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Quoted phrase not found in phrase index: "Chronic Lymphocytic Leukemia with Immunoglobulin Heavy Chain Variable-Region Gene Somatic Hypermutation"
Page 1
Genetics and epigenetics of CLL.
Paul P, Stüssi G, Bruscaggin A, Rossi D. Paul P, et al. Leuk Lymphoma. 2023 Mar;64(3):551-563. doi: 10.1080/10428194.2022.2153359. Epub 2022 Dec 12. Leuk Lymphoma. 2023. PMID: 36503384 Review.
Chronic lymphocytic leukemia (CLL) has a heterogeneous biological behavior, which is highly influenced by its immunogenetic, epigenetic, and genomic properties. The remarkably variable clinical course of the disease has been associated with genetic fea …
Chronic lymphocytic leukemia (CLL) has a heterogeneous biological behavior, which is highly influenced by its immunogen …
Molecular pathogenesis of chronic lymphocytic leukemia.
Gaidano G, Foà R, Dalla-Favera R. Gaidano G, et al. J Clin Invest. 2012 Oct;122(10):3432-8. doi: 10.1172/JCI64101. Epub 2012 Oct 1. J Clin Invest. 2012. PMID: 23023714 Free PMC article. Review.
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. ...Many CLL patients carry mutated immuno-globulin heavy-chain variable genes, while approximately 35% harbor unmutated IgV genes, which are associate …
Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. ...Many CLL patients carry mutated imm …
Inherited predisposition to chronic lymphocytic leukemia.
Brown JR. Brown JR. Expert Rev Hematol. 2008 Oct;1(1):51-61. doi: 10.1586/17474086.1.1.51. Expert Rev Hematol. 2008. PMID: 19802369 Free PMC article. Review.
Inherited susceptibility to chronic lymphocytic leukemia (CLL) has been recognized for decades. ...Studies of familial CLL have suggested that the disease features are largely similar to sporadic CLL, although recent data suggest that familial CLL may more co …
Inherited susceptibility to chronic lymphocytic leukemia (CLL) has been recognized for decades. ...Studies of familial …
What do somatic hypermutation and class switch recombination teach us about chronic lymphocytic leukaemia pathogenesis?
Oppezzo P, Dighiero G. Oppezzo P, et al. Curr Top Microbiol Immunol. 2005;294:71-89. doi: 10.1007/3-540-29933-5_5. Curr Top Microbiol Immunol. 2005. PMID: 16323428 Review.
Interestingly, the presence or absence of somatic hypermutation (SHM) process is associated with the use of particular VH genes. ...In CLL with mutated Ig genes, the proliferating B cell may have transited through germinal centres, the ph …
Interestingly, the presence or absence of somatic hypermutation (SHM) process is associated with the use of particular VH g …
Pathology consultation on evaluating prognosis in incidental monoclonal lymphocytosis and chronic lymphocytic leukemia.
Siddon AJ, Rinder HM; Education Committee of the Academy of Clinical Laboratory Physicians and Scientists. Siddon AJ, et al. Am J Clin Pathol. 2013 Jun;139(6):708-12. doi: 10.1309/AJCPLIR4GZWX3XKA. Am J Clin Pathol. 2013. PMID: 23690112 Review.
Chronic lymphocytic leukemia (CLL) is a monoclonal B-cell lymphoproliferative disorder generally characterized by an indolent clinical course. ...Laboratory studies include surface CD38 and intracellular ZAP-70 expression by flow cytometr …
Chronic lymphocytic leukemia (CLL) is a monoclonal B-cell lymphoproliferative disorder generally characte …
Immunoglobulin gene rearrangements and mutational status in argentinian patients with chronic lymphocytic leukemia.
Stanganelli C, Travella A, Bezares R, Slavutsky I. Stanganelli C, et al. Clin Lymphoma Myeloma Leuk. 2013 Aug;13(4):447-457.e2. doi: 10.1016/j.clml.2013.02.019. Epub 2013 May 9. Clin Lymphoma Myeloma Leuk. 2013. PMID: 23665144
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease. The mutational status of the immunoglobulin heavy chain variable (IGHV) region represents one of the best prognostic markers and defines 2 diseas …
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease. The mutational status of the i …
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes.
Xochelli A, Baliakas P, Kavakiotis I, Agathangelidis A, Sutton LA, Minga E, Ntoufa S, Tausch E, Yan XJ, Shanafelt T, Plevova K, Boudjogra M, Rossi D, Davis Z, Navarro A, Sandberg Y, Vojdeman FJ, Scarfo L, Stavroyianni N, Sudarikov A, Veronese S, Tzenou T, Karan-Djurasevic T, Catherwood M, Kienle D, Chatzouli M, Facco M, Bahlo J, Pott C, Pedersen LB, Mansouri L, Smedby KE, Chu CC, Giudicelli V, Lefranc MP, Panagiotidis P, Juliusson G, Anagnostopoulos A, Vlahavas I, Antic D, Trentin L, Montillo M, Niemann C, Döhner H, Langerak AW, Pospisilova S, Hallek M, Campo E, Chiorazzi N, Maglaveras N, Oscier D, Gaidano G, Jelinek DF, Stilgenbauer S, Chouvarda I, Darzentas N, Belessi C, Davi F, Hadzidimitriou A, Rosenquist R, Ghia P, Stamatopoulos K. Xochelli A, et al. Clin Cancer Res. 2017 Sep 1;23(17):5292-5301. doi: 10.1158/1078-0432.CCR-16-3100. Epub 2017 May 23. Clin Cancer Res. 2017. PMID: 28536306
Purpose: We sought to investigate whether B cell receptor immunoglobulin (BcR IG) stereotypy is associated with particular clinicobiological features among chronic lymphocytic leukemia (CLL) patients expressing mutated BcR IG (M-CLL) enco …
Purpose: We sought to investigate whether B cell receptor immunoglobulin (BcR IG) stereotypy is associated with particu …
Immunoglobulin heavy chain variable region gene usage and mutational status of the leukemic B cells in Iranian patients with chronic lymphocytic leukemia.
Hojjat-Farsangi M, Jeddi-Tehrani M, Razavi SM, Sharifian RA, Mellstedt H, Shokri F, Rabbani H. Hojjat-Farsangi M, et al. Cancer Sci. 2009 Dec;100(12):2346-53. doi: 10.1111/j.1349-7006.2009.01341.x. Epub 2009 Sep 2. Cancer Sci. 2009. PMID: 19824994 Free article.
The mutational status of the immunoglobulin variable region heavy chain genes (IGHV) is an important prognostic marker in chronic lymphocytic leukemia (CLL). ...Little is known about Asian CLL patients. In this …
The mutational status of the immunoglobulin variable region heavy chain genes (IGHV) is an importa …
The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia.
Dyer MJ, Oscier DG. Dyer MJ, et al. Leukemia. 2002 Jun;16(6):973-84. doi: 10.1038/sj.leu.2402528. Leukemia. 2002. PMID: 12040429 Review.
B cell chronic lymphocytic leukemia (CLL) lacks a consistent genetic abnormality. ...Immunoglobulin gene chromosomal translocations are rare in CLL and involve a distinct subset of genes including BCL3, BCL11A and CCND2. ...
B cell chronic lymphocytic leukemia (CLL) lacks a consistent genetic abnormality. ...Immunoglobulin …
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in chronic lymphocytic leukemia.
Blachly JS, Ruppert AS, Zhao W, Long S, Flynn J, Flinn I, Jones J, Maddocks K, Andritsos L, Ghia EM, Rassenti LZ, Kipps TJ, de la Chapelle A, Byrd JC. Blachly JS, et al. Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4322-7. doi: 10.1073/pnas.1503587112. Epub 2015 Mar 18. Proc Natl Acad Sci U S A. 2015. PMID: 25787252 Free PMC article.
Immunoglobulins (Ig) are produced by B lymphocytes as secreted antibodies or as part of the B-cell receptor. There is tremendous diversity of potential Ig transcripts (>1 10(12)) as a result of hundreds of germ-line gene segments, random nucleotide incorpo …
Immunoglobulins (Ig) are produced by B lymphocytes as secreted antibodies or as part of the B-cell receptor. There is tremendo …
48 results