021. PMID: 33203591
OBJECTIVE: Atypical choroid plexus papilloma (aCPP) is a newly introduced subtype of choroid plexus tumors (CPTs) defined by the World Health Organization (WHO) in 2007 and is characterized by intermediate characteristics between choroid plexus papilloma (CPP) and choroid …
OBJECTIVE: Atypical choroid plexus papilloma (aCPP) is a newly introduced subtype of choroid plexus tumors (CPTs) defined by the World Healt …
Multi-omics analyses of choroid plexus carcinoma cell lines reveal potential targetable pathways and alterations.
Hesham D, On J, Alshahaby N, Amer N, Magdeldin S, Okada M, Tsukamoto Y, Hiraishi T, Imai C, Okuda S, Wakai T, Kakita A, Oishi M, El-Naggar S, Natsumeda M. Hesham D, et al. J Neurooncol. 2024 Jan;166(1):27-38. doi: 10.1007/s11060-023-04484-3. Epub 2024 Jan 8. J Neurooncol. 2024. PMID: 38190092
The discovered difference's importance and implications highlight the possible diversity of choroid plexus carcinoma and call for additional research to fully understand disease pathogenesis. CONCLUSION: Multi-omics analyses revealed that the two choroid …
The discovered difference's importance and implications highlight the possible diversity of choroid plexus carcinoma an …
Nervous system (NS) Tumors in Cancer Predisposition Syndromes.
Patil P, Pencheva BB, Patil VM, Fangusaro J. Patil P, et al. Neurotherapeutics. 2022 Oct;19(6):1752-1771. doi: 10.1007/s13311-022-01277-w. Epub 2022 Sep 2. Neurotherapeutics. 2022. PMID: 36056180 Free PMC article. Review.
Specifically, the cancer predisposition rate in pediatric patients with NS tumors has been reported to be as high as 15%, though it can approach 50% in certain tumor types (i.e., choroid plexus carcinoma associated with Li Fraumeni Syndrome). Cancer predispos …
Specifically, the cancer predisposition rate in pediatric patients with NS tumors has been reported to be as high as 15%, though it can appr …
Intraventricular choroid plexus tumors: clinical characteristics and impact of current management on survival.
Ruiz-Garcia H, Huayllani MT, Incontri D, Whaley JJ, Marenco-Hillembrand L, Ebot J, Chaichana KL, Sheehan J, Quiñones-Hinojosa A, Trifiletti DM. Ruiz-Garcia H, et al. J Neurooncol. 2020 Sep;149(2):283-292. doi: 10.1007/s11060-020-03603-8. Epub 2020 Sep 8. J Neurooncol. 2020. PMID: 32897467
On multivariable analysis, only patient age (p = 0.022), WHO grade (p = 0.003) and medical comorbidity scores (p = 0.002) were independently associated with OS after diagnosis. ...
On multivariable analysis, only patient age (p = 0.022), WHO grade (p = 0.003) and medical comorbidity scores (p = 0.002) were indepe …
Choroid plexus tumor epidemiology and outcomes: implications for surgical and radiotherapeutic management.
Cannon DM, Mohindra P, Gondi V, Kruser TJ, Kozak KR. Cannon DM, et al. J Neurooncol. 2015 Jan;121(1):151-7. doi: 10.1007/s11060-014-1616-x. Epub 2014 Oct 1. J Neurooncol. 2015. PMID: 25270349
Patient demographic data, histological classification (choroid plexus papilloma [CPP], atypical CPP [aCPP], and choroid plexus carcinoma [CPC]), extent of surgery, and use of radiation therapy (RT) as part of an initial course of therapy were analyzed for imp …
Patient demographic data, histological classification (choroid plexus papilloma [CPP], atypical CPP [aCPP], and choroid plexus …
Management of choroid plexus tumours: A comprehensive study from a tertiary hospital.
Konar SK, Kandregula S, Beniwal M, Sadashiva N, Patel KRK, Nagesh M, Rao KVLN, Vikas V, Raj P, Shashidhar A, Uppar AM, Shukla D, Indira Devi B, Srinivas D. Konar SK, et al. Clin Neurol Neurosurg. 2021 Feb;201:106454. doi: 10.1016/j.clineuro.2020.106454. Epub 2021 Jan 6. Clin Neurol Neurosurg. 2021. PMID: 33444945
Median Event-free survival was 65.83 months. A Cox regression analysis of predictors of overall survival of atypical CPP and CPC was done, in which age, sex, location, size, the extent of the resection, and complications were considered. ...
Median Event-free survival was 65.83 months. A Cox regression analysis of predictors of overall survival of atypical CPP and CPC was …
Choroid plexus tumors in adult and pediatric populations: the Cleveland Clinic and University Hospitals experience.
Bahar M, Hashem H, Tekautz T, Worley S, Tang A, de Blank P, Wolff J. Bahar M, et al. J Neurooncol. 2017 May;132(3):427-432. doi: 10.1007/s11060-017-2384-1. Epub 2017 Mar 13. J Neurooncol. 2017. PMID: 28290001
They are divided into choroid plexus papilloma (CPP), atypical choroid plexus papilloma (APP) and choroid plexus carcinoma (CPC). CPTs are known to primarily affect children less than 2 years of age. Gross total resection is the most important predictor …
They are divided into choroid plexus papilloma (CPP), atypical choroid plexus papilloma (APP) and choroid plexus carcinoma …
Molecular insights into malignant progression of atypical choroid plexus papilloma.
Yankelevich M, Finlay JL, Gorsi H, Kupsky W, Boue DR, Koschmann CJ, Kumar-Sinha C, Mody R. Yankelevich M, et al. Cold Spring Harb Mol Case Stud. 2021 Feb 19;7(1):a005272. doi: 10.1101/mcs.a005272. Print 2021 Feb. Cold Spring Harb Mol Case Stud. 2021. PMID: 33608379 Free PMC article.
We report a case of malignant transformation of choroid plexus papilloma to carcinoma in a 7-yr-old male with a germline TP53 mutation in which we present an analysis of molecular changes that might have led to the progression based on the next-generation genetic sequencing of bo …
We report a case of malignant transformation of choroid plexus papilloma to carcinoma in a 7-yr-old male with a germline TP53 mutation in wh …
An update on the CNS manifestations of brain tumor polyposis syndromes.
Kim B, Tabori U, Hawkins C. Kim B, et al. Acta Neuropathol. 2020 Apr;139(4):703-715. doi: 10.1007/s00401-020-02124-y. Epub 2020 Jan 22. Acta Neuropathol. 2020. PMID: 31970492 Review.
Tumor specificity does exist as medulloblastoma occur in FAP, LFS and CMMRD while glioma are most commonly seen in all replication repair-deficient genes and LFS. Choroid plexus carcinoma is strictly observed in LFS while Cowden syndrome patients devel …
Tumor specificity does exist as medulloblastoma occur in FAP, LFS and CMMRD while glioma are most commonly seen in all replication repair-de …
Erythropoietin receptor expression in normal and neoplastic choroid plexus.
Beschorner R, Psaras T, Meyermann R, Bremer J, Schmidt T, Mittelbronn M, Schittenhelm J. Beschorner R, et al. Clin Neuropathol. 2011 Jan-Feb;30(1):33-40. doi: 10.5414/npp30033. Clin Neuropathol. 2011. PMID: 21176716
CPT samples consisted of choroid plexus papillomas/CPP (n = 41), atypical CPP (n = 15) and choroid plexus carcinoma/CPC (n = 1). EpoR expression was determined by immunohistochemistry using semi-quantitative scoring for staining intensity and was validated in …
CPT samples consisted of choroid plexus papillomas/CPP (n = 41), atypical CPP (n = 15) and choroid plexus carcinoma/CPC …
58 results