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Quoted phrase not found in phrase index: "Chronic Eosinophilic Leukemia with FIP1L1-PDGFRA"
Page 1
Hypereosinophilic Syndrome.
Curtis C, Ogbogu P. Curtis C, et al. Clin Rev Allergy Immunol. 2016 Apr;50(2):240-51. doi: 10.1007/s12016-015-8506-7. Clin Rev Allergy Immunol. 2016. PMID: 26475367 Review.
This entity has been recognized for decades, with early studies identifying distinct groups of patients with differing symptoms, exam findings, laboratory abnormalities, and prognosis. In the past, these patients were treated with non-targeted immunosuppressive agents, oft …
This entity has been recognized for decades, with early studies identifying distinct groups of patients with differing symptoms, exam findin …
World Health Organization-defined eosinophilic disorders: 2019 update on diagnosis, risk stratification, and management.
Shomali W, Gotlib J. Shomali W, et al. Am J Hematol. 2019 Oct;94(10):1149-1167. doi: 10.1002/ajh.25617. Am J Hematol. 2019. PMID: 31423623 Free article. Review.
They include morphologic review of the blood and marrow, standard cytogenetics, fluorescence in situ-hybridization, flow immunophenotyping, and T-cell clonality assessment to detect histopathologic or clonal evidence for an acute or chronic hematolymphoid neoplasm. RISK STRATIFIC …
They include morphologic review of the blood and marrow, standard cytogenetics, fluorescence in situ-hybridization, flow immunophenotyping, …
Mast cells and eosinophils in mastocytosis, chronic eosinophilic leukemia, and non-clonal disorders.
Gotlib J, Akin C. Gotlib J, et al. Semin Hematol. 2012 Apr;49(2):128-37. doi: 10.1053/j.seminhematol.2012.01.007. Semin Hematol. 2012. PMID: 22449623 Review.
The dysregulated tyrosine kinases, D816V KIT and FIP1L1-PDGFRA, are the prototypic oncogenic lesions resulting in systemic mastocytosis (SM) and chronic eosinophilic leukemia, respectively. We review the pathobiology of these myeloproliferative neoplasms (MPN …
The dysregulated tyrosine kinases, D816V KIT and FIP1L1-PDGFRA, are the prototypic oncogenic lesions resulting in systemic mastocytosis (SM) …
The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management.
Gotlib J, Cools J, Malone JM 3rd, Schrier SL, Gilliland DG, Coutré SE. Gotlib J, et al. Blood. 2004 Apr 15;103(8):2879-91. doi: 10.1182/blood-2003-06-1824. Epub 2003 Nov 20. Blood. 2004. PMID: 15070659 Free article. Review.
Idiopathic hypereosinophilic syndrome (HES) and chronic eosinophilic leukemia (CEL) comprise a spectrum of indolent to aggressive diseases characterized by unexplained, persistent hypereosinophilia. ...
Idiopathic hypereosinophilic syndrome (HES) and chronic eosinophilic leukemia (CEL) comprise a spectrum of indolent to …
Venous thrombosis and predictors of relapse in eosinophil-related diseases.
Réau V, Vallée A, Terrier B, Plessier A, Abisror N, Ackermann F, Benainous R, Bohelay G, Chabi-Charvillat ML, Cornec D, Desbois AC, Faguer S, Freymond N, Gaillet A, Hamidou M, Killian M, Le Jeune S, Marchetti A, Meyer G, Osorio-Perez F, Panel K, Rautou PE, Rohmer J, Simon N, Tcherakian C, Vasse M, Zuelgaray E, Lefevre G, Kahn JE, Groh M. Réau V, et al. Sci Rep. 2021 Mar 18;11(1):6388. doi: 10.1038/s41598-021-85852-9. Sci Rep. 2021. PMID: 33737704 Free PMC article.
We aimed to report on the clinical features and treatment outcomes of patients with unexplained VT and eosinophilia, and to identify predictors of relapse. This retrospective, multicenter, observational study included patients aged over 15 years with VT, concomitant blood …
We aimed to report on the clinical features and treatment outcomes of patients with unexplained VT and eosinophilia, and to identify pred …
Generalized Eruptive Histiocytosis Associated With FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia.
Ziegler B, Peitsch WK, Reiter A, Marx A, Goerdt S, Géraud C. Ziegler B, et al. JAMA Dermatol. 2015 Jul;151(7):766-9. doi: 10.1001/jamadermatol.2015.0154. JAMA Dermatol. 2015. PMID: 25923837
Morphologic and molecular analyses from bone marrow and blood samples revealed FIP1L1-PDGFRA-positive chronic eosinophilic leukemia. The patient was treated with imatinib and achieved complete clinical remission of his leukemia and the GEH. CONCLUSIONS AND RE …
Morphologic and molecular analyses from bone marrow and blood samples revealed FIP1L1-PDGFRA-positive chronic eosinophilic …
Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias.
Vandenberghe P, Wlodarska I, Michaux L, Zachée P, Boogaerts M, Vanstraelen D, Herregods MC, Van Hoof A, Selleslag D, Roufosse F, Maerevoet M, Verhoef G, Cools J, Gilliland DG, Hagemeijer A, Marynen P. Vandenberghe P, et al. Leukemia. 2004 Apr;18(4):734-42. doi: 10.1038/sj.leu.2403313. Leukemia. 2004. PMID: 14973504
Detection of the FIP1L1-PDGFRA fusion gene or the corresponding cryptic 4q12 deletion supports the diagnosis of chronic eosinophilic leukemia (CEL) in patients with chronic hypereosinophilia. ...
Detection of the FIP1L1-PDGFRA fusion gene or the corresponding cryptic 4q12 deletion supports the diagnosis of chronic eosinophil …
A case of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia with a rare FIP1L1 breakpoint.
Lambert F, Heimann P, Herens C, Chariot A, Bours V. Lambert F, et al. J Mol Diagn. 2007 Jul;9(3):414-9. doi: 10.2353/jmoldx.2007.060196. J Mol Diagn. 2007. PMID: 17591942 Free PMC article.
The idiopathic hypereosinophilic syndrome (HES) has remained for a long time a diagnosis of exclusion. Differential diagnosis between the HES and the related chronic eosinophilic leukemia (CEL) relied on the identification of signs of clonality that allowed, …
The idiopathic hypereosinophilic syndrome (HES) has remained for a long time a diagnosis of exclusion. Differential diagnosis between the HE …
KIT D816V-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia are distinct entities.
Maric I, Robyn J, Metcalfe DD, Fay MP, Carter M, Wilson T, Fu W, Stoddard J, Scott L, Hartsell M, Kirshenbaum A, Akin C, Nutman TB, Noel P, Klion AD. Maric I, et al. J Allergy Clin Immunol. 2007 Sep;120(3):680-7. doi: 10.1016/j.jaci.2007.05.024. Epub 2007 Jul 12. J Allergy Clin Immunol. 2007. PMID: 17628645
BACKGROUND: The broad and overlapping clinical manifestations of D816V KIT-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia (CEL), coupled with the increase in activated eosinophils an …
BACKGROUND: The broad and overlapping clinical manifestations of D816V KIT-associated systemic mastocytosis with eosinophilia and FIP1L1/ …
The diagnosis of BCR/ABL-negative chronic myeloproliferative diseases (CMPD): a comprehensive approach based on morphology, cytogenetics, and molecular markers.
Haferlach T, Bacher U, Kern W, Schnittger S, Haferlach C. Haferlach T, et al. Ann Hematol. 2008 Jan;87(1):1-10. doi: 10.1007/s00277-007-0403-6. Epub 2007 Oct 16. Ann Hematol. 2008. PMID: 17938925 Free PMC article. Review.
Recent years showed significant progress in the molecular characterization of the chronic myeloproliferative disorders (CMPD) which are classified according to the WHO classification of 2001 as polycythemia vera (PV), chronic idiopathic myelofibrosis (CIMF), essential thrombocyth …
Recent years showed significant progress in the molecular characterization of the chronic myeloproliferative disorders (CMPD) which are clas …
18 results